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Yohimbine

Yohimbine Dosage & Review

Yohimbine Review Yohimbine is a substance that is extracted from the bark of the yohimbe tree which is commonly found in Africa. It is often regarded as a stimulant drug that could give aphrodisiac effects and is used often to treat erectile dysfunction. In addition to its stimulating effects, it also functions as an energy-boosting drug thus, leading to alertness, awareness and increased motivation. It also has a positive inpact on memory and concentration owing to the stimulation of the central nervous system. Moreover, it has been used as a fat burning supplement and is used by athletes due to the increased adrenaline levels provided. Yohimbine is categorized under Psychostimulants. It is also known as Yohimbe, Corynanthe Yohimbe, Yohimbe Bark, Pausinystalia Yohimbe.
Yohimbine
Also Known Yohimbe, Corynanthe Yohimbe, Yohimbe Bark, Pausinystalia Yohimbe
Description Yohimbine is a substance that is extracted from the bark of the yohimbe tree which is commonly found in Africa. It is often regarded as a stimulant drug that could give aphrodisiac effects and is used often to treat erectile dysfunction. In addition to its stimulating effects, it also functions as an energy-boosting drug thus, leading to alertness, awareness and increased motivation. It also has a positive inpact on memory and concentration owing to the stimulation of the central nervous system. Moreover, it has been used as a fat burning supplement and is used by athletes due to the increased adrenaline levels provided.
Typical Dose 0.2mg/kg
Stacks
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Benefits and Effectiveness

  • Anxiety - Increased [1]
  • Blood Pressure - Increased [2]
  • Cortisol - Increased [3]
  • Erections - Increased [4]
  • Fat Mass - Decrease [5]
  • Heart Rate - Increased [6]
  • Lean Mass - Neutral [7]
  • Power Output - Neutral [8]

Yohimbine Dosage

0.2mg/kg

Side Effects

Associated side effects with Yohimbine usage include headaches, gastointestinal and sleep disturbances, hypertension, irritability, nausea and vomiting. When used in high doses, it may result in difficulty breathing, paralysis, low blood pressure, heart problems, and even death.

Yohimbine Review: What is Yohimbine?

Yohimbine is an active chemical found in the bark of the West African evergreen tree that grows in Nigeria, Gabon, Congo and Cameroon. In Africa, it has been traditionally used for the treatment of coughs, fever, leprosy, and as a natural aphrodisiac. At the present time, it is classified as a prescription medicine in the United States as a treatment for erectile dysfunction and can even be used to replace Viagra.

What are the benefits of Yohimbine and its mechanism of action?

Aside from the things mentioned earlier, what more can Yohimbine offer to us? Yohimbine is a mild MAOI inhibitor with stimulant and aphrodisiac effects. It acts as a pre-synaptic alpha-2 adrenergic receptor blocking agent or antagonist. With this, it increases the activity of our body’s Central Nervous System particularly that of the Sympathetic Nervous System. As a stimulant, it increases the release of both epinephrine and norepinephrine. Epinephrine, also known as adrenaline, is the neurotransmitter involved in our body’s “fight or flight"response. It provides our muscles the energy to respond quickly and more effectively when faced in a threat (4). Meanwhile, norepinephrine is the neurotransmitter also being referred to as the stress hormone. As the name implies, it is responsible for our body’s ability to respond to stress and is also involved in the “fight or flight"response. Norepinephrine increases a person’s breathing rate and heart rate thus, increasing blood circulation. And with an increase in blood flow, there will be more glucose and oxygen delivered to our working muscles as well as to our neurons in the brain (5). With Yohimbine’s influence on the two neurotransmitters, there will be a boost in brain power and physical energy as well as an increase in metabolism and faster neuronal communication. There would be an increase in an individual’s alertness, motivation, focus, stamina, cognitive speed, and a general mental performance.

Yohimbine is widely known to be a libido enhancer and a treatment for erectile dysfunction. But how does this supplement do such effect? Basically when taken in higher dosages, Yohimbine produces an increase in blood pressure and heart rate. However when consumed in lower dosages, its effects are already opposite such as a decrease in blood pressure through vasodilation. Now with vasodilation, there is a reduction in the vascular resistance and an easier flow of blood within the blood vessels. With this, sexual benefits are experienced through an increase in circulation to the sexual organs. In relation to an increased blood flow, researches are now studying Yohimbine as a potential treatment for Type II Diabetes. This is then attributed to an improved circulation to the hands and feet as well.

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On the other hand, Yohimbine also poses to have benefits as a fat burning and muscle building compound. It has even been used in fat loss aids and dietary supplements. Yohimbine reviews state that the supplement is a good addition to their pre-workout routine since it enhances one’s performance. But how does Yohimbine do this? Basically, this is due to an increased level of both ephinephrine and norepinephrine and an increase in thermogenesis. Also, Yohimbine increases metabolism by targeting the storage of lipids and deposits and also blocks receptors that inhibit fat loss. Through these mechanisms, there would be an increase in the fat burning process.

