Huperzine A, also called selagine, is an alkaloid compound commonly used to treat Alzheimer's disease and other neurodegenerative diseases. It is known for its ability to improve memory and cognitive abilities by increasing acetylcholine levels in the brain and by blocking the action of cholinesterase. This is particularly effective when studying or trying to learn any new material. Also, it acts as an antagonist of the NMDA receptor and has neuroprotective properties by protecting neurons from damage due to glutamate, peroxides, and beta-amyloids. However, it cannot be medically endorsed as a treatment until additional research is conducted.
Huperzine A is categorized under Acetylcholinesterase Inhibitors.
It is also known as 1R, 9S, 13E-1-amino-13-ethylidene-11-methyl-6-azatricyclo- [184.108.40.206 2, 7 ]trideca-27, 3, 10-trien-5-on, Qian Ceng Ta Huperzia Serrata.
Also Known 1R, 9S, 13E-1-amino-13-ethylidene-11-methyl-6-azatricyclo- [220.127.116.11 2, 7 ]trideca-27, 3, 10-trien-5-on, Qian Ceng Ta Huperzia Serrata
DescriptionHuperzine A, also called selagine, is an alkaloid compound commonly used to treat Alzheimer's disease and other neurodegenerative diseases. It is known for its ability to improve memory and cognitive abilities by increasing acetylcholine levels in the brain and by blocking the action of cholinesterase. This is particularly effective when studying or trying to learn any new material. Also, it acts as an antagonist of the NMDA receptor and has neuroprotective properties by protecting neurons from damage due to glutamate, peroxides, and beta-amyloids. However, it cannot be medically endorsed as a treatment until additional research is conducted.
Huperzine A appears to be safe even with daily use. However, occasional symptoms include digestive upset, nausea, vomiting, and diarrhea. Also, if taken in excessively large dosage, it can cause slurred speech, muscle twitching, drooling, incontinence, elevated blood pressure, and a slow heart rate.
Huperzine A Review: What is Huperzine A?
Huperzine A - The Potent Natural Nootropic
Are you looking for an excellent study aid that serves to have long-lasting effects? Not only is it a natural nootropic compound but it also promotes a healthy brain and improved neuronal communication. Huperzine A, a natural supplement derived from club moss, is one of the most potent nootropics at the present time. It is known not only for the cognitive enhancement it provides but also, is one of the most studied drugs due to a very promising treatment to cognitive problems, specifically Alzheimer’s disease and dementia.
Let us now look what Huperzine has to offer to us and know why it is so potent in delivering its benefits.
What are the benefits of Huperzine A and its mechanism of action?
Basically, Huperzine A works just like that of the Racetams, it serves to influence the Cholinergic system and increases the level of Acetylcholine. And as we all know, this important neurotransmitter is strongly associated with an individual’s memory and cognitive functioning. However, the difference lies in that Huperzine A acts as an Acetylcholinesterase inhibitor. Meaning to say, it stops or inhibits the action of Acetylcholinesterase, the enzyme responsible breaking down Acetylcholine. Because of this, it indirectly increases the levels of the neurotransmitter. In contrast to that, the Racetams do not acts as an inhibitor to the enzyme instead, it directly increases Acetylcholine levels. Because of this mechanism, the user may experience an enhanced cognitive function specifically that of memory formation and retrieval and consolidation.
Moreover, Huperzine A serves to be of great benefit for those individuals suffering from cognitive decline such as that of dementia and Alzheimer’s disease. Aside from positively influencing the cholinergic system, this benefit may be attributed with Huperzine A acting on NGF or Nerve Growth Factor. The nootropic increases the levels of the said compound which is believed to help in the formation of new nerve cells. Moreover, Huperzine A improves communication between neurons. As a result, there would be improvement in one’s cognitive functioning. (2)
In relation to Huperzine A and Alzheimer’s disease, several studies have been conducted and showed promising results. Patients who received Huperzine A treatment showed improvement in their memory and ability to think. In individuals with no cognitive decline, Huperzine A improved their memory formation and retention. (1)
Also, Huperzine A appears to be neuroprotective. It protects the brain from toxins and damaging compounds. Because of this, it promotes a healthy brain and proper brain functioning. (3)
How do I maximize Huperzine A effects?
