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Bipolar Disorder Stack

General Health 411 SupplementDoctor
Bipolar disorder, also known as manic-depressive psychosis, is an affective disorder characterized by the occurrence of alternating manic, hypomanic, or mixed episodes and with major depressive episodes. This disorder may be due to a genetic cause or from brain structure and functioning. Signs and symptoms may include mood and behavior changes including extreme irritability, an overly long period of feeling sad or hopeless, feeling tired or "slowed" down, and many others. According to research or other evidence, the following self-care steps may be helpful.

79 Potential Effects from this Stack

Effect OnScaleContributors
Memory2 Citicoline (CDP-Choline), Fish Oil
Photoprotection1 Fish Oil
Insulin Sensitivity1 Vitamin C, Inositol, Fish Oil
Cell Adhesion Factors (aka sCAM-11 Fish Oil
Sperm Quality1 Vitamin C
Endothelial Function1 Fish Oil
Plasma Vitamin C1 Vitamin C
Fertility1 Inositol
Cortisol1 Vitamin C, 5-HTP, Fish Oil
Blood Flow1 Vitamin C, Fish Oil
Infant Birth Weight1 Fish Oil
HDL-C1 Inositol
Cognition1 Citicoline (CDP-Choline)
Attention1 Citicoline (CDP-Choline), Fish Oil
Free TestosteroneNeutral Fish Oil
Apolipoprotein BNeutral Fish Oil
LeptinNeutral Fish Oil
Pre-Eclampsia RiskNeutral Fish Oil
T Cell CountNeutral Fish Oil
B cell countNeutral Fish Oil
Postpartum DepressionNeutral Fish Oil
Natural Killer Cell Content (aka NK cellNeutral Fish Oil
Lean MassNeutral Fish Oil
Aerobic ExerciseNeutral Vitamin C
Muscle Soreness (aka Delayed onset muscle sorenessNeutral Fish Oil
Insulin SecretionNeutral Fish Oil
Symptoms of AlzheimersNeutral Inositol, Fish Oil
Protection from SmokingNeutral Vitamin C
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Vitamin C helps the body reduce its load of vanadium, a mineral that adversely influences bipolar disorder. It has improved symptoms of depression and mania in some studies.
0.00 ,,,,,,
Vitamin B12 deficiency has been associated with both mania and depression. Studies show, these symptoms cleared after treatment with B12 injections.
0.00 ,,,,,,
SAMe is an amino acid that has an impact on serotonin levels, it has shown significant antidepressant effects in clinical trials.
0.00 ,,,,,,
In a preliminary trial, depression in patients with bipolar disorder significantly improved after NAC treatment.
0.00 ,,,,,,
Inositol may be useful for treating depression in people with bipolar disorder.
0.00 ,,,,,,
Folic acid deficiency is associated with both mania and depression. Getting enough folic acid helps the body manufacture serotonin and other neurotransmitters.
0.00 ,,,,,,
Small amounts of choline are present in many B-complex and multivitamin supplements.. Though controlled trials are still needed to understand the effects of choline in people with bipolar disorder, acetylcholine levels in the brain may affect mood disorders and supplemental choline can increase acetylcholine levels.
0.00 ,,,,,,
Supplementing with 5-HTP has had antidepressant effects in people with bipolar disorder; the effect was greater when combined with an antidepressant drug (doctors supervision recommended)
0.00 ,,,,,,
Supplementation with L-tryptophan has led to improvement in depression in many studies, though its effect on bipolar disorder needs more study.
3 mg ,,,,,,
Daily omega-3 fatty acids: 9.6 grams for adults, 1,290 to 4,300 mg for children. People with depression may have lower blood levels of omega-3s. Taking fish oil, in addition to prescribed medication, improved symptoms in one study.

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Bipolar Disorder Stack



Potential Interactions

Supplementing with folic acid in amounts as little as 300 to 800 mcg per day may increase vitamin B12 requirements. Therefore, it would be prudent for people taking folic acid to supplement with vitamin B12.

Supplementation with vitamin B12, even in relatively small amounts, can increase folic acid requirements, For that reason, people taking vitamin B12 supplements should also consider taking folic acid.

In addition, supplementing with folic acid can mask the laboratory diagnosis of vitamin B12 deficiency. Failure to identify and treat vitamin B12 deficiency in a timely manner can lead to permanent neurological damage. The relatively small amount of vitamin B12 present in most supplements is not sufficient to prevent or correct vitamin B12 deficiency in people who have pernicious anemia (a condition caused by vitamin B12 malabsorption). For that reason, people should tell their doctor if they are taking folic acid supplements, so that the doctor will order alternative laboratory tests if vitamin B12 deficiency is suspected.


Refrences
  • Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5.
  • Steiner I,Melamed E. Folic acid and the nervous system. Neurology. 1983 Dec;33(12):1634

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