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Focus

Cognitive Enhancement 459 Updated: 2016-05-17 rfhinds2
A Focus Complex Multivitamin from CVS that I found, will be adding more Nootropics to it.

146 Potential Effects from this Stack

Effect OnScaleContributors
Insulin Sensitivity3 Chromium, Zinc, Magnesium, Vitamin D, Vitamin E, Vitamin C
Cognition3 Phosphatidylserine, Choline Bitartrate, Zinc
Free Testosterone2 Phosphatidylserine, Glutamine, Chromium, Zinc, Magnesium, Vitamin D, Vitamin E
Blood Flow2 Vitamin E, Vitamin C
Memory2 Vinpocetine, Phosphatidylserine, Chromium, Vitamin E
Sleep Quality2 GABA, Magnesium
Serum Magnesium1 Magnesium
Lean Mass1 Glutamine, Chromium, Vitamin D
Interleukin 41 Vitamin E
Dysmenorrhea1 Vitamin E
Immunity (aka Immune system)1 Vitamin E
Interferon Gamma1 Vitamin E
Libido1 Chromium
Leptin1 Zinc
Skin dryness1 Vitamin A
Ammonia1 Glutamine
Plasma Vitamin C1 Vitamin C
Attention1 Phosphatidylserine
Anaerobic Exercise1 Phosphatidylserine, Chromium
Cortisol1 Phosphatidylserine, Glutamine, Magnesium, Vitamin E, Vitamin C
Sperm Quality1 Vitamin C
Skin pigmentation1 Vitamin A
Thyroid-Stimulating Hormone1 Iodine
Working Memory1 Phosphatidylserine
HomocysteineNeutral Vitamin E
DNA DamageNeutral Vitamin E
PainNeutral Vitamin D
Red Blood Cell CountNeutral Vitamin E
TriglyceridesNeutral Magnesium, Vitamin E
Cell Adhesion Factors (aka sCAM-1Neutral Vitamin E
Risk of StrokeNeutral Vitamin E
Aerobic ExerciseNeutral Vitamin C
Exercise-Induced Immune SuppressionNeutral Vitamin C
Protection from SmokingNeutral Vitamin C
VO2 MaxNeutral Vitamin C
Bleeding TimeNeutral Vitamin E
Breast Cancer RiskNeutral Vitamin E
Total CholesterolNeutral Vitamin E
White Blood Cell CountNeutral Vitamin E
Verbal FluencyNeutral Vitamin E
Colon cancer riskNeutral Vitamin E
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  • 2019-06-01 18:02:28: Archive was set to 1.
  • 2018-05-21 23:40:40: Archive was set to 1.
  • 2018-05-13 22:21:35: Archive was set to 1.
  • 2018-02-05 12:41:20: Archive was set to 1.
  • 2018-02-05 12:41:12: Archive was set to 1.
  • 2016-05-17 06:16:17: Bilberry Extract was added.
  • 2016-05-17 06:16:17: Dose unit of Bilberry Extract was set to 1.
  • 2016-05-17 06:16:17: Start date of Bilberry Extract was set to 2016-05-17.
  • 2016-05-17 06:16:17: Vinpocetine was added.
  • 2016-05-17 06:16:17: Dose unit of Vinpocetine was set to 1.
  • 2016-05-17 06:16:17: Start date of Vinpocetine was set to 2016-05-17.
  • 2016-05-17 06:16:17: Electrolyte Complex was added.
  • 2016-05-17 06:16:17: Dose unit of Electrolyte Complex was set to 1.
  • 2016-05-17 06:16:17: Start date of Electrolyte Complex was set to 2016-05-17.
  • 2016-05-17 06:16:17: Huperzine-A was added.
  • 2016-05-17 06:16:17: Dose unit of Huperzine-A was set to 1.
  • 2016-05-17 06:16:17: Start date of Huperzine-A was set to 2016-05-17.