Yohimbine also promotes a healthy body. It works as an antioxidant that targets toxins and free radicals that may damage our bodies. And as we all know, free radicals refer to molecules that are unstable and highly reactive causing damage to cells. Because of this damage, it may lead to a number of diseases such as cancer, cardiovascular diseases, and age-related diseases (1). Antioxidants, like Yohimbine, work by neutralizing these free radicals and oxidative stress thus, preventing the destructive processes that the latter may bring. Being an antioxidant, Yohimbine will significantly boost our immune system in defending itself from diseases and infection. Because of this property that Yohimbine possesses, it will promote a healthier body and brain, protecting and preventing us from accumulating diseases in the future.

What should I consider before taking Yohimbine?

Taking any supplement at the right amount is very crucial for its effectiveness. With regards to Yohimbine dosage, how much of it do we really need each day? Basically, there has not been any approved recommended dosage yet for this supplement. But, your daily intake greatly depends on the reason as to why you are taking this supplement. For weight loss purposes, a daily dose of 20 mg is already sufficient. When aiming to treat erectile dysfunction, a lesser dose of 5 mg to 10 mg is needed.

When starting with any new drug or supplement, it would be best to start off with the lowest possible dose to see how you respond and then gradually increasing it over time. You might also want to consider consulting your doctor or healthcare provider first since a person’s condition and health status may play a role.

The use of Yohimbine has been linked to a variety of side effects. This includes but are limited to, stomach upset, tremor, excitation, sleep disturbances, tachycardia, dizziness, high blood pressure, anxiety or agitation, headache, bloating, rash, nausea, vomiting, and frequent urination. When taken in excessive dosages, it may cause additional problems such as very low blood pressure, paralysis, difficulty breathing, heart issues and even death

It is important to note that some people may be contraindicated to Yohimbine use. This includes children, pregnant and lactating women, individuals suffering from PTSD, liver disease, kidney disease, high or low blood pressure, depression, chest pain, heart disease, or diabetes. Also, people suffering from schizophrenia and prostate problems should use this with caution.

In addition to that, Yohimbine may interact with other medications and should not be used in accordance with them. This includes but is not limited to medications for depression such as the MAOIs and antidepressants, Clonidine, Guanabenz, medications changed by the liver such as CYP2D6 substrates, antihypertensive drugs, anticoagulant or antiplatelet drugs, Naloxone, Phenothiazines, and stimulant drugs. (6)

Where can I buy Yohimbine?

You can purchase Yohimbine online and in numerous health stores. Drug is available over the counter and thus, does not require prescription from a doctor. Buy Yohimbine now and experience it's benefits. The link above is to the brand we recommend.

Yohimbine Closing Thoughts

Although this supplement is a very promising one and has its numerous health and cognitive benefits, one should be sure of taking this due to its related adverse effects. Also, you should consult your doctor or health care provider before taking this supplement and should follow their instructions at all time. If you wanted to have a significant step up in your cognitive function while having fewer side effects, you might want to consider other potent nootropics such as Noopept, Piracetam, Adrafinil, Alpha GPC, and among many others. However if you are looking for a more natural stack, Ginkgo Biloba, Lion’s Mane Mushroom, and many others are also at hand.

References:
  1. http://www.thefreedictionary.com/free+radical
  2. https://umm.edu/health/medical/drug-notes/notes/yohimbine-by-mouth
  3. https://umm.edu/health/medical/altmed/condition/sexual-dysfunction
  4. http://www.news-medical.net/health/What-is-Epinephrine-%28Adrenaline%29.aspx
  5. http://study.com/academy/lesson/what-is-norepinephrine-effects-function-definition.html
  6. https://www.nlm.nih.gov/medlineplus/druginfo/natural/759.html
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^1 http://www.ncbi.nlm.nih.gov/pubmed/21710402
^1 http://www.ncbi.nlm.nih.gov/pubmed/21289601
^2 http://www.ncbi.nlm.nih.gov/pubmed/21710402
^2 http://www.ncbi.nlm.nih.gov/pubmed/10949101
^3 http://www.ncbi.nlm.nih.gov/pubmed/21710402
^3 http://www.ncbi.nlm.nih.gov/pubmed/21289601
^4 http://www.ncbi.nlm.nih.gov/pubmed/9649257
^5 http://www.ncbi.nlm.nih.gov/pubmed/17214405
^6 http://www.ncbi.nlm.nih.gov/pubmed/21710402
^6 http://www.ncbi.nlm.nih.gov/pubmed/10949101
^7 http://www.ncbi.nlm.nih.gov/pubmed/17214405
^8 http://www.ncbi.nlm.nih.gov/pubmed/17214405

No article available.

Comparisons [ top]

Versus ComparisonCaffeine vs YohimbineNicotine vs YohimbineMarijuana vs Yohimbine
Anxiety | | |
Blood Pressure | | |
Cortisol | | |
Heart Rate | | |

Results & Experiences

Daily Dosage # Stacks
12.00 mg 1
25.00 mg 1
18.00 mg 1
5.00 mg 1
2.68 mg 1
Purpose # Stacks Effectiveness
Lipodystrophy (lipoatrophy or loss of fatty tissue) 1
Unknown
Can't tell
None
Slight
Moderate
Major

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Wiki Last Updated: 2016-04-01