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Nootropics

General Health Stack 140 Updated: 2017-12-02  
Lista p alla nootropics jag tar.

Health Notes & References


This stack has no notes or references yet.
  • 2017-12-02 01:25:55: Notes of AcetylCarnitine was changed from CILTEP, to CILTEP, 750mg. ; ACETYLCHOLINE Brain Food, 319mg.
  • 2017-12-02 01:25:55: Dose quantity of AcetylCarnitine was changed from 750.00 to 1069.
  • 2017-12-02 01:25:55: Dose status of AcetylCarnitine was cleared. Previous value was Under
  • 2017-12-02 01:23:57: Peony was added.
  • 2017-12-02 01:23:57: Notes of Peony was set to ACETYLCHOLINE Brain Food, White Peony Extract.
  • 2017-12-02 01:23:57: Dose quantity of Peony was set to 383.
  • 2017-12-02 01:23:57: Dose unit of Peony was set to 1.
  • 2017-12-02 01:23:57: Start date of Peony was set to 2017-12-02.
  • 2017-12-02 01:23:57: Effectiveness of Peony was set to Can't tell.
  • 2017-12-02 01:22:19: Notes of Vitamin B5 was changed from Alpha Men, 50mg(833% RDI), Pantotensyra. ; ACETYLCHOLINE Brain Food, Pantethine, 287mg to Alpha Men, 50mg(833% RDI), Pantotensyra. ; ACETYLCHOLINE Brain Food, 287mg, Pantethine,.
  • 2017-12-02 01:21:52: Notes of Vitamin B5 was changed from Alpha Men, 833% RDI, Pantotensyra to Alpha Men, 50mg(833% RDI), Pantotensyra. ; ACETYLCHOLINE Brain Food, Pantethine, 287mg.
  • 2017-12-02 01:21:52: Dose quantity of Vitamin B5 was changed from 50.00 to 337.
  • 2017-12-02 01:17:45: Notes of Vitamin B1 was changed from Alpha Men, 1145%, Tiamin to Alpha Men, 12,6mg(1145% RDI), Thiamine. ; ACETYLCHOLINE Brain Food, 64mg.
  • 2017-12-02 01:17:45: Dose quantity of Vitamin B1 was changed from 12.60 to 76.6.
  • 2017-12-02 01:10:37: Notes of Alpha GPC was set to ACETYLCHOLINE Brain Food,.
  • 2017-12-02 01:10:37: Dose quantity of Alpha GPC was changed from 0.00 to 192.
  • 2017-12-02 01:10:37: Dose status of Alpha GPC was cleared. Previous value was Empty
  • 2017-12-02 00:39:37: Notes of Alpha Lipoic Acid was changed from Alpha Men, to Alpha Men, 25,5mg ; ALPHA LIPOIC ACID, 500mg.
  • 2017-12-02 00:39:37: Dose quantity of Alpha Lipoic Acid was changed from 25.50 to 525.5.
  • 2017-12-02 00:18:37: Notes of Magnesium was changed from MagTech, Magnesium NET amount, 50% DV to MagTech, Magnesium NET amount 200mg(50% DV) ; SEROTONIN Brain Food, Magnesium glycinate, 50mg(13% DV).
  • 2017-12-01 23:43:43: Niacinamide was added.
  • 2017-12-01 23:43:43: Notes of Niacinamide was set to SEROTONIN Brain Food, Vitamin B3, 750% DV.
  • 2017-12-01 23:43:43: Dose quantity of Niacinamide was set to 150.
  • 2017-12-01 23:43:43: Dose unit of Niacinamide was set to 1.
  • 2017-12-01 23:43:43: Start date of Niacinamide was set to 2017-12-01.
  • 2017-12-01 23:43:43: Effectiveness of Niacinamide was set to Can't tell.
  • 2017-12-01 23:38:30: Zinc was added.
  • 2017-12-01 23:38:30: Notes of Zinc was set to Alpha Men, 15mg(150% RDI) ; SEROTONIN Brain Food, zinc glycinate, 20mg (133% DV).
