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Memory boost

Cognitive Enhancement 359 Updated: 2016-10-12 Matt.moody
I have trouble memorizing everyday people and things.

405 Potential Effects from this Stack

Effect OnScaleContributors
Cognition15 Resveratrol, Pycnogenol, Ginkgo biloba, Tyrosine, Phosphatidylserine, Modafinil (Provigil), Choline Bitartrate, Rhodiola Rosea, Citicoline (CDP-Choline), Phenylpiracetam, Bacopa monnieri, Aniracetam, AcetylCarnitine, Zinc, Noopept, Alpha GPC, L-Theanine
Memory12 Ginger, Ginkgo biloba, Phosphatidylserine, Vinpocetine, Modafinil (Provigil), Oxiracetam, Citicoline (CDP-Choline), Phenylpiracetam, Creatine, Piracetam, Bacopa monnieri, Aniracetam, Vitamin E, Noopept, Fish Oil
Insulin Sensitivity8 Resveratrol, Conjugated Linoleic Acid, Whey Protein, Vitamin K, Inositol, Creatine, Vitamin E, AcetylCarnitine, Vitamin C, Zinc, Vitamin D, Magnesium, Fish Oil
Lean Mass5 Conjugated Linoleic Acid, Whey Protein, Creatine, AcetylCarnitine, Vitamin D, Fish Oil
Attention5 Pycnogenol, Ginkgo biloba, Phosphatidylserine, Modafinil (Provigil), Rhodiola Rosea, Citicoline (CDP-Choline), Creatine, Bacopa monnieri, AcetylCarnitine, Fish Oil
Blood Flow4 Pycnogenol, Ginkgo biloba, Vitamin E, Vitamin C, Fish Oil
Anaerobic Exercise4 Resveratrol, Taurine, Phosphatidylserine, Creatine, Ashwagandha, AcetylCarnitine
Free Testosterone4 Phosphatidylserine, Creatine, Ashwagandha, Vitamin E, AcetylCarnitine, Zinc, Vitamin D, Magnesium, Fish Oil
Sleep Quality3 GABA, Lions Mane, Ginkgo biloba, Magnesium
Working Memory3 Ginkgo biloba, Tyrosine, Phosphatidylserine, Modafinil (Provigil)
Sperm Quality3 Ashwagandha, AcetylCarnitine, Vitamin C
Euphoric3 Ginkgo biloba, Rhodiola Rosea, Creatine, Vitamin E
Power Output2 Resveratrol, Whey Protein, Rhodiola Rosea, Creatine, Ashwagandha, AcetylCarnitine, Vitamin D, Alpha GPC
Motivation2 Modafinil (Provigil), Ashwagandha
Growth Hormone2 Creatine, Alpha GPC
Calmness2 Ginkgo biloba, Modafinil (Provigil), L-Theanine
Quality of Life (aka QOL)1 Oxiracetam
Skin dryness1 Vitamin A
Muscle Carnitine Content1 AcetylCarnitine
Alertness1 Modafinil (Provigil)
HDL-C1 Inositol, Vitamin E, AcetylCarnitine, Magnesium
Ocular Blood Flow1 Ginkgo biloba
Verbal Fluency1 Ginkgo biloba, Oxiracetam, Vitamin E
Infant Birth Weight1 Fish Oil
Skin pigmentation1 Vitamin A
Fatigue Resistance1 Creatine
Immunity (aka Immune system)1 Vitamin E
Cell Adhesion Factors (aka sCAM-11 Vitamin E, Fish Oil
Interferon Gamma1 Vitamin E
Dysmenorrhea1 Vitamin E
Interleukin 41 Vitamin E
Rate of Gastric Emptying1 Ginger