  • 2016-05-17 06:16:17: Sodium Metavanadate was added.
  • 2016-05-17 06:16:17: Dose unit of Sodium Metavanadate was set to 1.
  • 2016-05-17 06:16:17: Start date of Sodium Metavanadate was set to 2016-05-17.
  • 2016-05-17 06:16:17: Vitamin B-2 (riboflavin) was added.
  • 2016-05-17 06:16:17: Dose quantity of Vitamin B-2 (riboflavin) was set to 1.7.
  • 2016-05-17 06:16:17: Dose unit of Vitamin B-2 (riboflavin) was set to 1.
  • 2016-05-17 06:16:17: Start date of Vitamin B-2 (riboflavin) was set to 2016-05-17.
  • 2016-05-17 06:16:17: Folic Acid was added.
  • 2016-05-17 06:16:17: Dose quantity of Folic Acid was set to 400.
  • 2016-05-17 06:16:17: Dose unit of Folic Acid was set to 3.
  • 2016-05-17 06:16:17: Start date of Folic Acid was set to 2016-05-17.
  • 2016-05-17 06:16:17: Vitamin B-6 was added.
  • 2016-05-17 06:16:17: Dose quantity of Vitamin B-6 was set to 15.
  • 2016-05-17 06:16:17: Dose unit of Vitamin B-6 was set to 1.
  • 2016-05-17 06:16:17: Start date of Vitamin B-6 was set to 2016-05-17.
  • 2016-05-17 06:16:17: Panthothenic Acid was added.
  • 2016-05-17 06:16:17: Dose quantity of Panthothenic Acid was set to 12.
  • 2016-05-17 06:16:17: Dose unit of Panthothenic Acid was set to 1.
  • 2016-05-17 06:16:17: Start date of Panthothenic Acid was set to 2016-05-17.
  • 2016-05-17 06:16:17: Vitamin B-12 was added.
  • 2016-05-17 06:16:17: Dose quantity of Vitamin B-12 was set to 20.
  • 2016-05-17 06:16:17: Dose unit of Vitamin B-12 was set to 3.
  • 2016-05-17 06:16:17: Start date of Vitamin B-12 was set to 2016-05-17.
  • 2016-05-17 06:16:17: Niacin was added.
  • 2016-05-17 06:16:17: Dose quantity of Niacin was set to 25.
  • 2016-05-17 06:16:17: Dose unit of Niacin was set to 1.
  • 2016-05-17 06:16:17: Start date of Niacin was set to 2016-05-17.
  • 2016-05-17 06:16:17: Biotin was added.
  • 2016-05-17 06:16:17: Dose quantity of Biotin was set to 300.
  • 2016-05-17 06:16:17: Dose unit of Biotin was set to 3.
  • 2016-05-17 06:16:17: Start date of Biotin was set to 2016-05-17.
  • 2016-05-17 06:16:17: Iodine was added.
  • 2016-05-17 06:16:17: Dose quantity of Iodine was set to 15.
  • 2016-05-17 06:16:17: Dose unit of Iodine was set to 3.
  • 2016-05-17 06:16:17: Start date of Iodine was set to 2016-05-17.
  • 2016-05-17 06:16:17: Magnesium was added.
  • 2016-05-17 06:16:17: Dose quantity of Magnesium was set to 100.
  • 2016-05-17 06:16:17: Dose unit of Magnesium was set to 1.
  • 2016-05-17 06:16:17: Start date of Magnesium was set to 2016-05-17.
  • 2016-05-17 06:16:17: Phosphorus was added.
  • 2016-05-17 06:16:17: Dose quantity of Phosphorus was set to 398.
  • 2016-05-17 06:16:17: Dose unit of Phosphorus was set to 1.
  • 2016-05-17 06:16:17: Start date of Phosphorus was set to 2016-05-17.
  • 2016-05-17 06:16:17: Iron was added.