  • 2017-12-01 23:38:30: Dose quantity of Zinc was set to 35.
  • 2017-12-01 23:38:30: Dose unit of Zinc was set to 1.
  • 2017-12-01 23:38:30: Dose status of Zinc was set to Recommended.
  • 2017-12-01 23:38:30: Start date of Zinc was set to 2017-12-01.
  • 2017-12-01 23:38:30: Effectiveness of Zinc was set to Can't tell.
  • 2017-12-01 23:33:29: Tryptophan was added.
  • 2017-12-01 23:33:29: Notes of Tryptophan was set to SEROTONIN Brain Food, L-Tryptophan, 1% DV.
  • 2017-12-01 23:33:29: Dose quantity of Tryptophan was set to 1250.
  • 2017-12-01 23:33:29: Dose unit of Tryptophan was set to 1.
  • 2017-12-01 23:33:29: Dose status of Tryptophan was set to Over.
  • 2017-12-01 23:33:29: Start date of Tryptophan was set to 2017-12-01.
  • 2017-12-01 23:33:29: Effectiveness of Tryptophan was set to Can't tell.
  • 2017-12-01 23:32:06: Rhodiola Rosea was added.
  • 2017-12-01 23:32:06: Notes of Rhodiola Rosea was set to SEROTONIN Brain Food, root extract, standardized to 3% total rosavin, min. 1% salidrosides.
  • 2017-12-01 23:32:06: Dose quantity of Rhodiola Rosea was set to 400.
  • 2017-12-01 23:32:06: Dose unit of Rhodiola Rosea was set to 1.
  • 2017-12-01 23:32:06: Dose status of Rhodiola Rosea was set to Recommended.
  • 2017-12-01 23:32:06: Start date of Rhodiola Rosea was set to 2017-12-01.
  • 2017-12-01 23:32:06: Effectiveness of Rhodiola Rosea was set to Can't tell.
  • 2017-12-01 23:28:46: Notes of Grape Seed Extract was changed from Alpha Men, 6,25mg. & GABA Brain Food, 33mg vitis vinfera, min 95% total polyphenols to Alpha Men, 6,25mg. ; GABA Brain Food, 33mg vitis vinfera, min 95% total polyphenols.
  • 2017-12-01 23:28:11: Notes of Grape Seed Extract was changed from Alpha Men, to Alpha Men, 6,25mg. & GABA Brain Food, 33mg vitis vinfera, min 95% total polyphenols.
  • 2017-12-01 23:28:11: Dose quantity of Grape Seed Extract was changed from 6.25 to 39.25.
  • 2017-12-01 23:24:13: Rosemary was added.
  • 2017-12-01 23:24:13: Notes of Rosemary was set to GABA Brain Food, leaf extract, standardized to 6% rosmarinic acid.
  • 2017-12-01 23:24:13: Dose unit of Rosemary was set to 1.
  • 2017-12-01 23:24:13: Start date of Rosemary was set to 2017-12-01.
  • 2017-12-01 23:24:13: Effectiveness of Rosemary was set to Can't tell.
  • 2017-12-01 23:22:17: Citrulline was added.
  • 2017-12-01 23:22:17: Notes of Citrulline was set to GABA Brain Food, L-Citrulline.
  • 2017-12-01 23:22:17: Dose quantity of Citrulline was set to 500.
  • 2017-12-01 23:22:17: Dose unit of Citrulline was set to 1.
  • 2017-12-01 23:22:17: Dose status of Citrulline was set to Under.
  • 2017-12-01 23:22:17: Start date of Citrulline was set to 2017-12-01.
  • 2017-12-01 23:22:17: Effectiveness of Citrulline was set to Can't tell.
  • 2017-12-01 23:21:15: Notes of GABA was set to GABA Brain Food,.
  • 2017-12-01 23:21:15: Dose quantity of GABA was changed from 0.00 to 633.