Treatment of Myotonic Dystrophy1 Creatine
Fertility1 Inositol
Hydration1 Creatine
Treatment of Hepatic Encephalopathy1 AcetylCarnitine
Muscular Endurance1 Creatine
Bone Mineral Density (aka BMD)1 Creatine
Plasma Vitamin C1 Vitamin C
Thyroid-Stimulating Hormone1 Iodine
Photoprotection1 Fish Oil
Leptin1 Conjugated Linoleic Acid, Zinc, Fish Oil
Endothelial Function1 Fish Oil
VO2 Max1 Resveratrol, Rhodiola Rosea, Creatine, Ashwagandha, AcetylCarnitine, Vitamin C, Fish Oil
Muscle Protein Synthesis1 Whey Protein
Serum Magnesium1 Magnesium
Cognition (Omnivores)Neutral Creatine
Lung FunctionNeutral Creatine
Exercise Capacity in COPDNeutral Creatine
Kidney Function (aka Renal function)Neutral Creatine
Exercise Capacity (with Heart Conditions)Neutral Creatine
TriglyceridesNeutral Conjugated Linoleic Acid, Inositol, Vitamin E, AcetylCarnitine, Magnesium
Treatment of Amyotrophic lateral sclerosis (ALS)Neutral Creatine
Metabolic RateNeutral Conjugated Linoleic Acid
Total CholesterolNeutral Creatine, Vitamin E, AcetylCarnitine
Treatment of COPDNeutral Creatine
Colon cancer riskNeutral Vitamin E
Pre-Eclampsia RiskNeutral Fish Oil
Breast Cancer RiskNeutral Vitamin E
Risk of StrokeNeutral Vitamin E
Bleeding TimeNeutral Vitamin E
White Blood Cell CountNeutral Vitamin E
Red Blood Cell CountNeutral Vitamin E
Postpartum DepressionNeutral Fish Oil
AdiponectinNeutral Conjugated Linoleic Acid
DNA DamageNeutral Vitamin E
Fat OxidationNeutral AcetylCarnitine
IGF-1 (aka Insulin-like growth factor-1)Neutral Conjugated Linoleic Acid, Whey Protein, Inositol, Creatine, Zinc, Magnesium, Fish Oil
BruisingNeutral Vitamin K
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  • 2016-10-12 14:32:25: Copper was added.
  • 2016-10-12 14:32:25: Dose unit of Copper was set to 1.
  • 2016-10-12 14:32:25: Start date of Copper was set to 2016-10-12.
  • 2016-10-12 14:32:25: Vitamin B1 was added.
  • 2016-10-12 14:32:25: Dose unit of Vitamin B1 was set to 1.
  • 2016-10-12 14:32:25: Start date of Vitamin B1 was set to 2016-10-12.
  • 2016-10-12 14:32:25: Biotin was added.
  • 2016-10-12 14:32:25: Dose unit of Biotin was set to 1.
  • 2016-10-12 14:32:25: Start date of Biotin was set to 2016-10-12.
  • 2016-10-12 14:32:25: GABA was added.
  • 2016-10-12 14:32:25: Dose unit of GABA was set to 1.
  • 2016-10-12 14:32:25: Start date of GABA was set to 2016-10-12.
  • 2016-10-12 14:32:25: Beta-Carotene was added.
  • 2016-10-12 14:32:25: Dose unit of Beta-Carotene was set to 1.
  • 2016-10-12 14:32:25: Start date of Beta-Carotene was set to 2016-10-12.
  • 2016-10-12 14:32:25: Evening Primrose Oil was added.
