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Phenylalanine

Phenylalanine Dosage & Review

Phenylalanine Review Phenylalanine is an essential amino acid that is converted into Phenylethylamine, and ultimately increases levels of dopamine, norepinephrine, and epinephrine within the brain. When supplemented at significant levels, it may actually disrupt serotonin production. Due to the increase in neurotransmitters that are commonly involved in concentration, critical thinking, and memory, it is thought to have a minor nootropic effect. Moreover, it is currently being used as a treatment for depression, bipolar disorder, and Parkinson's disease. Phenylalanine is categorized under Nutrients. It is also known as L-Phenylalanine, DL-Phenylalanine, DLPA, D-phenylalanine.
Phenylalanine
Also Known L-Phenylalanine, DL-Phenylalanine, DLPA, D-phenylalanine
Description Phenylalanine is an essential amino acid that is converted into Phenylethylamine, and ultimately increases levels of dopamine, norepinephrine, and epinephrine within the brain. When supplemented at significant levels, it may actually disrupt serotonin production. Due to the increase in neurotransmitters that are commonly involved in concentration, critical thinking, and memory, it is thought to have a minor nootropic effect. Moreover, it is currently being used as a treatment for depression, bipolar disorder, and Parkinson's disease.
Typical Dose 50-100 mg/kg
Stacks
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Benefits and Effectiveness

Phenylalanine Dosage

50-100 mg/kg

Side Effects

Some reported side effects include headaches, nausea and heart burn.

Phenylalanine Review: What is Phenylalanine?

Being anxious and stressed puts you into a bad mood. This then affects your quality of sleep and your overall cognitive and physical performance leading you to low productivity levels. So how can you possibly combat this problem in just one supplement? Phenylalanine is the answer. Basically, Phenylalanine is an essential amino acid needed for our bodily functions but our body cannot produce it. That is why supplementation of Phenylalanine is important. It generally comes in 3 forms: L-phenylalanine which is found in protein-rich foods such as beef, eggs, cheese, milk and other products, D-phenylalanine which is a synthetic version of the former, and DL-phenylalanine which is the combination of the two forms. Having a better understanding of the supplements around such as Phenylalanine will lead us to maximizing our brain’s potential. Let us now understand what Phenylalanine does and why supplementation of this drug is vital.

What are the effects of Phenylalanine and its mechanism of action?

What makes Phenylalanine one of the best nootropics around is that it has the ability to cross the blood-brain barrier effectively. Because of this, it is highly potent and can produce its benefits quickly. Let us now know what Phenylalanine has to offer and how it works in our body to deliver its effects.

1. Phenylalanine for mood

Since Phenylalanine is a precursor to Tyrosine, it influences the production of various proteins, hormones and neurotransmitters. And an important neurotransmitter positively being affected is Dopamine. Dopamine is responsible for an individual’s memory and learning capabilities, attention, pleasurable reward, behaviour and cognition, and most especially for mood and sleep (3). With an increased level of this neurotransmitter, there will be a significant improvement in one’s mood and sleeping patterns. This will then translate into a general feeling of wellness and a positive attitude in doing both mental and physical activities. Because of this mechanism, it will also be of great benefit for those people experiencing stress, depression and anxiety.

2. Phenylalanine for energy

Now, how does Phenylalanine contribute to an increase in mental and physical energy? This is still through the influence of Phenylalanine in the production of neurotransmitters. Along with Dopamine, Epinephrine and Norepinephrine levels are also raised. Epinephrine, also known as adrenaline, is the neurotransmitter involved in our body’s “fight or flight” response. It provides our muscles the energy to respond quickly and more effectively when faced in a threat (4). Meanwhile, norepinephrine is the neurotransmitter also being referred to as the stress hormone. As the name implies, it is responsible for our body’s ability to respond to stress and is also involved in the “fight or flight” response. Norepinephrine increases a person’s breathing rate and heart rate thus, increasing blood circulation. And with an increase in blood flow, there will be more glucose and oxygen delivered to our working muscles as well as to our neurons in the brain (5). With Phenylalanine’s influence on the two neurotransmitters, there will be a boost in brain power and physical energy as well as an increase in metabolism and faster neuronal communication.

3. Phenylalanine for sleep

In recent studies, it has been found that Phenylalanine also serves to have influence in the production of Melatonin. Melatonin is a hormone involved in the regulation of our body’s circadian rhythm including sleep timing, blood pressure levels, and many other functions (6) and is highest between midnight and 8 in the morning. Because of this, proper sleeping patterns are promoted as well as the quality of sleep. As a result of having a good sleep, you will wake up feeling well-rested, and contented thus, affecting your overall mood and physical and cognitive performance for the whole day.

