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Piracetam vs Oxiracetam

Piracetam vs Oxiracetam Comparison, Similarities & Differences


Read full Piracetam Review


Read our Piracetam Review

Piracetam is the first compound developed under the racetam class and was synthetically created by Belgium lab UCB Pharma. Of the racetam class, this is perhaps the most discussed and utilized nootropic. Its mechanism of action is poorly understood, but many speculate that it improves cognition without stimulating or sedating properties. In other words, it doesn't seem to affect a person's arousal. It is a modulator of the AMPA receptor and may work on various ion channels within the brain to excite neurons. Additionally, it improves acetylcholine functioning and may influence NMDA glutamate receptors. There is some evidence that it increases the amount of blood flow and oxygen to the brain. It is not approved in the United States for any condition, but is approved in the United Kingdom. In recent years it has gained popularity among students as a way to increase academic performance.

Oxiracetams is another drug of the racetam class that functions as a stimulant and is thought to be one of the best smart drugs under its classification. Although the drug is currently not approved by the FDA for the treatment of any conditions in the United States, researches show that it is safe to use even with high dosages and when taken in longer duration. It has been suggested that this drug may be beneficial for those with dementia and other neurodegenerative disorders. Those who take this drug tend to notice improvements in attention, memory, focus, orientation, and logic. One finding highlighted is that this drug was superior to that of piracetam among individuals with brain injuries and dementia.


Pyracetam, Pyrrolidone acetamide, 2-Oxo-1-pyrrolidine, Memotopril, Fezam with cinnarizine, UCB6215

4-hydroxy-2-oxo-pyrrolidinoacetamide, ISF-2522, Racetam


4.8 g daily/2x dose. 40-100mg/kg.
Daily Dosage # Stacks
800.00 mg 7
2.00 g 7
1600.00 mg 6
3.00 g 5
2.40 g 5
4.80 g 5
250.00 mg 4
1200.00 mg 4
2400.00 mg 3
1.60 g 2

Daily Dosage # Stacks
750.00 mg 16
800.00 mg 4
250.00 mg 3
1000.00 mg 2
1400.00 mg 2
600.00 mg 2
500.00 mg 2
1500.00 mg 1
375.00 mg 1
100.00 mg 1

Side Effects

Like all the other racetams, Piracetam may be strongly associated with headaches. However, it can be eliminated easily with the addition of Choline.

Like all the other racetams, Oxiracetam may be strongly associated with headaches. However, it can be eliminated easily with the addition of Choline.


Total Users

There are over 86 users currently taking this supplement.

There are over 51 users currently taking this supplement.


3.00/5 based on 3 user votes

4.00/5 based on 5 user votes

Evidence-Based Effects

  • Cognitive Decline - Decreased
  • Memory - Increased

  • Cognitive Decline - Decreased
  • Memory - Increased
  • Quality of Life (aka QOL) - Increased
  • Verbal Fluency - Increased

Similar Comparisons

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No data available

Medical Conditions

Medical Symptoms

Medical Symptoms # Stacks
Fatigue 2
Brain fog 1
Sweating excessive 1

No data available


No data available

Commonly Paired With

Commonly Paired With # Stacks
Fish Oil 43
Noopept 36
L-Theanine 36
Alpha GPC 34
Citicoline (CDP-Choline) 20
AcetylCarnitine 18

Commonly Paired With # Stacks
Noopept 32
Alpha GPC 32
L-Theanine 31
Fish Oil 23
Aniracetam 20
Phenylpiracetam 19

Price & Brand

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