  • 2016-10-12 14:32:25: Dose unit of Evening Primrose Oil was set to 1.
  • 2016-10-12 14:32:25: Start date of Evening Primrose Oil was set to 2016-10-12.
  • 2016-10-12 14:32:25: Conjugated Linoleic Acid was added.
  • 2016-10-12 14:32:25: Dose unit of Conjugated Linoleic Acid was set to 1.
  • 2016-10-12 14:32:25: Start date of Conjugated Linoleic Acid was set to 2016-10-12.
  • 2016-10-12 14:32:25: Resveratrol was added.
  • 2016-10-12 14:32:25: Dose unit of Resveratrol was set to 1.
  • 2016-10-12 14:32:25: Start date of Resveratrol was set to 2016-10-12.
  • 2016-10-12 14:32:25: Ginger was added.
  • 2016-10-12 14:32:25: Dose unit of Ginger was set to 2.
  • 2016-10-12 14:32:25: Start date of Ginger was set to 2016-10-12.
  • 2016-10-12 14:32:24: Lions Mane was added.
  • 2016-10-12 14:32:24: Dose unit of Lions Mane was set to 1.
  • 2016-10-12 14:32:24: Start date of Lions Mane was set to 2016-10-12.
  • 2016-10-12 14:32:24: Pycnogenol was added.
  • 2016-10-12 14:32:24: Dose unit of Pycnogenol was set to 1.
  • 2016-10-12 14:32:24: Start date of Pycnogenol was set to 2016-10-12.
  • 2016-10-12 14:32:24: Iodine was added.
  • 2016-10-12 14:32:24: Dose unit of Iodine was set to 1.
  • 2016-10-12 14:32:24: Start date of Iodine was set to 2016-10-12.
  • 2016-10-12 14:32:24: Fish Oil was added.
  • 2016-10-12 14:32:24: Dose unit of Fish Oil was set to 1.
  • 2016-10-12 14:32:24: Start date of Fish Oil was set to 2016-10-12.
  • 2016-10-12 14:32:24: L-Theanine was added.
  • 2016-10-12 14:32:24: Dose unit of L-Theanine was set to 1.
  • 2016-10-12 14:32:24: Start date of L-Theanine was set to 2016-10-12.
  • 2016-10-12 14:32:24: Magnesium was added.
  • 2016-10-12 14:32:24: Dose unit of Magnesium was set to 1.
  • 2016-10-12 14:32:24: Start date of Magnesium was set to 2016-10-12.
  • 2016-10-12 14:32:24: Alpha GPC was added.
  • 2016-10-12 14:32:24: Dose unit of Alpha GPC was set to 1.
  • 2016-10-12 14:32:24: Start date of Alpha GPC was set to 2016-10-12.
  • 2016-10-12 14:32:24: Vitamin D was added.
  • 2016-10-12 14:32:24: Dose unit of Vitamin D was set to 1.
  • 2016-10-12 14:32:24: Start date of Vitamin D was set to 2016-10-12.
  • 2016-10-12 14:32:24: Noopept was added.
  • 2016-10-12 14:32:24: Dose unit of Noopept was set to 1.
  • 2016-10-12 14:32:24: Start date of Noopept was set to 2016-10-12.
  • 2016-10-12 14:32:24: Zinc was added.
  • 2016-10-12 14:32:24: Dose unit of Zinc was set to 1.
  • 2016-10-12 14:32:24: Start date of Zinc was set to 2016-10-12.
  • 2016-10-12 14:32:24: Vitamin C was added.
