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Rheumatoid Arthritis Stack

General Health 429 SupplementDoctor
Rheumatoid arthritis is a chronic inflammatory polyarthritis and although individual patients may vary, its course tends to be chronic progressive. This then, may result in significant functional limitation and physical disability. RA is also associated with decreased survival when compared with the general population. According to research or other evidence, the following self-care steps may be helpful.

99 Potential Effects from this Stack

Effect OnScaleContributors
Memory2 Ginger, Vitamin E, Fish Oil
Lipid Peroxidation1 Zinc, Vitamin E, Fish Oil
Leptin1 Zinc, Fish Oil
Immunity (aka Immune system)1 Vitamin E
Photoprotection1 Fish Oil
Blood Flow1 Vitamin E, Fish Oil
Endothelial Function1 Fish Oil
Cell Adhesion Factors (aka sCAM-11 Vitamin E, Fish Oil
IGF-1 (aka Insulin-like growth factor-1)1 Zinc, Fish Oil
Interleukin 41 Vitamin E
Insulin Sensitivity1 Zinc, Vitamin E, Fish Oil
Interferon Gamma1 Vitamin E
Rate of Gastric Emptying1 Ginger
Cognition1 Zinc
Dysmenorrhea1 Vitamin E
Infant Birth Weight1 Fish Oil
Free Testosterone1 Zinc, Vitamin E, Fish Oil
Apolipoprotein BNeutral Fish Oil
Serum T4Neutral Vitamin E
Bleeding TimeNeutral Vitamin E
Verbal FluencyNeutral Vitamin E
AttentionNeutral Fish Oil
Colon cancer riskNeutral Vitamin E
Breast Cancer RiskNeutral Vitamin E
Risk of StrokeNeutral Vitamin E
Lean MassNeutral Fish Oil
Pre-Eclampsia RiskNeutral Fish Oil
T Cell CountNeutral Fish Oil
VO2 MaxNeutral Fish Oil
B cell countNeutral Fish Oil
Postpartum DepressionNeutral Fish Oil
Natural Killer Cell Content (aka NK cellNeutral Fish Oil
FatigueNeutral Fish Oil
Insulin SecretionNeutral Fish Oil
Serum T3Neutral Vitamin E
Muscle Soreness (aka Delayed onset muscle sorenessNeutral Fish Oil
Fat MassNeutral Fish Oil
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Yucca, a traditional remedy, is a desert plant that contains soap-like components known as saponins. Yucca tea is often drunk for relief of rheumatoid arthritis symptoms.
0.00 ,,,,,,
Studies conducted in India with the herb picrorhiza show a benefit for people with rheumatoid arthritis.
0.00 ,,,,,,
D-phenylalanine has been used with mixed results to treat chronic pain, including pain caused by rheumatoid arthritis.
0.00 ,,,,,,
Nettle has been used historically as a treatment for arthritis. It is applied topically, with the intent of causing stings to relieve arthritis pain.
0 Meadowsweet ,,,,,,
Meadowsweet has been used historically for a wide variety of conditions, including treating rheumatic complaints of the joints and muscles.
0.00 ,,,,,,
Taking glucosamine hydrochloride improved pain in people with rheumatoid arthritis in one study.
0.00 ,,,,,,
Ginger is an Ayurvedic herb used to treat people with arthritis. Taking fresh or powdered ginger may reduce the symptoms of rheumatoid arthritis.
0.00 ,,,,,,
People with rheumatoid arthritis tend to be deficient in copper, which acts as an anti-inflammatory agent needed to activate an enzyme that protects joints from inflammation.
0.00 ,,,,,,
Chaparral has anti-inflammatory effects and has a long history of use in treating joints affected by rheumatoid arthritis.
0 Burdock ,,,,,,
Burdock root has been used historically both internally and externally to treat painful joints.
0.00 ,,,,,,
Bromelain has significant anti-inflammatory activity and may help reduce joint swelling and improve joint mobility.
0.00 ,,,,,,
Boron supplementation may be beneficial, particularly in treating people with juvenile rheumatoid arthritis.
0.00 ,,,,,,
When stomach acid is low, supplementing with betaine HCl can reduce food-allergy reactions and help some people with rheumatoid arthritis.
0.00 ,,,,,,
Deficient zinc levels have been reported in people with rheumatoid arthritis. Some trials have found that supplementing with zinc reduces rheumatoid arthritis symptoms.
400 mg ,,,,,,
400 mg of curcumin three times daily. Turmeric's active constituent, curcumin, is a potent anti-inflammatory compound that protects the body against free radical damage.
200 mcg ,,,,,,
200 mcg daily. People with rheumatoid arthritis have been found to have lower selenium levels than healthy people. Supplementing with selenium may reduce pain and joint inflammation.
2000 mg ,,,,,,
2,000 mg daily. People with rheumatoid arthritis may be partially deficient in pantothenic acid. In one trial, taking pantothenic acid resulted in less morning stiffness, disability, and pain.
1050 mg ,,,,,,
1,050 to 2,100 mg daily of freeze-dried powder or 210 mg daily of lipid extract. Supplementing with New Zealand green-lipped mussel may improve rheumatoid arthritis symptoms, including joint tenderness and morning stiffness.
540 mg ,,,,,,
540 to 1,100 mg daily of GLA. Evening primrose oil appears to be an effective treatment for people with rheumatoid arthritis. It contains gamma linolenic acid, which is converted in part to an anti-inflammatory substance.
0.00 ,,,,,,
When applied to the skin, DMSO has anti-inflammatory properties and alleviates pain, apparently by inhibiting the transmission of pain messages by nerves.
540 mg ,,,,,,
540 mg daily for 30 days. Cetyl myristoleate may help relieve rheumatoid arthritis symptoms by acting as a joint lubricant and anti-inflammatory agent.
0.03 ,,,,,,
Apply 0.025 to 0.075% capsaicin ointment four times per day over painful areas. A cream containing capsaicin, a substance found in cayenne pepper, may help relieve pain when rubbed onto arthritic joints.
400 mg ,,,,,,
400 to 800 mg of gum resin extract three times daily. Boswellia, an herb used in Ayurvedic medicine to treat arthritis, has reduced rheumatoid arthritis symptoms in most reports.
1200 iu ,,,,,,
1,200 to 1,800 IU daily. Vitamin E is an important antioxidant, protecting joints against oxidative damage. Supplementing with vitamin E can help ease symptoms, including pain.
3 g ,,,,,,
3 grams daily of EPA plus DHA. Fish oil has anti-inflammatory effect and may help reduce pain. Many trials have proven that omega-3 fatty acids in fish oil partially relieve symptoms of rheumatoid arthritis.
1.1 g ,,,,,,
1.1 to 2.8 grams of GLA daily. Oils containing the omega-6 fatty acid gamma linolenic acid, such as borage oil, have been reported to be effective in treating people with rheumatoid arthritis.

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Rheumatoid Arthritis Stack



Potential Interactions
Supplementing with polyunsaturated fatty acids (which are present in evening primrose oil) increases vitamin E requirements. Therefore, people taking evening primrose oil may need additional vitamin E.
Refrences
  • Horwitt MK. Status of human requirements for vitamin E. Am J Clin Nutr 1974;27:1182-93.
Some evidence suggests that adding vitamin E to fish oil may prevent fish oil-induced increase in blood sugar levels.
Refrences
  • Luostarinen R, Wallin R, Wibell L, et al. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995; 15:953-68.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.

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