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High Cholesterol Stack

General Health 458 SupplementDoctor
Having high levels of cholesterol may predispose you in developing fatty acids in your blood vessels. This in turn, makes it difficult for enough blood to flow through your arteries, giving your heart and body inadequate oxygen, and putting you at risk of having a heart attack. High cholesterol, or hypercholesterolenemia, may be inherited, but can also be a result of unhealthy lifestyle choices, thus making it preventable and treatable. Take control of your cholesterol to lower your heart disease risk. According to research or other evidence, the following self-care steps may be helpful.

231 Potential Effects from this Stack

Effect OnScaleContributors
Insulin Sensitivity3 Vitamin E, Magnesium, AcetylCarnitine, Creatine, Royal Jelly, Garlic, Berberine, Vitamin C, Psyllium, Fenugreek, Chromium
Blood Flow3 Vitamin E, Pycnogenol, Vitamin C
Libido2 Fenugreek, Chromium
Anaerobic Exercise2 AcetylCarnitine, Creatine, HMB, Chromium
Free Testosterone2 Vitamin E, Magnesium, AcetylCarnitine, Creatine, Royal Jelly, Astaxanthin, HMB, Fenugreek, Chromium
Sperm Quality2 AcetylCarnitine, Astaxanthin, Vitamin C
Cognition2 Pycnogenol, AcetylCarnitine
Lean Mass2 AcetylCarnitine, Creatine, HMB, Fenugreek, Chromium
Attention2 Pycnogenol, AcetylCarnitine, Creatine
Power Output1 AcetylCarnitine, Creatine, Astaxanthin, HMB, Chromium
Sleep Quality1 Magnesium
Interleukin 41 Vitamin E
Dysmenorrhea1 Vitamin E
VO2 Max1 AcetylCarnitine, Creatine, Vitamin C
Hydration1 Creatine
Muscular Endurance1 Creatine, Chromium
Treatment of Myotonic Dystrophy1 Creatine
Plasma Vitamin C1 Vitamin C
Growth Hormone1 Creatine, HMB
Fatigue Resistance1 Creatine
Interferon Gamma1 Vitamin E
Muscle Carnitine Content1 AcetylCarnitine
Bone Mineral Density (aka BMD)1 Creatine
Treatment of Hepatic Encephalopathy1 AcetylCarnitine
Serum Magnesium1 Magnesium
Euphoric1 Vitamin E, Creatine
Cortisol1 Vitamin E, Magnesium, Creatine, Garlic, Vitamin C, HMB, Fenugreek
Immunity (aka Immune system)1 Vitamin E
Treatment of Amyotrophic lateral sclerosis (ALS)Neutral Creatine
Lung FunctionNeutral Creatine
Fat OxidationNeutral AcetylCarnitine
Treatment of COPDNeutral Creatine
Aerobic ExerciseNeutral AcetylCarnitine, Creatine, Vitamin C
MemoryNeutral Vitamin E, Creatine, Chromium
LeptinNeutral Garlic, Fenugreek
Exercise Capacity in COPDNeutral Creatine
Cognition (Omnivores)Neutral Creatine
Cognitive DeclineNeutral Vitamin E
HDL-CNeutral Vitamin E, Magnesium, AcetylCarnitine, Berberine, Astaxanthin, Psyllium
Kidney Function (aka Renal function)Neutral Creatine
Cell Adhesion Factors (aka sCAM-1Neutral Vitamin E
Fecal WeightNeutral Vitamin E, Magnesium, Astaxanthin, Psyllium
Exercise Capacity (with Heart Conditions)Neutral Creatine
DNA DamageNeutral Vitamin E
Symptoms of Peripheral Vascular DiseaseNeutral Garlic
Verbal FluencyNeutral Vitamin E
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Wild yam has been reported to raise HDL ( good ) cholesterol in preliminary research.
0.00 ,,,,,,
In one trial, supplementing with vitamin E increased levels of protective HDL cholesterol.
0.00 ,,,,,,
A double-blind trial found that, in people with moderately elevated cholesterol levels, supplementing with selenium in the form of high-selenium yeast resulted in a small but statistically significant decrease in serum cholesterol.
0.00 ,,,,,,
Sea buckthorn contains flavonoids and essential fatty acids that may influence blood cholesterol according to animal and preliminary human research.
150 mg ,,,,,,
150 mg per day. Preliminary research suggests that Pycnogenol may lower LDL cholesterol and raise HDL cholesterol in people with normal cholesterol levels.
0 Policosanol ,,,,,,
Policosanol may affect cholesterol levels by inhibiting cholesterol production by the liver but most research has casted doubt on its effectiveness.
0.00 ,,,,,,
The mushroom maitake may lower fat levels in the blood and be useful in lowering cholesterol.
0.00 ,,,,,,
In a preliminary study, magnesium supplementation lowered total cholesterol and increased HDL ("good") cholesterol levels.
0.00 ,,,,,,
Some preliminary trials report that L-carnitine reduces serum cholesterol and raises HDL cholesterol.
0.00 ,,,,,,
Preliminary Chinese research has found that high doses of the herb fo-ti may lower cholesterol levels.
0.00 ,,,,,,
One trial found that supplementing with creatine significantly lowered serum total cholesterol and triglycerides in people with high cholesterol.
0.00 ,,,,,,
Chondroitin sulfate has lowered serum cholesterol levels in preliminary trials.
0.00 ,,,,,,
Chitosan is a fiber-like supplement that has been shown to lower cholesterol and raise HDL ( good ) cholesterol).
0.00 ,,,,,,
Saponins in alfalfa seeds may block cholesterol absorption and prevent the formation of atherosclerotic plaques.
200 mg ,,,,,,
200 mg daily. Tocotrienols may lower cholesterol levels. Tocotrienols inhibited cholesterol synthesis in test-tube studies, and two trials found that tocotrienols reduced cholesterol levels by 13 15%.
50 mg ,,,,,,