  • 2016-10-12 14:32:24: Dose unit of Vitamin C was set to 1.
  • 2016-10-12 14:32:24: Start date of Vitamin C was set to 2016-10-12.
  • 2016-10-12 14:32:24: AcetylCarnitine was added.
  • 2016-10-12 14:32:24: Dose unit of AcetylCarnitine was set to 1.
  • 2016-10-12 14:32:24: Start date of AcetylCarnitine was set to 2016-10-12.
  • 2016-10-12 14:32:24: Vitamin B12 was added.
  • 2016-10-12 14:32:24: Dose unit of Vitamin B12 was set to 1.
  • 2016-10-12 14:32:24: Start date of Vitamin B12 was set to 2016-10-12.
  • 2016-10-12 14:32:24: Vitamin E was added.
  • 2016-10-12 14:32:24: Dose unit of Vitamin E was set to 1.
  • 2016-10-12 14:32:24: Start date of Vitamin E was set to 2016-10-12.
  • 2016-10-12 14:32:24: Aniracetam was added.
  • 2016-10-12 14:32:24: Dose unit of Aniracetam was set to 1.
  • 2016-10-12 14:32:24: Start date of Aniracetam was set to 2016-10-12.
  • 2016-10-12 14:32:24: Bacopa monnieri was added.
  • 2016-10-12 14:32:24: Dose unit of Bacopa monnieri was set to 1.
  • 2016-10-12 14:32:24: Start date of Bacopa monnieri was set to 2016-10-12.
  • 2016-10-12 14:32:24: Piracetam was added.
  • 2016-10-12 14:32:24: Dose unit of Piracetam was set to 1.
  • 2016-10-12 14:32:24: Start date of Piracetam was set to 2016-10-12.
  • 2016-10-12 14:32:24: Ashwagandha was added.
  • 2016-10-12 14:32:24: Dose unit of Ashwagandha was set to 1.
  • 2016-10-12 14:32:24: Start date of Ashwagandha was set to 2016-10-12.
  • 2016-10-12 14:32:24: Creatine was added.
  • 2016-10-12 14:32:24: Dose unit of Creatine was set to 1.
  • 2016-10-12 14:32:24: Start date of Creatine was set to 2016-10-12.
  • 2016-10-12 14:32:24: Phenylpiracetam was added.
  • 2016-10-12 14:32:24: Dose unit of Phenylpiracetam was set to 1.
  • 2016-10-12 14:32:24: Start date of Phenylpiracetam was set to 2016-10-12.
  • 2016-10-12 14:32:24: Vitamin B6 was added.
  • 2016-10-12 14:32:24: Dose unit of Vitamin B6 was set to 1.
  • 2016-10-12 14:32:24: Start date of Vitamin B6 was set to 2016-10-12.
  • 2016-10-12 14:32:24: Folic Acid was added.
  • 2016-10-12 14:32:24: Dose unit of Folic Acid was set to 1.
  • 2016-10-12 14:32:24: Start date of Folic Acid was set to 2016-10-12.
  • 2016-10-12 14:32:24: Calcium was added.
  • 2016-10-12 14:32:24: Dose unit of Calcium was set to 1.
  • 2016-10-12 14:32:24: Start date of Calcium was set to 2016-10-12.
  • 2016-10-12 14:32:24: Sulbutiamine was added.
  • 2016-10-12 14:32:24: Dose unit of Sulbutiamine was set to 1.
  • 2016-10-12 14:32:24: Start date of Sulbutiamine was set to 2016-10-12.
  • 2016-10-12 14:32:24: Citicoline (CDP-Choline) was added.