  • 2017-12-01 23:21:15: Dose status of GABA was cleared. Previous value was Empty
  • 2017-12-01 23:19:34: Magnesium Taurat was added.
  • 2017-12-01 23:19:34: Notes of Magnesium Taurat was set to MagTech, Magnesium.
  • 2017-12-01 23:19:34: Dose quantity of Magnesium Taurat was set to 630.
  • 2017-12-01 23:19:34: Dose unit of Magnesium Taurat was set to 1.
  • 2017-12-01 23:19:34: Start date of Magnesium Taurat was set to 2017-12-01.
  • 2017-12-01 23:19:34: Effectiveness of Magnesium Taurat was set to Can't tell.
  • 2017-12-01 23:18:37: Magnesium Glycinate was added.
  • 2017-12-01 23:18:37: Notes of Magnesium Glycinate was set to MagTech, Magnesium.
  • 2017-12-01 23:18:37: Dose quantity of Magnesium Glycinate was set to 690.
  • 2017-12-01 23:18:37: Dose unit of Magnesium Glycinate was set to 1.
  • 2017-12-01 23:18:37: Start date of Magnesium Glycinate was set to 2017-12-01.
  • 2017-12-01 23:18:37: Effectiveness of Magnesium Glycinate was set to Can't tell.
  • 2017-12-01 23:10:38: Notes of Magnesium was changed from MagTech, Magnesium NET amount to MagTech, Magnesium NET amount, 50% DV.
  • 2017-12-01 23:09:54: Notes of Magnesium was set to MagTech, Magnesium NET amount.
  • 2017-12-01 23:09:54: Dose quantity of Magnesium was changed from 0.00 to 200.
  • 2017-12-01 23:09:54: Dose status of Magnesium was cleared. Previous value was Empty
  • 2017-12-01 23:08:52: Notes of L-Threonate was set to MagTech, Magnesium.
  • 2017-12-01 23:08:52: Dose quantity of L-Threonate was changed from 0.00 to 1000.
  • 2017-12-01 23:08:52: Dose status of L-Threonate was cleared. Previous value was Empty
  • 2017-12-01 22:06:38: Pyridoxal phosphate was added.
  • 2017-12-01 22:06:38: Notes of Pyridoxal phosphate was set to CILTEP, Vitamin B6, pyridoxal-5-phosphate.
  • 2017-12-01 22:06:38: Dose quantity of Pyridoxal phosphate was set to 5.
  • 2017-12-01 22:06:38: Dose unit of Pyridoxal phosphate was set to 1.
  • 2017-12-01 22:06:38: Start date of Pyridoxal phosphate was set to 2017-12-01.
  • 2017-12-01 22:06:38: Effectiveness of Pyridoxal phosphate was set to Can't tell.
  • 2017-12-01 22:03:25: Notes of Vitamin B6 was changed from Alpha Men, 900% RDI to Alpha Men, 900% RDI, pyrodoxine.
  • 2017-12-01 21:59:42: Phenylalanine was added.
  • 2017-12-01 21:59:42: Notes of Phenylalanine was set to CILTEP, L-Phenylalanine.
  • 2017-12-01 21:59:42: Dose quantity of Phenylalanine was set to 500.
  • 2017-12-01 21:59:42: Dose unit of Phenylalanine was set to 1.
  • 2017-12-01 21:59:42: Dose status of Phenylalanine was set to Over.
  • 2017-12-01 21:59:42: Start date of Phenylalanine was set to 2017-12-01.
  • 2017-12-01 21:59:42: Effectiveness of Phenylalanine was set to Can't tell.
  • 2017-12-01 21:58:07: AcetylCarnitine was added.
  • 2017-12-01 21:58:07: Notes of AcetylCarnitine was set to CILTEP,.
Supplements 57 Supplements, 2 Drugs
Dosage Compound Class Frequency Dates Notes
383mg 1X2017-12-02
