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Osteoarthritis Stack

General Health 483 SupplementDoctor
Osteoarthritis is a condition characterized by focal areas of loss of articular cartilage within the synovial joints. This may be associaated with hypertrophy of the bone and thickening of the joint capsule, which is thought as a reaction of the synovial joints to injury. The most commonly affected joint involve the weight-bearing joints like the knee, hip, foot and spine. The main risk factors of osteoarthritis are old age, family history,, obesity, and joint trauma. According to research or other evidence, the following self-care steps may be helpful.

92 Potential Effects from this Stack

Effect OnScaleContributors
Memory2 Fish Oil, Ginger, Vitamin E
Lipid Peroxidation2 Fish Oil, Vitamin E
Blood Flow2 Fish Oil, Pycnogenol, Vitamin E
Prostate Cancer Risk1 Vitamin E
Photoprotection1 Fish Oil
Interferon Gamma1 Vitamin E
Immunity (aka Immune system)1 Vitamin E
Dysmenorrhea1 Vitamin E
Endothelial Function1 Fish Oil
Attention1 Fish Oil, Pycnogenol
Infant Birth Weight1 Fish Oil
Interleukin 41 Vitamin E
Cell Adhesion Factors (aka sCAM-11 Fish Oil, Vitamin E
Rate of Gastric Emptying1 Ginger
Cognition1 Pycnogenol
LDL-CNeutral Vitamin E
HDL-CNeutral Vitamin E
Blood GlucoseNeutral Vitamin E
C-Reactive ProteinNeutral Vitamin E
Cognitive DeclineNeutral Vitamin E
DNA DamageNeutral Vitamin E
Fecal WeightNeutral Vitamin E
Total CholesterolNeutral Vitamin E
Colon cancer riskNeutral Vitamin E
Verbal FluencyNeutral Vitamin E
Breast Cancer RiskNeutral Vitamin E
Risk of StrokeNeutral Vitamin E
Bleeding TimeNeutral Vitamin E
Serum T4Neutral Vitamin E
Serum T3Neutral Vitamin E
EuphoricNeutral Vitamin E
B cell countNeutral Fish Oil
TriglyceridesNeutral Vitamin E
White Blood Cell CountNeutral Vitamin E
Red Blood Cell CountNeutral Vitamin E
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Yucca contains saponins, which appear to block the release of toxins from the intestines that inhibit normal cartilage formation. In doing so, yucca may reduce osteoarthritis symptoms.
80 mg ,,,,,,
80 mg anthocyanins, the equivalent of approximately 100 120 cherries, 16 24 ounces tart cherry juice blend, 1 ounce of liquid concentrate, or 400 mg of concentrate in tablets or capsules. In a preliminary trial, people with osteoarthritis who took tart cherry extract for three months reported reduced joint tenderness and less joint pain and disability.
0.00 ,,,,,,
Supplementing with D-phenylalanine (DPA) has been shown to reduce chronic pain due to osteoarthritis. DPA inhibits the enzyme that breaks down some of the body’s natural painkillers.
0 Meadowsweet ,,,,,,
Meadowsweet has been historically used to treat complaints of the joints and muscles. The herb contains salicylates, chemicals related to aspirin, that may account for its ability to relieve osteoarthritis pain.
0.00 ,,,,,,
Injection of hyaluronic acid compounds into osteoarthritic joints, primarily the knee, has been shown to improve symptoms.
0.00 ,,,,,,
Horsetail has anti-arthritis actions and is rich in silicon, a trace mineral that plays a role in making and maintaining connective tissue.
0.00 ,,,,,,
The omega-3 fatty acids present in fish oil, EPA and DHA, have anti-inflammatory effects and may relieve pain.
0.00 ,,,,,,
Boron affects calcium metabolism, and people with OA have been reported to have low bone stores of boron. Supplementing with boron may replenish stores and improve symptoms.
0.00 ,,,,,,
In a double-blind trial, supplementation with curcuminoids significantly improved pain and overall functioning in people with osteoarthritis of the knee.
100 mg ,,,,,,
100 to 150 mg per day. Double-blind research has shown that Pycnogenol may improve symptoms of osteoarthritis, including reducing pain and the use of pain-relieving medication and improving walking performance.
0 Olive Leaf ,,,,,,
