Oxiracetams is another drug of the racetam class that functions as a stimulant and is thought to be one of the best smart drugs under its classification. Although the drug is currently not approved by the FDA for the treatment of any conditions in the United States, researches show that it is safe to use even with high dosages and when taken in longer duration. It has been suggested that this drug may be beneficial for those with dementia and other neurodegenerative disorders. Those who take this drug tend to notice improvements in attention, memory, focus, orientation, and logic. One finding highlighted is that this drug was superior to that of piracetam among individuals with brain injuries and dementia.
Oxiracetam is categorized under Racetams.
It is also known as 4-hydroxy-2-oxo-pyrrolidinoacetamide, ISF-2522, Racetam.
Also Known4-hydroxy-2-oxo-pyrrolidinoacetamide, ISF-2522, Racetam
DescriptionOxiracetams is another drug of the racetam class that functions as a stimulant and is thought to be one of the best smart drugs under its classification. Although the drug is currently not approved by the FDA for the treatment of any conditions in the United States, researches show that it is safe to use even with high dosages and when taken in longer duration. It has been suggested that this drug may be beneficial for those with dementia and other neurodegenerative disorders. Those who take this drug tend to notice improvements in attention, memory, focus, orientation, and logic. One finding highlighted is that this drug was superior to that of piracetam among individuals with brain injuries and dementia.
Like all the other racetams, Oxiracetam may be strongly associated with headaches. However, it can be eliminated easily with the addition of Choline.
Oxiracetam Review: What is Oxiracetam?
The Energy Boosting Cognitive Enhancer
Oxiracectam serves to deliver a surge of cognitive benefits such as: an increased attention span, increased learning capacity, improved memory, increased mental energy, and cognitive processing power. Oxiracetam does not seem to affect Dopamine and Serotonin levels thus, it does not have any effect on one's mood and motivation. It is currently not approved by the FDA to be sold for medicinal purposes in the United States. It is a synthetic lab made molecule and not found or extracted from a natural source.
Despite its action towards cognition only, Oxiracetam demonstrates high levels of potency and is one of the more well-known nootropics by those starting to test out racetams. Dependency is not an issue with Oxiracetam as it is not addictive. However, tolerance may be an issue, based on user-submitted oxiracetam reviews. Patients like to cycle it to keep their bodies from building up a tolerance, all in all however, Oxiracetam has been observed among users to be "generally safe" and effective to use even on a long term basis. (1)
Oxiracetam Effects and Benefits
1. Improved Mental Performance
Just like many other nootropics under the Racetam family, Oxiracetam serves to influence the Cholinergic and Glutaminergic receptors. It directly modulates the production and increase in the levels of the neurotransmitters Acetylcholine and Gutamine, both of which are crucial to cognitive function. Acetylcholine, most specifically acts by increasing the brain’s ability to learn, and enhances one’s focus and motivation. Glutamine on the other hand, is associated with the formation of memory. (1)
With Oxiracetam influencing the release of these neurotransmitters, the user may expect an enhanced formation, storage, and retrieval of memory, improved attention and focus, an improved ability to think more efficiently, and generally a cognitive boost. It has been observed that Oxiracetam may benefit the person’s logical and technical thinking for the better, as well as the analytical reasoning. With all of these benefits, it can be seen as a effective tool to be used when studying or doing tasks related to Math and Engineering. (1)
2. Enhanced Neuronal Communication & Neuroprotection
The hippocampus benefits greatly from Oxiracetam's neuroprotective properties. It is the part in our brain responsible for the formation and retrieval of long term memory; thus there is an improvement in learning once the communication between neurons is improved. This is done by affecting the metabolism of lipids and through the stimulation of release of D-Asparctic acid (2).