ACETYLCHOLINE Brain Food, White Peony Extract
150mg 1X2017-12-01
SEROTONIN Brain Food, Vitamin B3, 750% DV
35mg 1X2017-12-01
Alpha Men, 15mg(150% RDI) ; SEROTONIN Brain Food, zinc glycinate, 20mg (133% DV)
1250mg 1X2017-12-01
SEROTONIN Brain Food, L-Tryptophan, 1% DV
400mg 1X2017-12-01
SEROTONIN Brain Food, root extract, standardized to 3% total rosavin, min. 1% salidrosides
0.00mg 1X2017-12-01
GABA Brain Food, leaf extract, standardized to 6% rosmarinic acid
500mg 1X2017-12-01
GABA Brain Food, L-Citrulline
630mgMagnesium Taurat 1X2017-12-01
MagTech, Magnesium
690mgMagnesium Glycinate 1X2017-12-01
MagTech, Magnesium
5mg 1X2017-12-01
CILTEP, Vitamin B6, pyridoxal-5-phosphate
500mg 1X2017-12-01
CILTEP, L-Phenylalanine
1069mg 2017-12-01
CILTEP, 750mg. ; ACETYLCHOLINE Brain Food, 319mg
20mg 1X2017-12-01
CILTEP, root extract, Standardized to 20% forskolin 4mg
900mg 1X2017-12-01
CILTEP, 250% RDI, Cynara Scolymus, leaf, Standardized to 5% cynarins
76.6mg 2017-12-01
Alpha Men, 12,6mg(1145% RDI), Thiamine. ; ACETYLCHOLINE Brain Food, 64mg
25mg 2017-12-01
Alpha Men, 156% RDI, Niacin, NE
50mg 2017-12-01
Alpha Men, Koreanskt ginsengextrakt
20mg 2017-12-01
Alpha Men, Gingko biloba-extrakt
25mg 2017-12-01
Alpha Men, Bidrottninggele-extrakt
250mcg 2017-12-01
Alpha Men,
2.5mg 2017-12-01
Alpha Men,
2.5mg 2017-12-01
Alpha Men,
12.5mgPapain d 2017-12-01
Alpha Men,
12.5mg 2017-12-01
Alpha Men,
12.5mg 2017-12-01
Alpha Men,
12.5mg 2017-12-01
Alpha Men,
39.25mg 2017-12-01
Alpha Men, 6,25mg. ; GABA Brain Food, 33mg vitis vinfera, min 95% total polyphenols
12.5mg 1X2017-12-01
Alpha Men, Nsselextrakt
20mg 2017-12-01
Alpha Men, Kelp-pulver
25mg 2017-12-01
Alpha Men, Citrusbioflavonoider
525.5mg 2017-12-01
Alpha Men, 25,5mg ; ALPHA LIPOIC ACID, 500mg
25mcgMolybdenum 2017-12-01
Alpha Men, 50% RDI,
100mcgChromium 2017-12-01
Alpha Men, 250% RDI, Krom
80mcg 2017-12-01
Alpha Men, 145% RDI
1.5mgManganese 2017-12-01
Alpha Men, 80% RDI
0.2mg 2017-12-01
Alpha Men, 20% RDI
157.8mg 2017-12-01
Alpha Men, 20% RDI
354mg 2017-12-01
Alpha Men, 44% RDI,
337mg 2017-12-01
Alpha Men, 50mg(833% RDI), Pantotensyra. ; ACETYLCHOLINE Brain Food, 287mg, Pantethine,
150mcg 2017-12-01
Alpha Men, 300% RDI
126mcg 2017-12-01
Alpha Men, 5000% RDI
400mcg 2017-12-01
Alpha Men, 200% RDI
12.6mg 2017-12-01
Alpha Men, 900% RDI, pyrodoxine
12.6mgVitamin B2Riboflavin 2017-12-01
Alpha Men, 900%
80mg 2017-12-01
Alpha Men, 100% RDI
25mcg 2017-12-01
Alpha Men, 33% RDI
12mg 1X2017-12-01
Alpha Men, 55% RDI, a-TE
501mcg 2017-12-01
Alpha Men, 62% RDI (100%=808mcg), RE (retinol equivalents)
192mg 2017-11-30
ACETYLCHOLINE Brain Food,
5mcg 2017-11-30
Alpha Men, 100% RDI
0.00mg 1X2017-11-30
1000mg 2017-11-30
MagTech, Magnesium
200mg 2017-11-30
MagTech, Magnesium NET amount 200mg(50% DV) ; SEROTONIN Brain Food, Magnesium glycinate, 50mg(13% DV)
0.00mg 1X2017-11-30
633mg 2017-11-30
GABA Brain Food,
5g 1X2017-11-30
0.00mg 1X2017-11-30
0.00mg 1X2017-11-30
0.00mg 1X2017-11-30

