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Alzheimer’s Disease Stack

General Health Stack 2,294  
Alzheimer disease is a progressive disease of the brain that causes impairment of memory and dementia manifested b confusion, visual- spatial disorientation, impairment of language function progressing from anomia to fluent aphasia, inability to calculate and detorioration of judgement. There are six pillars of brain healthy lifestyle and that includes regular exercise, healthy diet, mental stimulation, quality sleep, mental stimulation and active social life. According to research or other evidence, the following self-care steps may be helpful.

Health Notes & References

This stack has no notes or references yet.
  • 2018-05-13 22:21:32: Archive was set to 1.
  • 2018-02-05 12:41:16: Archive was set to 1.
  • 2018-02-05 12:41:08: Archive was set to 1.
Supplements 19 Supplements
Dosage Compound Class Frequency Dates Notes
Some researchers feel Alzheimer's disease may be related to vitamin B12 deficiency.
In case reports, three patients with Alzheimer's disease showed improvements in symptoms such as irritability, agitation, anxiety, and apathy after supplementing with turmeric.
There is some evidence that cow-derived PS (phosphatidylserine) has been shown to improve mental function and feelings of well-being in people with Alzheimer's disease, though most research has not found benefit.
10 mg per day. A small, preliminary trial showed that oral NADH improved mental function in people with Alzheimer's disease.
Some researchers feel Alzheimer's disease may be related to folic acid deficiency.
Fish oil may help slow the rate of cognitive decline in people with very mild impairment.
DMAE (2-dimethylaminoethanol) may increase levels of a brain neurotransmitter, which may foster positive behavior changes in people with dementia.
People with Alzheimer's disease may have low DHEA (dehydroepiandrosterone) levels, and supplementation may improve mental performance.
Animal studies have found the Ayurvedic herb bacopa has constituents that enhance several aspects of mental function and learning ability.
4.5 grams per day for 12 weeks. A preliminary trial suggests that taking Panax ginseng may significantly improve a measure of cognitive function in the short term, though long-term use has not been established.
2,000 IU daily. Antioxidant supplements such as vitamin E have been associated with lower risk of Alzheimer's disease and improved brain function in middle-aged and older adults.
3 grams daily. Supplementing with vitamin B1 might slow Alzheimer's disease progression in people whose vitamin B1 dependent enzymes have low activity.
60 drops daily of a 1:1 tincture. Sage appears to have an effect on acetylcholine, one of the chemical messengers (neurotransmitters) in the brain and supplementing with sage has resulted in a significant improvement in cognitive function.
Lesser periwinkle contains the alkaloid vincamine, which has shown some benefit to people with Alzheimer's disease.
In a double-blind trial, supplementation with melatonin significantly improved cognitive function and sleep quality, compared with a placebo, in patients with Alzheimer's disease.
60 drops per day of a 1:1 herbal tincture, standardized to contain at least 500 mcg per ml of citral. Supplementing with an herbal extract of lemon balm (Melissa officinalis) has been shown to improve cognitive function and reduce agitation in people with Alzheimers disease.
200 mcg of huperzine A twice per day. Huperzine A, a substance found in the Chinese medicinal herb huperzia (Huperzia serrata), has been shown to improve memory and mental and behavioral function in people with dementia, including Alzheimer's disease.
120 to 240 mg of a standardized herbal extract daily. Ginkgo biloba extract is an approved treatment for early-stage Alzheimer's disease in Europe. It is thought to improve memory and quality of life and slow early disease progression.
1 gram taken three times per day. Short-term studies have found that people with Alzheimer's disease who supplement with acetyl-L-carnitine experience improved memory, enhanced overall performance, and delayed disease progression.

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Alzheimer’s Disease Stack

Potential Interactions

Some evidence suggests that adding vitamin E to fish oil may prevent fish oil-induced increase in blood sugar levels.
  • Luostarinen R, Wallin R, Wibell L, et al. Vitamin E supplementation counteracts the fish oil-induced increase of blood glucose in humans. Nutr Res 1995; 15:953-68.

Supplementing with folic acid in amounts as little as 300 to 800 mcg per day may increase vitamin B12 requirements. Therefore, it would be prudent for people taking folic acid to supplement with vitamin B12.

Supplementation with vitamin B12, even in relatively small amounts, can increase folic acid requirements, For that reason, people taking vitamin B12 supplements should also consider taking folic acid.

In addition, supplementing with folic acid can mask the laboratory diagnosis of vitamin B12 deficiency. Failure to identify and treat vitamin B12 deficiency in a timely manner can lead to permanent neurological damage. The relatively small amount of vitamin B12 present in most supplements is not sufficient to prevent or correct vitamin B12 deficiency in people who have pernicious anemia (a condition caused by vitamin B12 malabsorption). For that reason, people should tell their doctor if they are taking folic acid supplements, so that the doctor will order alternative laboratory tests if vitamin B12 deficiency is suspected.

  • Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5.
  • Steiner I,Melamed E. Folic acid and the nervous system. Neurology. 1983 Dec;33(12):1634

Check-In Posts

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Potential Effects from Stack

Memory5 Phosphatidylserine, Fish Oil, Bacopa monnieri, Vitamin E, Melatonin, Ginkgo biloba
Lipid Peroxidation2 Fish Oil, Vitamin E
Sleep Quality2 Melatonin, Ginkgo biloba
Cognition2 Phosphatidylserine, Bacopa monnieri, Ginkgo biloba
Blood Flow2 Fish Oil, Vitamin E, Ginkgo biloba
Prostate Cancer Risk1 Vitamin E
Insulin Sensitivity1 Fish Oil, Vitamin E, Melatonin
Immunity (aka Immune system)1 Vitamin E
Photoprotection1 Fish Oil
Euphoric1 Vitamin E, Ginkgo biloba
Leptin1 Fish Oil, Melatonin
Dysmenorrhea1 Vitamin E
Plasma Melatonin1 Melatonin
Calmness1 Ginkgo biloba
Ocular Blood Flow1 Ginkgo biloba
Growth Hormone1 Melatonin
Gastrin1 Melatonin
Endothelial Function1 Fish Oil
Interleukin 41 Vitamin E
Interferon Gamma1 Vitamin E
Infant Birth Weight1 Fish Oil
Attention1 Phosphatidylserine, Fish Oil, Bacopa monnieri, Melatonin, Ginkgo biloba
Working Memory1 Phosphatidylserine, Ginkgo biloba
Cell Adhesion Factors (aka sCAM-11 Fish Oil, Vitamin E
Anaerobic Exercise1 Phosphatidylserine
Serum T3Neutral Vitamin E
Fecal WeightNeutral Vitamin E
Serum T4Neutral Vitamin E
Heart RateNeutral Phosphatidylserine, Fish Oil, Vitamin E, Melatonin, Ginkgo biloba
White Blood Cell CountNeutral Vitamin E
TriglyceridesNeutral Vitamin E
Total CholesterolNeutral Vitamin E
Verbal FluencyNeutral Vitamin E, Ginkgo biloba
HDL-CNeutral Vitamin E
LDL-CNeutral Vitamin E
Breast Cancer RiskNeutral Vitamin E
Intraocular Pressure (aka IOP)Neutral Ginkgo biloba
LibidoNeutral Ginkgo biloba
Stroke Recovery RateNeutral Ginkgo biloba
Neutral Vitamin B12, Turmeric, Phosphatidylserine, NADH, Folic Acid, Fish Oil, DMAE, DHEA, Bacopa monnieri, Asian Ginseng, Vitamin E, Vitamin B1, Sage, Periwinkle, Melatonin, Lemon Balm, Huperzine A, Ginkgo biloba
AdrenalineNeutral Melatonin
Bleeding TimeNeutral Vitamin E
Free TestosteroneNeutral Phosphatidylserine, Fish Oil, Vitamin E
DNA DamageNeutral Vitamin E
Risk of StrokeNeutral Vitamin E
Colon cancer riskNeutral Vitamin E
Red Blood Cell CountNeutral Vitamin E
Pre-Eclampsia RiskNeutral Fish Oil
T Cell CountNeutral Fish Oil
Apolipoprotein BNeutral Fish Oil
Postpartum DepressionNeutral Fish Oil
Natural Killer Cell Content (aka NK cellNeutral Fish Oil
Muscle Soreness (aka Delayed onset muscle sorenessNeutral Fish Oil
C-Reactive ProteinNeutral Vitamin E
Lean MassNeutral Fish Oil
VO2 MaxNeutral Fish Oil
Insulin SecretionNeutral Fish Oil
IGF-1 (aka Insulin-like growth factor-1)Neutral Fish Oil
B cell countNeutral Fish Oil
Fat MassNeutral Fish Oil
Blood GlucoseNeutral Vitamin E
Symptoms of Acute Mountain Sickness-1 Ginkgo biloba
Numerical Memory-1 Ginkgo biloba
Cortisol-1 Phosphatidylserine, Fish Oil, Vitamin E, Melatonin, Ginkgo biloba
Insomnia-1 Melatonin
Noradrenaline (aka norepinephrine)-1 Melatonin
Blood Pressure-1 Phosphatidylserine, Fish Oil, Bacopa monnieri, Vitamin E, Melatonin, Ginkgo biloba
Symptoms of Jet Lag-1 Melatonin
Cancer Mortality-1 Melatonin
Alertness-1 Melatonin
Symptoms of Tinnitus-1 Melatonin, Ginkgo biloba
Stomach Ulcers-1 Melatonin
Cardiovascular Disease Mortality-1 Vitamin E
Natural Killer Cell Activity-1 Fish Oil
TNF-Alpha (aka TNF-α-1 Fish Oil
Liver Enzymes-1 Vitamin E
Homocysteine-1 Vitamin B12, Fish Oil, Vitamin E
General Oxidation-1 Vitamin E
Symptoms of Systemic Lupus Erythematosus-1 Fish Oil
vLDL-C-1 Fish Oil
Platelet Aggregation-1 Fish Oil
Symptoms of Bipolar Disorder (aka Manic-depressive disorder)-1 Fish Oil
Fatigue-1 Phosphatidylserine, Fish Oil
Cognitive Decline-2 Phosphatidylserine, Vitamin E, Ginkgo biloba
Muscle Damage-2 Phosphatidylserine, Fish Oil, Vitamin E, Melatonin
Depression-2 Fish Oil, Bacopa monnieri, Ginkgo biloba
Symptoms of Alzheimers-2 Fish Oil, Vitamin E, Ginkgo biloba
Inflammation-2 Phosphatidylserine, Fish Oil, Melatonin
Stress-3 Phosphatidylserine, Fish Oil, Ginkgo biloba
Anxiety-3 Fish Oil, Bacopa monnieri, Melatonin, Ginkgo biloba



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