Researchers have shown that Oxiracetam may also play a role as an antioxidant. It helps the brain protect and get rid of toxins that may harm it such as excess calcium. Also, further research and clinical studies need to be conducted regarding its possibility of being a treatment for brain damage associated with alcohol abuse and addiction. (3)
Maximizing the Effects of Oxiracetam
1. Start with the Right Dosage By now you are wondering how to take Oxiracetam, is it orally? or is it an injectable even. Firstly, we recommend the powder form (or capsulated) and secondly, it is vital for Oxiracetam to be taken at the right dose and frequency for it to produce the desired effects while potentially eliminating or minimizing the undesired ones. Oxiracetam dose ranges considerably from 600 mg to 2500 mg per day. It is best to look at the statistics below to see where and how much most user's are consuming.(1)
On the other hand, Oxiracetam may be taken at a frequency of 1 to 3 times per day. The total daily dose may be divided and taken in intervals- first dose may be taken early in the morning and the second one should not be later than midday, especially for those people having trouble falling and staying asleep as it is a psychostimulatory compound. Should you take Oxiracetam in multiple doses, remember that the second dose should not be more than about half of the first dose. (1)
When starting, it's best to start with lowest possible dose yielding the desired effects. Also, it is imperative for you to see and observe how you personally react to the drug, especially if you are a first-timer. Moreover, all users should consult their healthcare provider first for a suggested dosage and frequency since their condition and health status may play a role when taking this supplement. The Choline ratio to Oxiracetam should follow the original dosage required for choline, and increased or decreased based on how your body is feeling, it may take time to find the optimal dose, fear not, TrackMyStack can help you track and build the perfect stack.
Also, some suggest taking Oxiracetam an hour before an exam, presentation, or any activity that will require you heavy mental work. It is because after taking Oxiracetam, it get's absorbed into your body and crosses the blood-brain barrier. It reaches its peak levels in just a matter of 1 to 3 hours and has a half-life of approximately 8 to 10 hours (2). This is the total duration you will feel any sort of effect, but keep in mind as a racetam, the effects will not be "massively pro-found" like you would from something like noopept + alpha gpc or adrafinil.
2. Stacking Oxiracetam
Stacking this supplement is done for the purpose of maximizing the potential of Oxiracetam with other supplements. This is beneficial when it comes to compounding the beneficial effects, or to eliminate or minimize the side effects. Belonging to the family of Racetams, Oxiracetam is best stacked with Choline. However the one study that we found that discusses this, tested Phygostigmine, an acetylcholinesterase, and it provided no apparent benefits in mice (5). However user-reported data proves otherwise, as you can see below, user's had success augmenting Oxiracetam with differen't choline sources such as: Alpha GPC, Centrophenoxine and Citicoline. The general thinking is, as part of the racetam family it depletes choline and thus it is needed. The side effects of Oxiracetam may be prevented or minimized which include headache being the most common, along with nausea, dizziness, nervousness, dizziness, and insomnia (1).
Based on our stats charts below it can be noted that racetam such as the case of Oxiracetam and Aniracetam are often stacked together among other racetams. The thinking behind this is "you are covering all your bases" by supplementing other's such as noopept, pramiracetam, and piracetam. Aniracetam for example, is known to have a mood-enhancing anxiolytic effects while the former focuses more on the cognitive side, the users would expect a “mellow” feeling while remaining sharp mentally.
Aside from the suggested stack described earlier, Oxiracetam may also be paired with other potentially powerful nootropics. A lot of supplements may be chosen from including L-Theanine and Caffeine. Stacking different supplements may help you with your own personal needs as to cognitive function, mood and emotional function. Check out the link above for Oxiracetam stacks, and additionally you may also perform a "Oxiracetam vs." search from the right to compare it side by side with other "smart drugs" you may be taking such as Adderall or Ritalin.
The Sweet Taste of Oxiracetam
If you are about consume Oxiracetam in powder form, and if it is of good quality, and from a reliable source like the one mentioned below, you will find that it has a "sweet taste". If it is bitter, it may be not be as potent or of quality as you may want want it to be. The same goes with having it taste "like a chemical". This is the opposite of what you will taste when it comes to Aniracetam or Piracetam. A sweet taste is one thing, but you may notice that it still smells pretty bad!
Where To Buy Oxiracetam
A source we recommend is PowderCity which has COA available and always has sales going on for different smart powders. It is available over the counter and thus you do not need any prescription from your family doctor in order to purchase. It is advisable that you print out this page as a quick reference for the dosage, condition and reference for your care provider and yourself. This page may also be beneficial for them to quickly learn and advise you on if you should go ahead with using Oxiracetam for your goals. This page provides more up-front statistical information based on experiences that can be used right away then a reddit, erowid, or wiki article for example.
Oxiracetam is readily available in powder form although some sources also have the pre-measured capsules if you find the former type quite uncomfortable to use. Since Oxiracetam is a water-soluble nootropic, you can easily mix and drink it with water. Consider buying bulk Oxiracetam powder with choline if you intend on using it for a while and to get a discount. Powdercity ships to Canada, UK, India, Australia, USA and provides tracking so you are in good hands. Buy Oxiracetam now and quickly notice a significant step up in your cognitive function. To share more information leave a comment below or discuss it in our community forum.