|Cognition||8||Ginkgo biloba, AcetylCarnitine, Noopept, Phosphatidylserine, Modafinil (Provigil), L-Theanine, Citicoline (CDP-Choline), Alpha GPC|
|Memory||6||Ginkgo biloba, Polygala Tenuifolia, Noopept, Phosphatidylserine, Fish Oil, Modafinil (Provigil), Citicoline (CDP-Choline)|
|Insulin Sensitivity||5||Magnesium, Curcumin, Inositol, Vitamin D, AcetylCarnitine, Fish Oil|
|Attention||4||Ginkgo biloba, AcetylCarnitine, Phosphatidylserine, Fish Oil, Modafinil (Provigil), Citicoline (CDP-Choline)|
|Working Memory||3||Ginkgo biloba, Coconut Oil, Polygala Tenuifolia, Phosphatidylserine, Modafinil (Provigil)|
|Lean Mass||2||Vitamin D, AcetylCarnitine, Fish Oil|
|Anaerobic Exercise||2||AcetylCarnitine, Phosphatidylserine|
|Calmness||2||Ginkgo biloba, Modafinil (Provigil), L-Theanine|
|Sperm Quality||2||AcetylCarnitine, Shilajit|
|Sleep Quality||2||Magnesium, Ginkgo biloba, Lions Mane|
|HDL-C||2||Magnesium, Curcumin, Inositol, AcetylCarnitine|
|Free Testosterone||2||Magnesium, Vitamin D, AcetylCarnitine, Shilajit, Phosphatidylserine, Fish Oil|
|Cell Adhesion Factors (aka sCAM-1||1||Fish Oil|
|Blood Flow||1||Ginkgo biloba, Fish Oil|
|Endothelial Function||1||Fish Oil|
|Power Output||1||Vitamin D, AcetylCarnitine, Alpha GPC|
|Ocular Blood Flow||1||Ginkgo biloba|
|Muscle Carnitine Content||1||AcetylCarnitine|
|Treatment of Hepatic Encephalopathy||1||AcetylCarnitine|
|Infant Birth Weight||1||Fish Oil|
|Growth Hormone||1||Alpha GPC|
|Anti-Oxidant Enzyme Profile||1||Curcumin|
|Stroke Recovery Rate||Neutral||Ginkgo biloba|
|B cell count||Neutral||Fish Oil|
|Verbal Fluency||Neutral||Ginkgo biloba, Polygala Tenuifolia|
|Apolipoprotein B||Neutral||Fish Oil|
|Insulin Secretion||Neutral||Fish Oil|
|Symptoms of Tinnitus||Neutral||Ginkgo biloba|
|Symptoms of Schizophrenia||Neutral||Inositol|
|Postpartum Depression||Neutral||Fish Oil|
|Pre-Eclampsia Risk||Neutral||Fish Oil|
|VO2 Max||Neutral||Curcumin, AcetylCarnitine, Fish Oil|
|Total Cholesterol||Neutral||Curcumin, AcetylCarnitine|
|Natural Killer Cell Content (aka NK cell||Neutral||Fish Oil|
|Muscle Soreness (aka Delayed onset muscle soreness||Neutral||Fish Oil|
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500mcg x 1/day subcutaneous injection (N-Acetyl Semax Amidate). In animals, Semax rapidly elevates the levels and expression of NGF, BDNF, and its signaling receptor TrkB in the hippocampus. It rapidly activates serotonergic and dopaminergic brain systems. It has been found to produce antidepressant-like and anxiolytic-like effects, as well as attenuate the behavioral effects of exposure to chronic stress.* N-Acetyl Semax Amidate is an experimental version of Semax which is acetylated to increase permeability across the blood-brain barrier and amidated to protect the peptide from enzymatic degradation.
Bulk powders complete multivitamins
300mg x 1/day. Root powder, also known as Solomon's Seal. Increases NGF & BDNF.* Used for thousands of years for its healing and restorative potential.
