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Age-Related Cognitive Decline Stack

General Health 556 SupplementDoctor
From the name itself, age-related cognitive decline refers to the normal cognitive ageing, which is non-pathologic, normative and usual. The dterioration of the biological framework that underlies the ability to think and reason begins as early as mid twenties and includes a drop in regional brain volume, impaired neurotransmitter receptor binding and signaling, atered concentrations of brain metabolites, and many more. These changes, as a whole, gives a variety of symptoms associated with aging. This includes decreased ability to maintain focus and problem solving capability. Moreover, these changes may often lead to more serious conditions including dementia, depression, or Alzheimer's disease. With a little help you can reduce the effects of ARCD. According to research or other evidence, the following self-care steps may be helpful.

178 Potential Effects from this Stack

Effect OnScaleContributors
Memory5 Vitamin E, Melatonin, Vinpocetine, Bacopa monnieri, Phosphatidylserine, Ginkgo biloba
Cognition4 Pycnogenol, Bacopa monnieri, Phosphatidylserine, Ginkgo biloba, AcetylCarnitine
Blood Flow4 Vitamin E, Vitamin C, Pycnogenol, Ginkgo biloba
Attention3 Melatonin, Pycnogenol, Bacopa monnieri, Phosphatidylserine, Ginkgo biloba, AcetylCarnitine
Insulin Sensitivity2 Vitamin E, Vitamin C, Melatonin, AcetylCarnitine
Sperm Quality2 Vitamin C, Astaxanthin, AcetylCarnitine
Sleep Quality2 Melatonin, Ginkgo biloba
Anaerobic Exercise2 Phosphatidylserine, AcetylCarnitine
Dysmenorrhea1 Vitamin E
Interleukin 41 Vitamin E
Ocular Blood Flow1 Ginkgo biloba
Muscle Carnitine Content1 AcetylCarnitine
Euphoric1 Vitamin E, Ginkgo biloba
Plasma Vitamin C1 Vitamin C
Interferon Gamma1 Vitamin E
Immunity (aka Immune system)1 Vitamin E
Plasma Melatonin1 Melatonin
Cortisol1 Vitamin E, Vitamin C, Melatonin, Phosphatidylserine, Ginkgo biloba
Working Memory1 Phosphatidylserine, Ginkgo biloba
Treatment of Hepatic Encephalopathy1 AcetylCarnitine
Calmness1 Ginkgo biloba
Leptin1 Melatonin
Gastrin1 Melatonin
Growth Hormone1 Melatonin
Lean Mass1 AcetylCarnitine
Aerobic ExerciseNeutral Vitamin C, AcetylCarnitine
DepressionNeutral Vitamin C, Bacopa monnieri, Ginkgo biloba
Bleeding TimeNeutral Vitamin E
Exercise-Induced Immune SuppressionNeutral Vitamin C
LibidoNeutral Ginkgo biloba
Intraocular Pressure (aka IOP)Neutral Ginkgo biloba
Stroke Recovery RateNeutral Ginkgo biloba
AdrenalineNeutral Melatonin
VO2 MaxNeutral Vitamin C, AcetylCarnitine
Protection from SmokingNeutral Vitamin C
Verbal FluencyNeutral Vitamin E, Ginkgo biloba
HomocysteineNeutral Vitamin E
LDL-CNeutral Vitamin E, Astaxanthin, AcetylCarnitine
Fat OxidationNeutral AcetylCarnitine
Red Blood Cell CountNeutral Vitamin E
HDL-CNeutral Vitamin E, Astaxanthin, AcetylCarnitine
Free TestosteroneNeutral Vitamin E, Astaxanthin, Phosphatidylserine, AcetylCarnitine
Cell Adhesion Factors (aka sCAM-1Neutral Vitamin E
DNA DamageNeutral Vitamin E
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Dosage Compound Form Frequency Dates Notes
0.00 ,,,,,,
Use of vitamin E, alone or with vitamin C, has been associated with better cognitive function and a reduced risk of certain forms of dementia (but not Alzheimer's disease).
0.00 ,,,,,,
Use of vitamin C, alone or with vitamin E, has been associated with better cognitive function and a reduced risk of certain forms of dementia (not including Alzheimer's disease).
0.00 ,,,,,,
In a preliminary trial of individuals with mild cognitive impairment and low blood levels of selenium, the improvement in measures of cognitive function was significantly greater in the group eating Brazil nuts than in the control group.
0.00 ,,,,,,
Cognitive function is linked to adequate sleep and normal sleep-wake cycles, which are partially regulated by the hormone melatonin. The long-term effects of melatonin are unknown, use under a doctor's supervision.
50 mg ,,,,,,
50 mg every other day. Studies show, long-term beta-carotene supplementation slowed the loss of cognitive function in middle-aged healthy males.
0.00 ,,,,,,
Some, though not all, research has found astaxanthin might protect the brain from age-related oxidative damage.
20 mg ,,,,,,
20 mg daily. There is evidence that supplementing with vitamin B6 (pyridoxine) may improve memory performance, especially in people who are deficient.
30 mg ,,,,,,
30 to 60 mg daily. Vinpocetine has been shown to improve dementia symptoms in patients with various brain diseases.
150 mg ,,,,,,
150 mg per day. A study of healthy senior people reported that supplementing daily with Pycnogenol improved some measures of memory after three months, compared with a group taking a placebo.
100 mcg ,,,,,,
100 to 150 mcg two to three times per day. Huperzine A, an extract from a Chinese medicinal herb, has been found to improve cognitive function in seniors with memory disorders.
0.00 ,,,,,,
Animal studies have found this Ayurvedic herb enhances several aspects of mental function and learning ability, and there is some preliminary research that it improves mental function in humans.
300 mg ,,,,,,
300 mg daily of bovine-derived supplement. Bovine-derived PS (phosphatidylserine) has been shown to improve memory, cognition, and mood in the elderly. To date, most evidence suggests that soy-derived PS is not effective for ARCD.
120 mg ,,,,,,
120 to 160 mg daily. Most, but not all, clinical trials have found this herb to be a safe and effective treatment for ARCD.
1500 mg ,,,,,,
1,500 mg daily. Several clinical trials suggest that this supplement delays onset of ARCD and improves overall cognitive function in the elderly

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Age-Related Cognitive Decline Stack

Potential Interactions
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303

Saved Therapies Added Time Frequency Notes


Saved Activities Added Time Frequency Notes


Saved Nutrition Added Time Frequency Notes


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