In a double-blind trial, people with osteoarthritis of the knee had a significant improvement in their pain after taking olive leaf extract.
0.00 ,,,,,,
Apply stinging nettle under the direction of a qualified healthcare practitioner. Stinging nettle has historically been used for joint pain and has been shown to be safe and effective for relieving the pain of osteoarthritis.
300 mg ,,,,,,
300 mg per day. Studies show, people who took krill oil saw significant reduction in arthritis severity and used less pain-relief medication than those taking placebo.
500 mg ,,,,,,
500 mg of a concentrated extract (3.5% guggulsterones) three times per day. In one trial, supplementing with guggul significantly improved symptoms in people with osteoarthritis of the knee.
1050 mg ,,,,,,
1,050 to 2,100 mg daily of freeze-dried powder or 210 mg daily of lipid extract. New Zealand green-lipped mussel supplements have been shown in various studies to reduce joint tenderness and stiffness and improve pain, including knee pain in people with osteoarthritis.
25 ,,,,,,
Apply a gel containing 25% DMSO under the direction of a qualified healthcare practitioner. Topical DMSO appears to be anti-inflammatory and able to relieve pain associated with osteoarthritis, possibly by inhibiting the transmission of pain messages by nerves.
90 mg ,,,,,,
90 mg of bromelain and 48 mg of trypsin, with 100 mg of rutosid, taken in enteric-coated pills three times per day. Studies show, people with painful osteoarthritis of the knee who received an oral enzyme-flavonoid preparation saw more improvement in pain and joint function than those who took a nonsteroidal anti-inflammatory (NSAID).
540 mg ,,,,,,
540 mg per day by mouth for 30 days. Cetyl myristoleate appears to be effective as a joint lubricant and anti-inflammatory agent.
0.00 ,,,,,,
Taking collagen hydrolysate may help relieve pain associated with osteoarthritis of the hip and knee.
0 Vitamin B3 (Niacin) ,,,,,,
Supplemental niacinamide (a form of vitamin B3) has been reported to increase joint mobility, improve muscle strength, and decrease fatigue in people with osteoarthritis.
1200 mg ,,,,,,
1200 mg daily. SAMe has anti-inflammatory, pain-relieving, and tissue-healing properties that may help protect the health of joints and reduce osteoarthritis symptoms.
1500 mg ,,,,,,
1,500 mg daily. Glucosamine sulfate is necessary for joint cartilage synthesis and repair. It has been shown to significantly reduce osteoarthritis symptoms and appears to be virtually free of side effects.
510 mg ,,,,,,
510 mg daily of a concentrated herbal extract, taken in divided doses. Ginger has historically been used for arthritis and rheumatism. Studies have shown it to be effective at relieving pain and swelling in people with osteoarthritis.
800 mg ,,,,,,
800 to 1,200 mg a day. Many trials have shown that supplementing with chondroitin sulfate reduces pain, increases joint mobility, and promotes healing within the joints.
0.03 ,,,,,,
Apply 0.025 to 0.075% capsaicin ointment four times per day over painful joints. When rubbed over painful joints, cayenne extract creams containing 0.025 to 0.075% capsaicin may reduce the pain and tenderness of osteoarthritis.
1000 mg ,,,,,,
1,000 mg daily boswellia resin herbal extract or two capsules, three times per day of Aticulin-F (formula containing 100 mg boswellia, 450 mg ashwagandha, 50 mg turmeric, and 50 mg zinc). A combination of boswellia, ashwagandha, turmeric, and zinc effectively treated pain and stiffness in one study, without the stomach irritation that is a common side effect of NSAIDs.

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Osteoarthritis Stack



Potential Interactions
Some evidence suggests that adding vitamin E to fish oil may prevent fish oil-induced increase in blood sugar levels.
Refrences
  • Luostarinen R, Wallin R, Wibell L, et al. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995; 15:953-68.

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