In contrast to the effects that Phenylalanine provides, a deficiency of this amino acid may be associated with stress, anxiety, depression and decreased energy levels both mentally and physically.

How do I maximize the effects of Phenylalanine?

1. Proper Phenylalanine dosage and frequency

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It is very crucial for any drug or supplement to be taken at the right amount and frequency for it to produce the desired effects while possibly eliminating or minimizing the undesired ones. With the case of Phenylalanine, how much of it do we really need each day? Basically, Phenylalanine seems to have a wide variety of effective dosages and a standard dose is yet to be established. However, most people recommend a daily dose of between 50 mg to 150 mg per day. This may then be divided and taken into multiple administrations if you wanted a more constant and sustained Phenylalanine benefits.

When starting with any new drug or supplement, it would be best to start off with the lowest possible dose to see how you respond and then gradually increasing it over time. You might also want to consider consulting your doctor or healthcare provider first since a person’s condition and health status may play a role.

Phenylalanine comes in capsule, tablet, or powder form and can even be used as a topical cream. Although they pose the same level of benefits, Phenylalanine capsule and tablet may be easier to administer. However if you wanted to save more from your money, you may consider buying Phenylalanine powder in bulk since it is cheaper in that way. (1)

2. Stacking Phenylalanine

Stacking has been a popular practice nowadays. This is done for the purpose of maximizing a drug’s potential and also, in order to yield more positive effects, to synergize each other, or to eliminate or minimize the side effects that the drugs may provide. With the case of Phenylalanine, what drugs and supplements are best to use in conjunction to it? If you wanted to have a more significant boost in your cognitive performance, then you may stack Phenylalanine with the Racetams. An example of which would be Phenylalanine and Pramiracetam stack. With this combination, you will have the cognitive boost to accomplish your mentally challenging tasks as well as the positive attitude and mood to perform them. With this, it will definitely lead you to higher productivity levels.

Having a thorough understanding of the drugs you wanted to have in a stack is important because some drugs might not go well with the others. Stacking supplements greatly depends on your needs and personal preferences however, it would be best to consult your doctor or healthcare provider first.

Phenylalanine Safety and Side Effects

Phenylalanine is considered to be safe to use and is well-tolerated. However, some people may respond differently and experience some Phenylalanine side effects. This may include headaches, nausea and heartburn. With doses taken at more than 5 g per day, Phenylalanine toxicity may occur and cause nerve damage. On the other hand, children may also experience anxiety, jitteriness and hyperactivity with Phenylalanine use.

Are there any contraindications to Phenylalanine use?

It is important to know that not all people are suitable to use Phenylalanine because of their condition or other medications that they are taking in. In this way, other possible side effects and drug interactions with Phenylalanine may be prevented. People who are taking Monoamine Oxidase Inhibitors (MAOIs) such as Marplan, should not take Phenylalanine supplement or any foods containing phenylalanine. This is because the two drugs interact and may cause a severe increase in blood pressure levels that may lead to heart or stroke. Moreover, Baclofen and Levodopa may reduce the absorption and effectiveness of Phenylalanine. Selegiline on the other hand, may strengthen the antidepressant effect of Phenylalanine and could disrupt one’s productivity levels. And lastly, antipsychotic drugs should not be used with Phenylalanine since the latter may worsen the former’s Tardive Dyskinesia side effect (1). Tardive Dyskinesia refers to a neurological disorder characterized by involuntary movements of the trunk, tongue, lips, face and extremities that is caused by long term treatment of antipsychotic medications. (2)


Where can I buy Phenylalanine?

You may purchase Phenylalanine online as it is available over the counter. Buy Phenylalanine from here and experience its variety of health benefits as outlined above.

References:
  1. http://umm.edu/health/medical/altmed/supplement/phenylalanine
  2. http://emedicine.medscape.com/article/1151826-overview
  3. http://www.news-medical.net/health/Dopamine-Functions.aspx
  4. http://www.news-medical.net/health/What-is-Epinephrine-%28Adrenaline%29.aspx
  5. http://study.com/academy/lesson/what-is-norepinephrine-effects-function-definition.html
  6. http://www.yourhormones.info/Hormones/Melatonin.aspx
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Results & Experiences

Daily Dosage # Stacks
500.00 mg 10
1500.00 mg 1
50.00 mg 1
3.00 mg 1
35.00 mg 1
100.00 mg 1
Duration # Stacks
20 days 1
Commonly Paired With # Stacks
AcetyLcarnitine 12
L-Theanine 10
Fish Oil 10
Bacopa monnieri 9
Vitamin D 9
Alpha GPC 9

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Wiki Last Updated: 2016-02-16