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DMAE

DMAE Dosage & Review

DMAE Review DMAE, also known as dimethylaminoethanol or Deanol is an alcohol produced inside the human brain. It could also be obtained from food sources like fish. It's believed that DMAE is needed for building choline thus enhancing cognitive function through improved communication between neurons. In many studies, DMAE has improved alertness, vigilance and also improved mood in people with emotional issues such as ADHD, Alzheimer's disease, Autism, and Tardive Dyskinesia. DMAE is categorized under Cholinergics. It is also known as Dimethylaminoethanol, dimethylethanolamine, Deanol cream.
DMAE
Also Known Dimethylaminoethanol, dimethylethanolamine, Deanol cream
Description DMAE, also known as dimethylaminoethanol or Deanol is an alcohol produced inside the human brain. It could also be obtained from food sources like fish. It's believed that DMAE is needed for building choline thus enhancing cognitive function through improved communication between neurons. In many studies, DMAE has improved alertness, vigilance and also improved mood in people with emotional issues such as ADHD, Alzheimer's disease, Autism, and Tardive Dyskinesia.
Typical Dose 300mg to 2000mg daily. Taken 1-3 times.
Stacks
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Benefits and Effectiveness



DMAE Dosage

300mg to 2000mg daily. Taken 1-3 times.

Side Effects

Generally safe for use when it is used orally or topically. May cause constipation, urticaria, headache, drowsiness, or insomnia. Some contraindications to DMAE use include those individuals suffering from bipolar forms of depression, epilepsy, Parkinson's Disease, and seizures. Pregnant or nursing mothers are also not encouraged to use this supplement.

DMAE Review: What is DMAE?

Dimethylaminoethanol, also called as DMAE, is an amino acid naturally found within the body. It is considered to be an analog of B Vitamin and is produced in the human brain tissue in minute amounts (1). Some food sources that contain DMAE include salmon, anchovies and sardines. Our dietary intake of DMAE may not be sufficient enough, thus, supplementation of this compound is gradually gaining popularity.

Although it is structurally similar to Choline, DMAE contains two methyl molecules while as Choline has three. Because of this, DMAE can pass the BBB and can start its cascade of events to deliver its benefits. On the other hand, DMAE is marketed as a prescription drug in Europe. It is sold as Deanol or Deaner to treat behavior problems and memory deficits and learning difficulties such as Alzheimer's disease. Moreover, you might also want to consider trying the prodrug of DMAE which is Centrophenoxine. (2)


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What are the benefits of taking DMAE?

DMAE can be supplemented for various purposes ranging from cognitive enhancement, improved athletic performance to anti-aging. We list the 6 benefits of supplementing it below:

DMAE for Enhanced Cognitive Function
DMAE is seen as one of the top choline sources available, and it influences our brain's cholinergic system. Which just means DMAE is good at increasing Acetylcholine levels in the brain. Acetylcholine is the neurotransmitter responsible for an individual's memory, learning and mood. Moreover, it also plays a vital role on one's contraction of muscles, the regulation of the endocrine system, and REM or Rapid Eye Movement sleep cycles (3). Because DMAE increases the activity of Acetylcholine, it may result in enhanced cognition. This includes improved attention span and focus, and faster processing speed.

Because of this mechanism of action, it is used as a treatment for conditions involving memory deficits, learning difficulties, and other cognitive problems. On the other hand as we age, the levels of DMAE in our brain gradually decreases which may leading to cognitive deficits. Thus, Supplementation of DMAE would beneficial to ensure optimal brain function as we age. Users claim that there is a build up time of 1 to 2 weeks to feel optimal results and that stacking it with Vitamin B5 helps potentiate it's effects in the brain.

DMAE and Energy Metabolism
It has also been found that DMAE boosts brain power through increased blood circulation in one's brain. But how is brain power correlated to blood flow? Blood carries oxygen and nutrients to our brain cells to provide nourishment which helps your brain run smoothly. Additionally, blood provides our cells glucose for energy and so with an increase in blood circulation, there wil

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Because of this mechanism of action, it is used as a treatment for conditions involving memory deficits, learning difficulties, and other cognitive problems. On the other hand as we age, the levels of DMAE in our brain gradually decreases which may leading to cognitive deficits. Thus, Supplementation of DMAE would beneficial to ensure optimal brain function as we age. Users claim that there is a build up time of 1 to 2 weeks to feel optimal results and that stacking it with Vitamin B5 helps potentiate it's effects in the brain.

