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Osteoporosis Stack

General Health 582 SupplementDoctor
Osteoporosis, also called as "porous bone," is a progressive decrease in bone mieral density and deterioration of the microarchitecture of bone tissues. It particularly affects the trabecular bones, making them weak thus, making fractures very likely. In Osteoporosis, BMD or bone mineral density is 2.5 SDs or more below that of a Òyoung normalÓ adult (T score ² 2.5). Stand tall against osteoporosis. No matter what your age, it's never too late to stop bone loss now for better posture and fewer fractures down the road. According to research or other evidence, the following self-care steps may be helpful.

112 Potential Effects from this Stack

Effect OnScaleContributors
Insulin Sensitivity4 Zinc, Whey Protein, Fish Oil, Vitamin K, Red Clover Extract, Magnesium, Vitamin D
Free Testosterone2 Zinc, Fish Oil, Red Clover Extract, Magnesium, Vitamin D
Lean Mass2 Whey Protein, Fish Oil, Vitamin D
Sleep Quality2 Red Clover Extract, Magnesium
Memory2 Fish Oil, Black Cohosh, Red Clover Extract
Endothelial Function1 Fish Oil
Cell Adhesion Factors (aka sCAM-11 Fish Oil
Muscle Protein Synthesis1 Whey Protein
Infant Birth Weight1 Fish Oil
Leptin1 Zinc, Fish Oil
Cognition1 Zinc, Black Cohosh
Serum Magnesium1 Magnesium
IGF-1 (aka Insulin-like growth factor-1)1 Zinc, Whey Protein, Fish Oil, Red Clover Extract, Magnesium
Photoprotection1 Fish Oil
B cell countNeutral Fish Oil
Symptoms of AlzheimersNeutral Fish Oil
VO2 MaxNeutral Fish Oil
Postpartum DepressionNeutral Fish Oil
T Cell CountNeutral Fish Oil
Pre-Eclampsia RiskNeutral Fish Oil
EstrogenNeutral Red Clover Extract
IGF Binding ProteinNeutral Red Clover Extract
HDL-CNeutral Magnesium
TriglyceridesNeutral Magnesium
PainNeutral Vitamin D
Sex Hormone Binding Globulin (aka SHBG)Neutral Red Clover Extract
Luteinizing Hormone (aka LH)Neutral Red Clover Extract
Apolipoprotein ANeutral Red Clover Extract
Bone Mineral Density (aka BMD)Neutral Red Clover Extract
Natural Killer Cell Content (aka NK cellNeutral Fish Oil
Follicle-Stimulating Hormone (aka FSH)Neutral Red Clover Extract
BruisingNeutral Vitamin K
Muscle Soreness (aka Delayed onset muscle sorenessNeutral Fish Oil
Apolipoprotein BNeutral Fish Oil
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Supplementing with zinc appears to be helpful in both preventing and treating osteoporosis.
0.00 ,,,,,,
Some whey proteins may reduce bone loss. Milk basic protein (MBP) is a mixture of some of the proteins found in whey protein and has been shown to promote bone density
0 Vitamin B-Complex ,,,,,,
In one trial postmenopausal women who combined hormone replacement therapy with B vitamins and other nutrients and dietary changes increased their bone density by a remarkable 11%.
0.00 ,,,,,,
Silicon is required in trace amounts for normal bone formation, and supplementation with silicon has increased bone mineral density in a small group of people with osteoporosis.
0 Manganese ,,,,,,
A combination of minerals including manganese was reported to halt bone loss in one study. Some doctors recommend manganese to people concerned with bone mass maintenance.
0.00 ,,,,,,
Horsetail is a rich source of silicon, and preliminary research suggests that this trace mineral may help maintain bone mass.
0.00 ,,,,,,
Supplementing with fish oil may improve calcium absorption and promote bone formation.
0.00 ,,,,,,
Supplementing with boron has been reported to reduce urinary loss of calcium and magnesium. However, those already supplementing with magnesium appear to achieve no additional calcium-sparing benefit when boron is added. Therefore, people with osteoporosis should supplement with magnesium or boron, not both.
0.00 ,,,,,,
Black cohosh has been shown to improve bone mineral density in animals fed a low-calcium diet.
1000 mcg ,,,,,,
1,000 mcg daily. Vitamin K is needed for bone formation, and supplementing with it may be a way to maintain bone mass.
26 mg ,,,,,,
Take an extract supplying 26 mg of biochanin A, 16 mg of formononetin, 1 mg of genistein, and 0.5 mg of daidzein per day. Studies show, supplementing with isoflavones from red clover reduced the amount of bone loss from the spine by 45%, compared with a placebo.
0.00 ,,,,,,
Preliminary evidence suggests that progesterone might reduce osteoporosis risk by promoting bone density.
250 mg ,,,,,,
Adults: 250 mg up to 750 mg daily; for girls: 150 mg daily. Supplementing with magnesium has been shown to stop bone loss or increased bone mass in people with osteoporosis.
600 mg ,,,,,,
600 mg daily along with 1,000 mg calcium daily. Ipriflavone promotes the incorporation of calcium into bone and inhibits bone breakdown, thus preventing and reversing osteoporosis.
5 mg ,,,,,,
Take under medical supervision: 5 to 50 mg per day. DHEA may be helpful in preventing osteoporosis. In one trial, bone mineral density increased among healthy elderly women and men who were given DHEA.
2 mg ,,,,,,
2 to 3 mg daily. Copper is needed for normal bone synthesis, and one trial reported that copper reduced bone loss.
400 ,,,,,,
400 to 800 IU daily depending on age, sun exposure, and dietary sources. Vitamin D increases calcium absorption and helps make bones stronger. Vitamin D supplementation has reduced bone loss in women who don’t get enough of the vitamin from food and slowed bone loss in people with osteoporosis and in postmenopausal women. It also works with calcium to prevent some musculoskeletal causes of falls and subsequent fractures.
600 mg ,,,,,,
600 to 700 mg daily under medical supervision. Studies indicate that supplementing with strontium may help reduce bone pain, increase bone mineral density, and reduce the risk of some fractures.
800 mg ,,,,,,
800 to 1,500 mg daily depending on age and dietary calcium intake. Calcium supplements help prevent osteoporosis, especially for girls and premenopausal women. It is often recommended to help people already diagnosed with osteoporosis.