300mg x 1/day. Root powder of the Bonnet Bellflower. Increases NGF & BDNF. Inhibits the acetylcholinesterase (AChE) enzyme from breaking down acetylcholine. Increases phosphorylated cAMP response element binding protein (p-CREB), resulting in improving long-term memory.*
100mg x 1 in morning as needed (approx. 1-2/week). Structurally similar to Caffeine, preliminary evidence suggests that it activates similar signalling pathways. Evidence suggests less tolerance with theacrine than caffeine. May have stress reducing properties at low doses.
Exercise appears to boost the size of the hippocampus (the brain area involved in verbal memory and learning), increase mitochondrial biogenesis, and increase BDNF.* If you're considering taking unproven supplements or research chemicals, then consider regular exercise as well (since it's likely safer, cheaper, synergetic, and effective).
667mg x 3/day. Increases BDNF. Bioavailable form of Magnesium (Mg) which crosses the blood-brain barrier (BBB), shown to improve memory in normal and aging animals. Also protects cognitive function and synaptic plasticity.*
|20 mg||Pyrroloquinoline Quinone (Bio PQQ)||,,,,,,||2016-06-07|
20mg x 1/day (Pyrroloquinoline Quinone Disodium Salt, also known as "BioPQQ"). Stimulates NGF synthesis and secretion, as well as mitochondrial biogenesis.*
500mg x 1/day (Extract from Turmeric). Increases BDNF. Neuroprotective against certain types of induced neuronal cell death. Synergistic with Fish Oil's anti-inflammatory effects.*
2g x 2/day (myo-inositol). Reported to reverse desensitization of serotonin receptors and significantly reduced scores of OCD symptoms compared with placebo.* Inositol is a carbohydrate that's half as sweet as sugar, so I use it in lieu of sugar in hot tea. Gradually increasing dosage reduces gastrointestinal side-effects.
500mg x 1/day (Ginkgo Biloba 4:1 Extract). Improves expression of NGF, BDNF, and Neurotrophin-3 (NT-3). NT-3 stimulates nerve growth in neurons that are not affected by NGF. Increases uptake of serotonin into neurons. Shown to be capable of producing improvement in memory and attention in healthy individuals.* (Discontinued on 10/09/15 due to allergy)
1000mg x 1 capsule taken once per week. As recommended in "The Depression Cure" book by Stephen Ilardi Ph.D. as a Gamma-Linolenic Acid (GLA) source.*
100mg x 1/day. Present primarily in the mitochondria, it is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of adenosine triphosphate (ATP). Protects from free radical damage.
2-4 tbsp. per day, used as cooking oil and/or added to food. Ketone bodies, such as those found in the medium chain triglycerides (MCTs) in coconut fat, are an effective alternative energy substrate for the brain.*
500mg x 2/day (Centella Asiatica Extract 5% Saponin). Enhances the activities of NGF and increases BDNF. Increases connections between neurons (dendritic branching). Neuroprotective and regenerates damaged neurons. Improves memory, mood, and attention while lowering anxiety.*
5000iu x 1/day. Increases NGF. Low Vitamin D concentrations may increase the risk of cognitive decline.* Recently reduced from a year of daily 10000iu supplementation due to finally increasing Vitamin D blood lab results well within "normal" range.
400mg x 1/day. Increases mitochondrial biogenesis.* Alpha Lipoic Acid (ALA) is an antioxidant made by the body found in every cell, where it helps turn glucose into energy. Commonly combined synergistically with Acetyl-L-Carnitine (ALCAR).
1000mcg (1mL) x 1/month subcutaneous injection (Cyanocobalamin Vitamin B12). Increases BDNF when combined with Fish Oil for treating Vitamin B12 and Omega-3 deficiency. Vitamin B12 deficiency presents as nonspecific symptoms of fatigue, lassitude, malaise, vertigo, and cognitive impairment that could be attributed to aging.*
1/day (30 billion live cultures per capsule). Poorer gut health is correlated with more severe neurological and cognitive deficits such as nervousness, memory loss, forgetfulness, and confusion.*
250mg x 1/day. Acetyl-L-Carnitine (ALCAR) increases NGF in the hippocampus and energy production in the mitochondria. Increases choline acetyltransferase (ChAT) activity, an enzyme involved in acetylcholine synthesis.* ALCAR is a powerful antioxidant and neuro-protective agent.
