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Melatonin vs Citrulline

Melatonin vs Citrulline Comparison, Similarities & Differences


Read full Melatonin Review


Read our Melatonin Review

Melatonin is a hormone produced naturally and is taken to help treat insomnia and to improve sleep quality. It is tied to your circadian rhythm and can put it back in balance making you easier to fall and stay asleep. Moreover, Melatonin is known as a powerful anti-oxidant, protecting both lipids and proteins against free radicals that may cause damage. With thus, it promotes overall brain health condition. It is generally dosed at 1 to 3mg.

Citrulline is one of the three dietary amino acids in the urea cycle, alongside L-arginine and L-Ornithine. In the kidneys, Citrulline is turned into L-arginine and serves to be a more effective method in increasing L-arginine levels rather than L-arginine supplementation. Citrulline has been a popular supplement to support sports performance as well as cardiovascular health. This is because Citrulline supplementation has been shown to reduce fatigue and improve endurance for both aerobic and anaerobic prolonged exercises. However, there is not enough evidence to support the clain that Citrulline could also improve power output during exercise. On the other hand, Citrulline has been found to alleviate erectile dysfunction caused by high blood pressure.


N-Acetyl-5-Methoxytryptamine, Melatonine, Melovine, Melatol, Melatonex, Circadin

L-Citrulline, Stimol Brand Name, Watermelon extract



No dosage data available

A suggested dose for Citrulline to support circulatory health or to alleviate erectile dysfunction would be 1,000 mg taken three times a day with meals. This means that the total daily dose would be 3, 000 mg. As for the purpose of enhancing sports performance, a dose of 6,000-8,000 mg of Citrulline

No dosage data available

Side Effects

Reported side effects related with Melatonin usage include daytime sleepiness, headaches, and dizziness.

There has been no repoorted side effects yet related with the use of Cutrulline.


Total Users

There are no users taking this supplement.

There are no users taking this supplement.


3.33/5 based on 3 user votes


Evidence-Based Effects

  • Alertness - Decreased
  • Blood Pressure - Decreased
  • Cortisol - Increased
  • Gastrin - Increased
  • Growth Hormone - Increased
  • Inflammation - Decreased
  • Insomnia - Decreased
  • Insulin Sensitivity - Increased
  • Leptin - Increased
  • Memory - Increased
  • Muscle Damage - Decreased
  • Noradrenaline (aka norepinephrine) - Decreased
  • Plasma Melatonin - Increased
  • Sleep Quality - Increased
  • Stomach Ulcers - Decreased
  • Symptoms of Tinnitus - Decreased
  • Cancer Mortality - Decreased
  • Symptoms of Jet Lag - Decreased

  • Blood Pressure - Decreased
  • Fatigue - Decreased
  • Growth Hormone - Increased


No data available

Medical Conditions

No data available

Medical Symptoms

No data available


No data available

Commonly Paired With

No data available

Price & Brand

Editors RecommendationCertified Pick:

Buy Melatonin Supplement
Cost: $6.99
Buy Melatonin

Editors RecommendationCertified Pick:

Buy Citrulline Supplement
Cost: $12.99
Buy Citrulline

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