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Osteoporosis Stack

Potential Interactions
Boron may conserve the body’s use of calcium, magnesium, and vitamin D. In one study, the ability of boron to reduce urinary loss of calcium disappeared when subjects were also given magnesium. Therefore, boron may provide no special benefit in maintaining bone mass in the presence of adequate amounts of dietary magnesium.
  • Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.
There is some evidence that magnesium may enhance calcium absorption.
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.
Vitamin D’s most important role is maintaining blood levels of calcium. Therefore, many doctors recommend that those supplementing with calcium also supplement with 400–1,200 IU of vitamin D per day.
  • Norman AW. Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 1990;51:290-300.
Zinc competes for absorption with calcium. A multimineral supplement will help prevent mineral imbalances.
  • Argiratos V, Samman S. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Eur J Clin Nutr 1994;48:198-204.
In animal studies, large doses of strontium inhibited calcium absorption. Whether this interaction occurs in humans taking the amounts of strontium that are used for osteoporosis prevention is not known.
  • Omdahl JL,DeLuca HF. Strontium induced rickets: metabolic basis. Science (New York, N.Y.). 1971 Nov;174(4012):949-51
  • Omdahl JL,DeLuca HF. Rachitogenic activity of dietary strontium. I. Inhibition of intestinal calcium absorption and 1,25-dihydroxycholecalciferol synthesis. The Journal of biological chemistry. 1972 Sep;247(17):5520-6
  • Morohashi T,Sano T,Yamada S. Effects of strontium on calcium metabolism in rats. I. A distinction between the pharmacological and toxic doses. Japanese journal of pharmacology. 1994 Mar;64(3):155-62
  • Rousselet F,El Solh N,Maurat JP, et al. [Strontium and calcium metabolism. Interaction of strontium and vitamin D]. Comptes rendus des séances de la Société de biologie et de ses filiales. 1975 ;169(2):322-9
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.

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