50 to 100 mg daily. Supplementing with royal jelly may lower cholesterol levels.
1 g ,,,,,,
1 to 3 grams krill oil daily. Studies show of people with high cholesterol or triglycerides, supplementing with krill oil loweredtotal cholesterol, LDL cholesterol, and triglycerides, and increased HDL-cholesterol.
25 mg ,,,,,,
25 mg guggulsterones three times per day. Guggul appears to be helpful in lowering cholesterol and raising HDL ( good ) cholesterol.
3 cups ,,,,,,
3 cups daily. Green tea has been shown to lower total cholesterol levels and improve people's cholesterol profile.
600 mgGarlic ,,,,,,
600 to 900 mg a day of a standardizedherbal extract. Taking garlic may help lower cholesterol and prevent hardening of the arteries.
500 mg ,,,,,,
500 mg three times per day after meals. Supplementing with a cranberry extract has been shown to help lower total and LDL ("bad") cholesterol in people with type 2 diabetes taking hypoglycemic medication.
3 mg ,,,,,,
3 to 4 mg daily. Copper deficiency has been linked to high blood cholesterol, supplementing with it may correct a deficiency and lower cholesterol.
4 g ,,,,,,
4 to 32 grams per day. Activated charcoal has the ability to attach (adsorb) cholesterol and bile acids present in the intestine, preventing their absorption.
800 mg ,,,,,,
800 to 1,000 mg daily. Some trials have shown that supplementing with calcium reduces cholesterol levels.
0.8 g ,,,,,,
0.8 to 3.2 grams daily. Beta-sitosterol blocks cholesterol absorption and has been shown in studies to reduce blood levels of cholesterol.
500 mg ,,,,,,
500 mg twice per day. Berberine, a compound found in certain herbs such as goldenseal, barberry, and Oregon grape, has been found to lower serum cholesterol levels.
4 mg ,,,,,,
4 to 12 mg daily. Astaxanthin has antioxidant and other properties that may help improve blood cholesterol regulation and protect against lipoprotein oxidation.
0.00 ,,,,,,
Artichoke has moderately lowered cholesterol and triglycerides in some trials.
1000 mg ,,,,,,
1,000 mg daily. Vitamin C appears to protect LDL cholesterol from damage, and in some trials, cholesterol levels have fallen when people supplement with vitamin C.
1500 mgVitamin B3 (Niacin) ,,,,,,
1,500 to 3,000 mg daily under a doctors supervision. High amounts (several grams per day) of niacin, a form of vitamin B3, have been shown to lower cholesterol.
25 gSoy ,,,,,,
25 grams soy protein per day. Soy supplementation has been shown to lower cholesterol. Soy contains isoflavones, which are believed to be soy's main cholesterol-lowering ingredients.
1.2 mg ,,,,,,
1.2 to 2.4 grams (5 to 10 mg of monacolins) daily in divided amounts. One of the ingredients in red yeast rice appears to block the production of cholesterol in the liver.
5 g ,,,,,,
5 to 10 grams per day with meals. Psyllium has been shown to be effective at lowering total and LDL ( bad ) cholesterol.
300 mg ,,,,,,
300 mg pantethine taken two to four times per day. Pantethine, a byproduct of vitamin B5 (pantothenic acid), may help reduce the amount of cholesterol made by the body.
3 gHMB ,,,,,,
3 grams daily. Supplementing with HMB, or beta hydroxy-beta-methylbutyrate, is an effective way to lower total and LDL cholesterol.
4 g ,,,,,,
4 to 13 grams daily. Glucomannan is a water-soluble dietary fiber that has been shown to significantly reduce total blood cholesterol, LDL cholesterol, and triglycerides, and to raise HDL cholesterol.
10 g ,,,,,,
10 to 30 grams three times per day with meals. Fenugreek seeds contain compounds that inhibit both cholesterol absorption in the intestines and cholesterol production by the liver.
200 mcgChromium ,,,,,,
200 to 500 mcg daily. Chromium supplementation has reduced total cholesterol and LDL cholesterol and increased HDL cholesterol in double-blind and other controlled trials.
2900 mg ,,,,,,
2,900 to 15,000 mg daily. Beta-glucan is a type of soluble fiber that has been shown to lower total and LDL ( bad ) cholesterol and raise HDL ( good ) cholesterol.

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High Cholesterol Stack



Potential Interactions
Intake of large amounts of vitamin C can deplete the body of copper—an essential nutrient. People should be sure to maintain adequate copper intake at higher intakes of vitamin C. Copper is found in many multivitamin-mineral supplements.
Refrences
  • Sandstead HH. Copper bioavailability and requirements. Am J Clin Nutr 1982;35:809-14 [review].
  • Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553-6.
There is some evidence that magnesium may enhance calcium absorption.
Refrences
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.

Ingesting plant sterols interferes with beta-carotene and vitamin E absorption, resulting in lower blood levels of these nutrients.


Refrences
  • Richelle M, Enslen M, Hager C, et al. Both free and esterified plant sterols reduce cholesterol absorption and the bioavailability of beta-carotene and alpha-tocopherol in normocholesterolemic humans. Am J Clin Nutr 2004;80:171-7.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
Refrences
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303

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