500mg x 1/day (5:1 Extract). Shown to increase NGF.*
200mg x 2/day. Synergetic with Coenzyme Q10 to speed and augment electron transfer within mitochondria, increasing cellular energy.* (Temporarily discontinued as of 12/6 due to supplier out of stock)
300mg x 1/day (Root 5:1 Extract Powder). Increases NGF & BDNF. Improves learning and memory by preventing reductions in brain neurotransmitter levels including noradrenaline. Increases choline acetyltransferase (ChAT), an enzyme involved in acetylcholine (ACh) synthesis. Has fast acting antidepressive effects by hindering NMDA receptor signalling.*
300mg x 1/day. Enhances NGF-mediated neurite outgrowth and synaptogenesis (formation of synapses between neurons).*
15mg x 1/day. Increases NGF and BDNF in the hippocampus.* Peptide that is regarded as one of the most effective and strongest of all the nootropic supplements, suggested to be up to 1000x more powerful than Piracetam.
300mg x 1/day (Uridine Monophosphate). Enhances the neurite outgrowth produced by NGF. Increases acetylcholine (ACh) level and release. Modulates stimulant-induced release of dopamine. Synergistic with choline to improve cognitive deficits.*
200mg x 1/day. Naturally found in fish, phosphatydilserine (PS) is one of the phospholipids which play an important functional role in membrane-related processes in the brain.*
1 x 1000 mg taken 2/day with meals (The Vitamin Shoppe "Omega 3 Fish Oil"). DHA such as found in Fish Oil increases BDNF. Each of this brand's capsules contain 840mg EPA/DHA for 1680mg total EPA/DHA per day. Necessary to optimizing balance of Omega-3/Omega-6 long-chain polyunsaturated fatty acid ratio for proper neurodevelopment and cognitive functions.*
100mg x 1/day. Stimulator of NGF synthesis.* Transporter in the electron transport chain of mitochondria and increases the production of adenosine triphosphate (ATP). Promoted commercially as a synthetic analog of Coenzyme Q10.
10mg x 1/day. Active component and extract of Black Pepper, inhibits glucuronidation in the liver which would prevent uptake of certain supplements. Piperine increases the bioavailability of Curcumin by 2000% and Coenzyme Q10 by 30%. It reverses corticosterone induced reduction in BDNF mRNA expression in cultured hippocampal neurons.*
1g x 2/day. Using Lion's Mane Mushroom (hericium erinaceus) 10x water/ethanol extract powder. Promotes NGF gene expression and synthesis in the brain.*
2 cup x 2-4/day. I switch to decaf in the afternoons or when I want to minimize caffeine. Shown to potentiate NGF-induced neuritogenesis (formation of neurites).*
25mg x 1/day in morning (or up to 100mg as needed for wakefulness). Wakefulness-promoting agent (or eugeroic) used off-label by those wishing to avoid fatigue. In healthy individuals, improves some aspects of working memory, such as digit span, digit manipulation and pattern recognition memory. Modafinil is a prescription drug indicated for narcolepsy and shift work sleep disorder. It was developed from Adrafinil which is available as a supplement with similar effects (I prefer Modafinil).* When taking in conjunction with N-Acetyl Semax Amidate, I will take no more than a 100mg dose due to possible increase of blood pressure.
350mg x 1/day (Dimethylaminoethanol Bitartrate providing approx. 37% DMAE). Antioxidant naturally found in fish. A precursor of choline, which in turn allows the brain to optimize the production of acetylcholine (ACh) that is a primary neurotransmitter involved in learning and memory. Was used to treat ADHD (improve focus) in the 60's and 70's, with positive results comparable to Ritalin.*
300mg x 1/day. Increases the levels of the neurotransmitter acetylcholine (ACh) in the brain, improving memory and communication between neurons.
300mg x 1/day (Alpha-GPC 50% Powder). Increases the levels of the neurotransmitter acetylcholine (ACh) in the brain, improving memory and communication between neurons. Taking in conjunction with equal amount of Citicoline.
Cognitive Enhancement Starter
Use te stack to increase energy, focus and memory.
Cognitive Enhancement Monday
Mondays Nootropics (w powerlifting day)