Some researchers feel Alzheimer's disease may be related to vitamin B12 deficiency.
In case reports, three patients with Alzheimer's disease showed improvements in symptoms such as irritability, agitation, anxiety, and apathy after supplementing with turmeric.
There is some evidence that cow-derived PS (phosphatidylserine) has been shown to improve mental function and feelings of well-being in people with Alzheimer's disease, though most research has not found benefit.
10 mg per day. A small, preliminary trial showed that oral NADH improved mental function in people with Alzheimer's disease.
Some researchers feel Alzheimer's disease may be related to folic acid deficiency.
Fish oil may help slow the rate of cognitive decline in people with very mild impairment.
DMAE (2-dimethylaminoethanol) may increase levels of a brain neurotransmitter, which may foster positive behavior changes in people with dementia.
People with Alzheimer's disease may have low DHEA (dehydroepiandrosterone) levels, and supplementation may improve mental performance.
Animal studies have found the Ayurvedic herb bacopa has constituents that enhance several aspects of mental function and learning ability.
4.5 grams per day for 12 weeks. A preliminary trial suggests that taking Panax ginseng may significantly improve a measure of cognitive function in the short term, though long-term use has not been established.
2,000 IU daily. Antioxidant supplements such as vitamin E have been associated with lower risk of Alzheimer's disease and improved brain function in middle-aged and older adults.
3 grams daily. Supplementing with vitamin B1 might slow Alzheimer's disease progression in people whose vitamin B1 dependent enzymes have low activity.
60 drops daily of a 1:1 tincture. Sage appears to have an effect on acetylcholine, one of the chemical messengers (neurotransmitters) in the brain and supplementing with sage has resulted in a significant improvement in cognitive function.
Lesser periwinkle contains the alkaloid vincamine, which has shown some benefit to people with Alzheimer's disease.
In a double-blind trial, supplementation with melatonin significantly improved cognitive function and sleep quality, compared with a placebo, in patients with Alzheimer's disease.
60 drops per day of a 1:1 herbal tincture, standardized to contain at least 500 mcg per ml of citral. Supplementing with an herbal extract of lemon balm (Melissa officinalis) has been shown to improve cognitive function and reduce agitation in people with Alzheimers disease.
200 mcg of huperzine A twice per day. Huperzine A, a substance found in the Chinese medicinal herb huperzia (Huperzia serrata), has been shown to improve memory and mental and behavioral function in people with dementia, including Alzheimer's disease.
120 to 240 mg of a standardized herbal extract daily. Ginkgo biloba extract is an approved treatment for early-stage Alzheimer's disease in Europe. It is thought to improve memory and quality of life and slow early disease progression.
1 gram taken three times per day. Short-term studies have found that people with Alzheimer's disease who supplement with acetyl-L-carnitine experience improved memory, enhanced overall performance, and delayed disease progression.