Modafinil, a drug under the class of wakefulness promoting agents that is mainly used to treat narcolepsy ( a condition that causes excessive daytime sleepiness), other sleep disorders and shift work sleep disorder seems to have an impressive nootropic property via increasing levels of stimulatory neurotransmitters in the brain. This drug is used to promote wakefulness and helps you stay awake during long hours of work especially for people whose work schedules interfere with the normal sleep routine. However, we should take note that Modafinil does not make up for the lack of sleep and is not used to treat tiredness on people who were deprived of sleep. Moreover, its wakefulness-promoting properties promotes increase in the individual's energy and attentiveness and has been shown to produce significant cognitive benefits due stimulation of dopamine receptors, including increased learning capacity, better memory and faster recall.
Sulbutiamine is one of the most motivating nootropics owing to its ability to affect Dopamine levels in the brain. However, this should only be taken only if needed and not every day since tolerance to this drug can quickly develop.
Phenylpiracetam is essentially Piracetam with a phenyl group attached to it. This new structure in turn, increases the drug's potency by allowing its molecules to pass the blood-brain barrier more easily. Although the exact mechanism of Phenylpiracetam is not fully understood, its boosting effects can be attributed to its close resemblance of phenylethylamine, an organic compound known for its stimulatory effects. The added structure of the phenyl group then increases the affinity of Norepinephrine and Dopamine- the neurotransmitters responsible for vigilant concentration, cognitive alertness and motor control. It also raises Noradrenaline levels in the brain thus enhancing physical performance as well.
Alpha-GPC is the most effective type of Choline which increases the production, synthesis, and secretion of acetylcholine, the brain chemical that is important for memory and learning functions. Also, instead of being a precursor to phosphatidylcholine (PC), GPC is actually a metabolite of PC which is important for the communication between neurons. A dose of 400mg is taken 2x daily.