1. Proper Huperzine A dosage, mode of administration and frequency
It is very crucial for any drug or supplement to be taken at the right amount and frequency for it to produce the desired effects while possibly eliminating or minimizing the undesired ones. With regards to Huperzine A, how much of it do we really need to achieve maximum benefits? Basically, Huperzine A may be administered in two ways- either orally or intravenously. The use of the intravenous Huperzine A method is done for individuals with muscle weakness and the appropriate dosage and administration is given by the authorized healthcare professional. On the other hand, oral Huperzine A is generally recommended between doses 50 to 200 mcg and is taken twice a day. This natural nootropic requires a much lesser dosage compared to other drugs because it is highly potent and powerful. For the treatment of Alzheimer’s disease, a dose of up to 400 mcg may be taken (2). Moreover for the geriatric population, the recommended dosage would be 30 mcg and taken twice daily. (1)
To avoid physical habituation, experts recommend that Huperzine A be taken in cycles such as taking it for 3 weeks then cycling it off for about a week. It can be taken alone without the presence of food and can still be easily absorbed in the gut.
However, we should take note that it would be best to start with the lowest possible dose yielding the desired effects. Also, it is imperative for you to see and observe how you personally react to the drug, especially if you are a first-timer. Moreover, some people may also need to consult their healthcare provider first for their suggested Huperzine A dosage and frequency since their condition and health status may play a role when taking some medications.
2. Stacking Huperzine A
Stacking has been a popular practice nowadays. This is done for the purpose of maximizing a drug’s potential and also, in order to yield more positive effects, to synergize each other, or to eliminate or minimize the side effects that the drugs may provide. With the case of Huperzine A, what are the drugs and supplements that would make a great combination to it? A popular and powerful stack today would be the Huperzine A and Noopept stack. Both nootropics are known to be potent and shows higher bioavailability compared to other drugs. They synergize the effects of each other and as a result, the stack will do wonders with regards to one’s cognitive performance. Moreover, since Noopept's effects may be experienced 15 minutes following its ingestion, the stack would provide a significant kick off to your brain’s function. On the other hand due to Huperzine A’s long half-life of approximately 10 to 14 hours, there would be a sustained release of positive effects needed for the long hours of your cognitive performance (3). With the Huperzine A- Noopept stack, this will be of great help as a study aid as well as for individuals who wanted a step up in their leaning abilities.
Another stack that would be of great benefit is the Huperzine A and Choline stack. Since Huperzine A is an acetylcholinesterase inhibitor, the supplementation of a quality source of Choline can further increase Acetylcholine levels and as a result, may greatly potentiate the action of the former and yield greater cognitive results. Some quality sources of choline include Alpha GPC, Centrophenoxine, Citicoline and among many others.
Huperzine A safety
Generally, Huperzine A is considered safe to use when taken at the recommended dose. However, some individuals may be sensitive and respond quite differently from others. Because of this, some Huperzine A side effects may be encountered. Although considered as mild, Huperzine A may produce headaches, nausea, vomiting, sweating, restlessness, diarrhea, increased saliva, high blood pressure, and muscle twitching. When these effects are experienced, stop Huperzine A use and consult your doctor and healthcare provider for proper advice. (1)
Where can I buy Huperzine A?
Some sources where you may purchase your Huperzine A include Amazon.com, PowderCity.com, among others. It is available over the counter, you do not need any prescription from your doctor in order to purchase it. It is readily available in powder or tablet form. The tablets seem to be more convenient and come in 100 mcg and 200 mcg doses while the Huperzine A powder is cheaper and can be bought in bulk orders. Buy Huperzine A now and quickly notice a significant step up in your cognitive function. BUY HUPERZINE A NOW