Dosage Guidelines

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Nootropics



Potential Interactions

Biotin works with some other B vitamins, such as folic acid, pantothenic acid (vitamin B5), and vitamin B12. However, no solid evidence indicates that people supplementing with biotin also need to take these other vitamins. Symptoms of pantothenic acid or zinc deficiency have been reported to be lessened with biotin, though people with these deficiencies should supplement with the nutrients in which they are deficient.

There is one report of a 76-year-old woman who developed a life-threatening condition (eosinophilic pleuropericardial effusion) while taking 10 mg of biotin per day and 300 mg of pantothenic acid per day. However, it is not clear whether the vitamins caused the problem.


Refrences
  • Somer E. The Essential Guide to Vitamins and Minerals. New York: Harper, 1995, 70-2.
  • Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6.
Intake of large amounts of vitamin C can deplete the body of copper—an essential nutrient. People should be sure to maintain adequate copper intake at higher intakes of vitamin C. Copper is found in many multivitamin-mineral supplements.
Refrences
  • Sandstead HH. Copper bioavailability and requirements. Am J Clin Nutr 1982;35:809-14 [review].
  • Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553-6.
Flavonoids are often recommended along with vitamin C and may increase the effectiveness of vitamin C; citrus flavonoids, in particular, may improve the absorption of vitamin C.
Refrences
  • Clemetson CA, Andersen L. Plant polyphenols as antioxidants for ascorbic acid. Ann N Y Acad Sci 1966;136:341-76.
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Vinson JA, Bose P. Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract. Am J Clin Nutr 1988;48:601-4.
Long-term supplementation with vitamin B6 alone might reduce blood folic acid levels. Therefore, people with elevated blood homocysteine levels should supplement with both folic acid and vitamin B6.
Refrences
  • Mansoor MA, Kristensen O, Hervig T, et al. Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate. Scand J Clin Lab Invest 1999;59:139-46.
Vitamin B1 (thiamine) and magnesium work together in several different biochemical processes in the body. In patients who are deficient in both thiamine and magnesium, symptoms of thiamine deficiency may not respond to thiamine supplementation unless magnesium deficiency is also corrected. In addition, administration of large doses of thiamine can worsen magnesium deficiency. Magnesium supplementation should therefore be considered by people who are supplementing with thiamine.
Refrences
  • Gaby AR. Magnesium. In Gaby AR, Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 27
There is some evidence that magnesium may enhance calcium absorption.
Refrences
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.
One study has shown that taking calcium can interfere with the absorption of phosphorus, which, like calcium, is important for bone health. Although most western diets contain ample or even excessive amounts of phosphorus, older people who supplement with large amounts of calcium may be at risk of developing phosphorus deficiency. For this reason, the authors of this study recommend that, for elderly people, at least some of the supplemental calcium be taken in the form of tricalcium phosphate or some other phosphorus-containing preparation.
Refrences
  • Heaney RP, Nordin BEC. Calcium effects on phosphorus absorption: implications for the prevention and co-therapy of osteoporosis.J Am Coll Nutr 2002;21:239-44.
Vitamin B6 increases the amount of magnesium that can enter cells. As a result, these two nutrients are often taken together.
Refrences
  • Abraham GE, Schwartz UD, Lubran MM. Effect of vitamin B-6 on plasma and red blood cell magnesium levels in premenopausal women. Ann Clin Lab Sci 1981;11:333-6.
Vitamin D promotes intestinal absorption of phosphorus.
Refrences
  • Wasserman RH. Intestinal absorption of calcium and phosphorus. Federation proceedings. 1981 Jan;40(1):68-72
Vitamin D’s most important role is maintaining blood levels of calcium. Therefore, many doctors recommend that those supplementing with calcium also supplement with 400–1,200 IU of vitamin D per day.
Refrences
  • Norman AW. Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 1990;51:290-300.
Vitamin E appears to increase intestinal absorption and tissue uptake of vitamin A. Because of this effect, some doctors have used the combination of vitamin E and vitamin A for various skin conditions that are usually treated with vitamin A alone. The addition of vitamin E improved outcomes, while allowing for lower (and safer) doses of vitamin A.
Refrences
  • Oaks L, Russell R, Jacob RA. Decreased serum vitamin A levels during vitamin E supplementation. Am J Clin Nutr 1978;31:716.
  • Ames SR. Factors affecting absorption, transport, and storage of vitamin A. The American journal of clinical nutrition. 1969 Jul;22(7):934-5
  • Gaby AR. Vitamin A. In Gaby AR. Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 11.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Some evidence suggests that adding vitamin E to fish oil may prevent fish oil-induced increase in blood sugar levels.
Refrences
  • Luostarinen R, Wallin R, Wibell L, et al. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995; 15:953-68.
High phosphorus intake may impair absorption of iron, copper, and zinc.
Refrences
  • Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371-9.
Zinc competes for absorption with calcium. A multimineral supplement will help prevent mineral imbalances.
Refrences
  • Argiratos V, Samman S. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Eur J Clin Nutr 1994;48:198-204.
Supplementation with zinc, iron, or the combination has been found to improve vitamin A status among children at high risk for deficiency of the three nutrients. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Muñoz EC, Rosado JL, Lopez P, et al. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nutr 2000;71:789-94.

Supplementing with folic acid in amounts as little as 300 to 800 mcg per day may increase vitamin B12 requirements. Therefore, it would be prudent for people taking folic acid to supplement with vitamin B12.

Supplementation with vitamin B12, even in relatively small amounts, can increase folic acid requirements, For that reason, people taking vitamin B12 supplements should also consider taking folic acid.

In addition, supplementing with folic acid can mask the laboratory diagnosis of vitamin B12 deficiency. Failure to identify and treat vitamin B12 deficiency in a timely manner can lead to permanent neurological damage. The relatively small amount of vitamin B12 present in most supplements is not sufficient to prevent or correct vitamin B12 deficiency in people who have pernicious anemia (a condition caused by vitamin B12 malabsorption). For that reason, people should tell their doctor if they are taking folic acid supplements, so that the doctor will order alternative laboratory tests if vitamin B12 deficiency is suspected.


Refrences
  • Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5.
  • Steiner I,Melamed E. Folic acid and the nervous system. Neurology. 1983 Dec;33(12):1634
High phosphorus intake may impair absorption of iron, copper, and zinc.
Refrences
  • Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371-9.
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
Refrences
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
Refrences
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.



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