Dosage Compound Form Frequency Dates Notes
0.00 g 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mcg 1X1,1,1,1,1,1,12016-10-12
0.00 g 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 g 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12
0.00 mg 1X1,1,1,1,1,1,12016-10-12

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Memory boost



Potential Interactions
Intake of large amounts of vitamin C can deplete the body of copper—an essential nutrient. People should be sure to maintain adequate copper intake at higher intakes of vitamin C. Copper is found in many multivitamin-mineral supplements.
Refrences
  • Sandstead HH. Copper bioavailability and requirements. Am J Clin Nutr 1982;35:809-14 [review].
  • Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553-6.
Long-term supplementation with vitamin B6 alone might reduce blood folic acid levels. Therefore, people with elevated blood homocysteine levels should supplement with both folic acid and vitamin B6.
Refrences
  • Mansoor MA, Kristensen O, Hervig T, et al. Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate. Scand J Clin Lab Invest 1999;59:139-46.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Vitamin B1 (thiamine) and magnesium work together in several different biochemical processes in the body. In patients who are deficient in both thiamine and magnesium, symptoms of thiamine deficiency may not respond to thiamine supplementation unless magnesium deficiency is also corrected. In addition, administration of large doses of thiamine can worsen magnesium deficiency. Magnesium supplementation should therefore be considered by people who are supplementing with thiamine.
Refrences
  • Gaby AR. Magnesium. In Gaby AR, Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 27
There is some evidence that magnesium may enhance calcium absorption.
Refrences
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.
Vitamin B6 increases the amount of magnesium that can enter cells. As a result, these two nutrients are often taken together.
Refrences
  • Abraham GE, Schwartz UD, Lubran MM. Effect of vitamin B-6 on plasma and red blood cell magnesium levels in premenopausal women. Ann Clin Lab Sci 1981;11:333-6.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Vitamin D’s most important role is maintaining blood levels of calcium. Therefore, many doctors recommend that those supplementing with calcium also supplement with 400–1,200 IU of vitamin D per day.
Refrences
  • Norman AW. Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 1990;51:290-300.
Supplementing with polyunsaturated fatty acids (which are present in evening primrose oil) increases vitamin E requirements. Therefore, people taking evening primrose oil may need additional vitamin E.
Refrences
  • Horwitt MK. Status of human requirements for vitamin E. Am J Clin Nutr 1974;27:1182-93.
Some evidence suggests that adding vitamin E to fish oil may prevent fish oil-induced increase in blood sugar levels.
Refrences
  • Luostarinen R, Wallin R, Wibell L, et al. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995; 15:953-68.
Vitamin E appears to increase intestinal absorption and tissue uptake of vitamin A. Because of this effect, some doctors have used the combination of vitamin E and vitamin A for various skin conditions that are usually treated with vitamin A alone. The addition of vitamin E improved outcomes, while allowing for lower (and safer) doses of vitamin A.
Refrences
  • Oaks L, Russell R, Jacob RA. Decreased serum vitamin A levels during vitamin E supplementation. Am J Clin Nutr 1978;31:716.
  • Ames SR. Factors affecting absorption, transport, and storage of vitamin A. The American journal of clinical nutrition. 1969 Jul;22(7):934-5
  • Gaby AR. Vitamin A. In Gaby AR. Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 11.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Zinc competes for absorption with calcium. A multimineral supplement will help prevent mineral imbalances.
Refrences
  • Argiratos V, Samman S. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Eur J Clin Nutr 1994;48:198-204.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Supplementation with zinc, iron, or the combination has been found to improve vitamin A status among children at high risk for deficiency of the three nutrients. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Muñoz EC, Rosado JL, Lopez P, et al. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nutr 2000;71:789-94.
In one study, administration of 1.9 g per day of calcium for 6 weeks to healthy individuals reduced the uptake of iodine by the thyroid gland. Further studies suggested that this effect of calcium was due to inhibition of gastrointestinal absorption of iodine. To be on the safe side, some doctors recommend that people taking calcium for long periods of time should also take a multimineral supplement that contains iodine.
Refrences
  • Boyle JA, Greig WR, Fulton S, Dalakos TG. Excess dietary calcium and human thyroid function. J Endocrinol 1966;34:531-532.

Supplementing with folic acid in amounts as little as 300 to 800 mcg per day may increase vitamin B12 requirements. Therefore, it would be prudent for people taking folic acid to supplement with vitamin B12.

Supplementation with vitamin B12, even in relatively small amounts, can increase folic acid requirements, For that reason, people taking vitamin B12 supplements should also consider taking folic acid.

In addition, supplementing with folic acid can mask the laboratory diagnosis of vitamin B12 deficiency. Failure to identify and treat vitamin B12 deficiency in a timely manner can lead to permanent neurological damage. The relatively small amount of vitamin B12 present in most supplements is not sufficient to prevent or correct vitamin B12 deficiency in people who have pernicious anemia (a condition caused by vitamin B12 malabsorption). For that reason, people should tell their doctor if they are taking folic acid supplements, so that the doctor will order alternative laboratory tests if vitamin B12 deficiency is suspected.


Refrences
  • Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5.
  • Steiner I,Melamed E. Folic acid and the nervous system. Neurology. 1983 Dec;33(12):1634
NAC may increase urinary zinc excretion. Therefore, supplemental zinc and copper should be added when supplementing with NAC for extended periods.
Refrences
  • Brumas V, Hacht B, Filella M, Berthon G. Can N-acetyl-L-cysteine affect zinc metabolism when used as a paracetamol antidote? Agents Actions 1992;36:278-88.
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
Refrences
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
Refrences
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.

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