DMAE and Energy Metabolism
It has also been found that DMAE boosts brain power through increased blood circulation in one's brain. But how is brain power correlated to blood flow? Blood carries oxygen and nutrients to our brain cells to provide nourishment which helps your brain run smoothly. Additionally, blood provides our cells glucose for energy and so with an increase in blood circulation, there will be an increased supply of energy available for mentally demanding tasks.

DMAE and its Anti-Aging Properties
Given that DMAE is a powerful nootropic, one of the most intriguing properties of DMAE would be its anti-aging benefits. Researchers believe that DMAE works in several ways to improve one's skin. Firstly, it slows down the production of arachidonic acid- a polyunsaturated omega-6 fatty acid. In this way, there would be a reduction of wrinkles and could slow the process and signs of aging. Second, DMAE acts by reducing the accumulation of lipofuscin deposits inside the skin cells. It also removes the lipofuscin deposits within the brain. Lastly, DMAE serves to stabilize the cell membranes of skin cells, for this you would need to use the topical creams available. Because of this mechanism of action, DMAE is good at improving skin tone and firmness of skin. It will make you look younger, blemish free, and reduces inflammation. Studies also show that DMAE could possibly improve underlying facial muscle tone.

DMAE for Brain Health
Another interesting benefit of DMAE includes its antioxidant properties. As an antioxidant, it protects neurons from oxidation and other damaging compounds. As a result, this ensures the health and integrity of our nerve cells. DMAE binds to phospholipids in the brain and in the nerve membranes. Through this there is an increase in membrane fluidity and permeability. This is important because cell membranes play a vital role in the transportation of nutrients and removal of unwanted waste products. In addition, cell membrane fluidity declines as we age, so it would be best to take DMAE to preserve and improve this function. The results you will get from this (I didn't as I am not that older rather) but the results would be improved communication between neurons.

Anti-Anxiety or Anxiolytic effect of DMAE
Studies claim that DMAE also has its fair share of anxiolytic effects. On a study conducted among students shows that taking DMAE can reduce the levels of stress and anxiety and leaves you in a better mood.

DMAE is Beneficial for Bodybuilding
A lot of athletes, body builders, and other active individuals have sought for DMAE as an excellent addition to their pre-workout formulas. This is because DMAE increases focus, mental tolerance and stamina as well.

How much DMAE should you take Daily?

It is crucial to take the right dose at the right time daily, however these variables differ for every individual. Generally, the dosage of DMAE is fairly wide since it is also used for many reasons. The most commonly used dose ranges from 300 mg to 1200 mg daily. This dose may be divided and taken into multiple administrations in a day for a more constant and sustained release of effects. Generally we recommend that when starting with a new drug or supplement, it would be best to start off with a low dose to see how you respond and then gradually increase it over time. It would be best to start with a dose of 150 mg daily and observe the results. You might also want to consider consulting your doctor or healthcare provider first as any underlying condition may cause an adverse reaction.

Where to buy DMAE Online

You can purchase DMAE online/ over the counter as it is a non-controlled substance. DMAE is mostly found in pill form, some specialty retailers may carry it in powder form. You can buy our pick which is number one this page now and get it within a few days. Remember to give it a few days, take the right dose and order the bioavailable/potent version and take it with Vitamin B5 for it to potentiate better.

References:
  1. http://www.ncbi.nlm.nih.gov/pubmed/15675889
  2. http://www.webmd.com/vitamins-supplements/ingredientmono-524-dmae%20(deanol).aspx?activeingredientid=524&activeingredientname=dmae%20(deanol)
  3. http://www.chemistryexplained.com/A-Ar/Acetylcholine.html
Reviewer: Kathleen R. RN, PT
Wiki Last Updated: 2016-10-11
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Results & Experiences

Daily Dosage # Stacks
350.00 mg 5
250.00 mg 5
300.00 mg 3
351.00 mg 2
200.00 mg 2
400.00 mg 2
100.00 mg 2
5.00 mg 1
500.00 mg 1
3.00 mg 1
Purpose # Stacks Effectiveness
Problems concentrating 1
Unknown
Can't tell
None
Slight
Moderate
Major
Fatigue 1
Unknown
Can't tell
None
Slight
Moderate
Major
Lack of motivation 1
Unknown
Can't tell
None
Slight
Moderate
Major
Side Effects # Stacks
Fatigue 1
Commonly Paired With # Stacks
Noopept 15
Fish Oil 14
Alpha GPC 14
L-Theanine 14
AcetylCarnitine 13
Huperzine A 10

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