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Alcohol Withdrawal Stack

General Health 353 SupplementDoctor
Alcohol withdrawal refers to a potentially life-threatening condition that can occur in people who have been drinking heavily for a long period of time and then either stop or significantly reduce their alcohol consumption. Symptoms such as headaches, jitters, upset stomach, mild anxiety, and seizures, in worst cases, can begin as early as two hours after the last drink and may persist for weeks. According to research or other evidence, the following steps may be helpful.

106 Potential Effects from this Stack

Effect OnScaleContributors
Insulin Sensitivity3 Vitamin E, Vitamin D, Vitamin C, Magnesium, Zinc
Blood Flow2 Vitamin E, Vitamin C
Free Testosterone2 Vitamin E, Vitamin D, Magnesium, Glutamine, Zinc
Immunity (aka Immune system)1 Vitamin E
Plasma Vitamin C1 Vitamin C
Prostate Cancer Risk1 Vitamin E
Interleukin 41 Vitamin E
Dysmenorrhea1 Vitamin E
Interferon Gamma1 Vitamin E
Skin dryness1 Vitamin A
Lean Mass1 Vitamin D, Glutamine
Sperm Quality1 Vitamin C
Sleep Quality1 Magnesium
Cortisol1 Vitamin E, Vitamin C, Magnesium, Glutamine
Ammonia1 Glutamine
Cognition1 Zinc
Leptin1 Zinc
Skin pigmentation1 Vitamin A
Serum Magnesium1 Magnesium
Risk of StrokeNeutral Vitamin E
PneumoniaNeutral Zinc
Colon cancer riskNeutral Vitamin E
IGF-1 (aka Insulin-like growth factor-1)Neutral Magnesium, Zinc
VO2 MaxNeutral Vitamin C
Bleeding TimeNeutral Vitamin E
InflammationNeutral Vitamin D, Vitamin C, Glutamine
Exercise-Induced Immune SuppressionNeutral Vitamin C
Aerobic ExerciseNeutral Vitamin C
Power OutputNeutral Vitamin D, Glutamine
PainNeutral Vitamin D
Protection from SmokingNeutral Vitamin C
DepressionNeutral Vitamin C, Zinc
Breast Cancer RiskNeutral Vitamin E
Cognitive DeclineNeutral Vitamin E
Red Blood Cell CountNeutral Vitamin E
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Alcohol-related anxiety may be improved by a combination of vitamin E, vitamin B6, niacin, and vitamin C, though the high amounts of niacin and vitamin B6 used in the study need a doctor's supervision.
0.00 ,,,,,,
If deficient, supplementing with this vitamin may help prevent bone loss and muscle weakness.
0.00 ,,,,,,
Vitamin C appears to help the body rid itself of alcohol. Alcohol-related anxiety may also be improved by a combination of vitamin C, vitamin B6, niacin, and vitamin E, though the high amounts B vitamins studied need a doctor's supervision.
0 Vitamin B-Complex ,,,,,,
Research suggests it is possible that successful treatment of B-complex vitamin deficiencies may actually reduce alcohol cravings, because animals crave alcohol when fed a B-complex-deficient diet.
0.00 ,,,,,,
Alcohol-related anxiety may be improved by a combination of vitamin B6, vitamin C, niacin, and vitamin E, though the high amounts of niacin and vitamin B6 used in the study need a doctor's supervision.
0 Vitamin B3 (Niacin) ,,,,,,
Preliminary research has suggested that niacin may help wean some alcoholics away from alcohol. Niacinamide a safer form of the same vitamin might have similar actions.
0.00 ,,,,,,
Supplementing with vitamin B1 (thiamine) may prevent brain damage and nerve disorders in people with alcoholism, including those withdrawing from alcohol.
0.00 ,,,,,,
Because of potential liver damage, correcting the vitamin A deficiency common to alcoholics requires a doctor's supervision to monitor liver function.
0 Multivitamin ,,,,,,
Because of multiple nutrient deficiencies associated with alcoholism, most alcoholics who quit drinking should take a high-potency multivitamin for at least several months after the detox period.
0.00 ,,,,,,
Alcoholics are sometimes deficient in magnesium, and some researchers believe that symptoms of withdrawal may result in part from this deficiency.
0.00 ,,,,,,
Traditional Chinese medicine, animal research, and some preliminary studies have found extracts of this herb may help reduce alcohol cravings, though some studies have not shown benefit.
0.00 ,,,,,,
Animal and double-blind human research has shown that this amino acid reduces desire for alcohol and anxiety levels.
0.00 ,,,,,,
In a double-blind study of alcoholics in a detox program, supplementing with EPO led to greater improvement than did placebo in some parameters of liver function.
0.00 ,,,,,,
Though not a treatment for withdrawal, beta-carotene supplementation may be a safe way to correct vitamin A deficiencies common to alcoholics (requires a doctor's supervision to monitor liver function and avoid damage).
135 mg ,,,,,,
Take under medical supervision: 135 to 215 mg daily. Supplementing with zinc may correct the deficiency common in alcoholic liver cirrhosis and may correct the impaired taste function that people with cirrhosis often experience.

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Alcohol Withdrawal Stack



Potential Interactions
Vitamin B1 (thiamine) and magnesium work together in several different biochemical processes in the body. In patients who are deficient in both thiamine and magnesium, symptoms of thiamine deficiency may not respond to thiamine supplementation unless magnesium deficiency is also corrected. In addition, administration of large doses of thiamine can worsen magnesium deficiency. Magnesium supplementation should therefore be considered by people who are supplementing with thiamine.
Refrences
  • Gaby AR. Magnesium. In Gaby AR, Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 27
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Vitamin B6 increases the amount of magnesium that can enter cells. As a result, these two nutrients are often taken together.
Refrences
  • Abraham GE, Schwartz UD, Lubran MM. Effect of vitamin B-6 on plasma and red blood cell magnesium levels in premenopausal women. Ann Clin Lab Sci 1981;11:333-6.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
Refrences
  • Horrobin DF. The importance of gamma-linolenic acid and prostaglandin E1 in human nutrition and medicine. J Holistic Med 1981;3:118-39.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Supplementing with polyunsaturated fatty acids (which are present in evening primrose oil) increases vitamin E requirements. Therefore, people taking evening primrose oil may need additional vitamin E.
Refrences
  • Horwitt MK. Status of human requirements for vitamin E. Am J Clin Nutr 1974;27:1182-93.
Vitamin E appears to increase intestinal absorption and tissue uptake of vitamin A. Because of this effect, some doctors have used the combination of vitamin E and vitamin A for various skin conditions that are usually treated with vitamin A alone. The addition of vitamin E improved outcomes, while allowing for lower (and safer) doses of vitamin A.
Refrences
  • Oaks L, Russell R, Jacob RA. Decreased serum vitamin A levels during vitamin E supplementation. Am J Clin Nutr 1978;31:716.
  • Ames SR. Factors affecting absorption, transport, and storage of vitamin A. The American journal of clinical nutrition. 1969 Jul;22(7):934-5
  • Gaby AR. Vitamin A. In Gaby AR. Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 11.
Supplementation with zinc, iron, or the combination has been found to improve vitamin A status among children at high risk for deficiency of the three nutrients. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Muñoz EC, Rosado JL, Lopez P, et al. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nutr 2000;71:789-94.
Other nutrients are needed by the body, along with EPO, to make PGE1. Consequently, some experts suggest that magnesium, zinc, vitamin C, niacin, and vitamin B6 should be taken along with EPO.
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
Refrences
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.

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