  • 2016-05-17 06:16:17: Dose quantity of Iron was set to 5.
  • 2016-05-17 06:16:17: Dose unit of Iron was set to 1.
  • 2016-05-17 06:16:17: Start date of Iron was set to 2016-05-17.
  • 2016-05-17 06:16:17: Calcium was added.
  • 2016-05-17 06:16:17: Dose quantity of Calcium was set to 515.
  • 2016-05-17 06:16:17: Dose unit of Calcium was set to 1.
  • 2016-05-17 06:16:17: Start date of Calcium was set to 2016-05-17.
  • 2016-05-17 06:16:17: Zinc was added.
  • 2016-05-17 06:16:17: Dose quantity of Zinc was set to 10.
  • 2016-05-17 06:16:17: Dose unit of Zinc was set to 1.
  • 2016-05-17 06:16:17: Start date of Zinc was set to 2016-05-17.
  • 2016-05-17 06:16:17: Selenium was added.
  • 2016-05-17 06:16:17: Dose quantity of Selenium was set to 50.
  • 2016-05-17 06:16:17: Dose unit of Selenium was set to 3.
  • 2016-05-17 06:16:17: Start date of Selenium was set to 2016-05-17.
  • 2016-05-17 06:16:17: Copper was added.
  • 2016-05-17 06:16:17: Dose quantity of Copper was set to .4.
  • 2016-05-17 06:16:17: Dose unit of Copper was set to 1.
  • 2016-05-17 06:16:17: Start date of Copper was set to 2016-05-17.
  • 2016-05-17 06:16:17: Manganese was added.
  • 2016-05-17 06:16:17: Dose quantity of Manganese was set to 2.
  • 2016-05-17 06:16:17: Dose unit of Manganese was set to 1.
  • 2016-05-17 06:16:17: Start date of Manganese was set to 2016-05-17.
  • 2016-05-17 06:16:17: Chromium was added.
  • 2016-05-17 06:16:17: Dose quantity of Chromium was set to 100.
  • 2016-05-17 06:16:17: Dose unit of Chromium was set to 3.
  • 2016-05-17 06:16:17: Start date of Chromium was set to 2016-05-17.
  • 2016-05-17 06:16:17: Potassium was added.
  • 2016-05-17 06:16:17: Dose quantity of Potassium was set to 50.
  • 2016-05-17 06:16:17: Dose unit of Potassium was set to 1.
  • 2016-05-17 06:16:17: Start date of Potassium was set to 2016-05-17.
  • 2016-05-17 06:16:17: GABA was added.
  • 2016-05-17 06:16:17: Dose unit of GABA was set to 1.
  • 2016-05-17 06:16:17: Start date of GABA was set to 2016-05-17.
  • 2016-05-17 06:16:17: Inositol Bacopa Monnieri was added.
  • 2016-05-17 06:16:17: Dose unit of Inositol Bacopa Monnieri was set to 1.
  • 2016-05-17 06:16:17: Start date of Inositol Bacopa Monnieri was set to 2016-05-17.
  • 2016-05-17 06:16:17: L-Glutamine was added.
  • 2016-05-17 06:16:17: Dose unit of L-Glutamine was set to 1.

Dosage Compound Form Frequency Dates Notes
0 mgSodium Metavanadate 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
0 mgElectrolyte Complex 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
0 mgBilberry Extract 1X1,1,1,1,1,1,12016-05-17
0 mgDMAE Bitartrate 1X1,1,1,1,1,1,12016-05-17
0 mgBoron Citrate 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
0 mgDHA 1X1,1,1,1,1,1,12016-05-17
0 mgMolybdenum 1X1,1,1,1,1,1,12016-05-17
0 mgN-Acetyl-L-Tyrosine 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
0 mgInositol Bacopa Monnieri 1X1,1,1,1,1,1,12016-05-17
0.00 mg 1X1,1,1,1,1,1,12016-05-17
50 mg 1X1,1,1,1,1,1,12016-05-17
100 mcgChromium 1X1,1,1,1,1,1,12016-05-17
2 mgManganese 1X1,1,1,1,1,1,12016-05-17
0.4 mg 1X1,1,1,1,1,1,12016-05-17
50 mcg 1X1,1,1,1,1,1,12016-05-17
10 mg 1X1,1,1,1,1,1,12016-05-17
515 mg 1X1,1,1,1,1,1,12016-05-17
5 mg 1X1,1,1,1,1,1,12016-05-17
398 mg 1X1,1,1,1,1,1,12016-05-17
100 mg 1X1,1,1,1,1,1,12016-05-17
15 mcg 1X1,1,1,1,1,1,12016-05-17
300 mcg 1X1,1,1,1,1,1,12016-05-17
25 mgNiacin 1X1,1,1,1,1,1,12016-05-17
20 mcgVitamin B-12 1X1,1,1,1,1,1,12016-05-17
12 mgPanthothenic Acid 1X1,1,1,1,1,1,12016-05-17
15 mgVitamin B-6 1X1,1,1,1,1,1,12016-05-17
400 mcg 1X1,1,1,1,1,1,12016-05-17
1.7 mgVitamin B-2 (riboflavin) 1X1,1,1,1,1,1,12016-05-17
100 iu 1X1,1,1,1,1,1,12016-05-17
30 iu 1X1,1,1,1,1,1,12016-05-17
4000 iu 1X1,1,1,1,1,1,12016-05-17
3 mgVitamin B-1 (thiamin) 1X1,1,1,1,1,1,12016-05-17
250 mg 1X1,1,1,1,1,1,12016-05-17

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Focus



Potential Interactions
Intake of large amounts of vitamin C can deplete the body of copper—an essential nutrient. People should be sure to maintain adequate copper intake at higher intakes of vitamin C. Copper is found in many multivitamin-mineral supplements.
Refrences
  • Sandstead HH. Copper bioavailability and requirements. Am J Clin Nutr 1982;35:809-14 [review].
  • Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553-6.
Some, but not all studies have found that iron supplementation decreases copper absorption or copper nutritional status.
Refrences
  • Haschke F, Ziegler EE, Edwards BB, Fomon SJ. Effect of iron fortification of infant formula on trace mineral absorption. J Pediatr Gastroenterol Nutr 1986;5:768-73.
  • Albers J, Dawson EB, McGanity WJ. Affect of elevated pre-natal iron supplementation on serum copper, zinc, and selenium levels. Am J Clin Nutr 1986;43:673.
  • Yip R,Reeves JD,Lönnerdal B, et al. Does iron supplementation compromise zinc nutrition in healthy infants? The American journal of clinical nutrition. 1985 Oct;42(4):683-7
Calcium from food and supplements interferes with heme-iron absorption. Separating these supplements has been advised.
Refrences
  • Hallberg L, Brune M, Erlandsson M, et al. Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans. Am J Clin Nutr 1991;53:112-9.
  • Hallberg L, Rossander-Hulthén L, Brune M, Gleerup A. Inhibition of haem-iron absorption in man by calcium. Br J Nutr 1992;69:533-40.
There is some evidence that magnesium may enhance calcium absorption.
Refrences
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.
One study has shown that taking calcium can interfere with the absorption of phosphorus, which, like calcium, is important for bone health. Although most western diets contain ample or even excessive amounts of phosphorus, older people who supplement with large amounts of calcium may be at risk of developing phosphorus deficiency. For this reason, the authors of this study recommend that, for elderly people, at least some of the supplemental calcium be taken in the form of tricalcium phosphate or some other phosphorus-containing preparation.
Refrences
  • Heaney RP, Nordin BEC. Calcium effects on phosphorus absorption: implications for the prevention and co-therapy of osteoporosis.J Am Coll Nutr 2002;21:239-44.
Taking vitamin A with iron helps treat iron deficiency, since vitamin A improves the absorption and/or utilization of iron. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Suharno D, West CE, Muhilal, et al. Supplementation with vitamin A and iron for nutritional anemia in pregnant women in West Java, Indonesia. Lancet 1993;342:1325-8.
  • Semba RD, Muhilal, West KP Jr, et al. Impact of vitamin A supplementation on hematological indicators of iron metabolism and protein status in children. Nutr Res 1992;12:469-78.
Although vitamin C increases iron absorption, the effect is relatively minor.
Refrences
  • Hunt JR, Gallagher SK, Johnson LK. Effect of ascorbic acid on apparent iron absorption by women with low iron stores. Am J Clin Nutr 1994;59:1381-5.
  • Hallberg L, Brune M, Rossander L. The role of vitamin C in iron absorption. Int J Vitam Nutr Res Suppl 1989;30:103-8.
  • Lynch SR, Cook JD. Interaction of vitamin C and iron. Ann N Y Acad Sci 1980;355:32-44.
  • Hallberg L, Brune M, Rossander L. Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbic-acid-rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum Nutr Appl Nutr 1986;40:97-113.
Vitamin D promotes intestinal absorption of phosphorus.
Refrences
  • Wasserman RH. Intestinal absorption of calcium and phosphorus. Federation proceedings. 1981 Jan;40(1):68-72
Vitamin D’s most important role is maintaining blood levels of calcium. Therefore, many doctors recommend that those supplementing with calcium also supplement with 400–1,200 IU of vitamin D per day.
Refrences
  • Norman AW. Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 1990;51:290-300.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Vitamin E appears to increase intestinal absorption and tissue uptake of vitamin A. Because of this effect, some doctors have used the combination of vitamin E and vitamin A for various skin conditions that are usually treated with vitamin A alone. The addition of vitamin E improved outcomes, while allowing for lower (and safer) doses of vitamin A.
Refrences
  • Oaks L, Russell R, Jacob RA. Decreased serum vitamin A levels during vitamin E supplementation. Am J Clin Nutr 1978;31:716.
  • Ames SR. Factors affecting absorption, transport, and storage of vitamin A. The American journal of clinical nutrition. 1969 Jul;22(7):934-5
  • Gaby AR. Vitamin A. In Gaby AR. Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 11.
Zinc competes for absorption with iron.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Crofton RW, Gvozdanovic D, Gvozdanovic S, et al. Inorganic zinc and the intestinal absorption of ferrous iron. Am J Clin Nutr 1989;50:141-4.
Zinc competes for absorption with calcium. A multimineral supplement will help prevent mineral imbalances.
Refrences
  • Argiratos V, Samman S. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Eur J Clin Nutr 1994;48:198-204.
High phosphorus intake may impair absorption of iron, copper, and zinc.
Refrences
  • Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371-9.
Supplementation with zinc, iron, or the combination has been found to improve vitamin A status among children at high risk for deficiency of the three nutrients. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Muñoz EC, Rosado JL, Lopez P, et al. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nutr 2000;71:789-94.
In one study, administration of 1.9 g per day of calcium for 6 weeks to healthy individuals reduced the uptake of iodine by the thyroid gland. Further studies suggested that this effect of calcium was due to inhibition of gastrointestinal absorption of iodine. To be on the safe side, some doctors recommend that people taking calcium for long periods of time should also take a multimineral supplement that contains iodine.
Refrences
  • Boyle JA, Greig WR, Fulton S, Dalakos TG. Excess dietary calcium and human thyroid function. J Endocrinol 1966;34:531-532.
High phosphorus intake may impair absorption of iron, copper, and zinc.
Refrences
  • Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371-9.
High phosphorus intake may impair absorption of iron, copper, and zinc.
Refrences
  • Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371-9.
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
Refrences
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
Refrences
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.

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