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What are the Best Racetams?

racetamsRacetams, the colloquial name for a group of structurally identical nootropic chemicals ending with … “racetams”. We regard them on our site as supplements but they indeed are drugs.

The invention of the Racetam family of drugs happened accidentally. As Racetams were not being formulated as mental enhancers but designed as a cure for motion sickness.  Unanticipated discoveries similar to this are widespread in pharmacology.

The most famous Racetam is called Piracetam, others include:  Aniracetam, Oxiracetam and Pramiracetam possess a 2-pyrrolidine nucleus comprised of nitrogen , oxygen and hydrogen.

Learning improvements, enhanced memory and focus, elevated mood and high energy levels are some of the effects of Racetams. Stimulation of cholinergic receptors of the neurotransmitter acetylcholine is the mainstay of mechanism of Racetams. These also boost glutamate uptake via stimulating AMPA and NMDA receptors.

List of Racetams

About 19 diverse Racetam supplements have been contrived ever since the invention of Piracetam – the first Racetam compound.

The whole list of Racetams include: Aniracetam, Coluracetam, Brivaracetam, Dimiracetam, Fasoracetam, Etiracetam; Imuracetam, Nebracetam, Levetiracetam, Nefiracetam, Oxiracetam, Nicoracetam, Phenylpiracetam, Piracetam, Phenotropil, Pramiracetam, Rolziracetam, Rolipram and Seletracetam.

Most of  these substances are employed for many different health and medicinal purposes but some are commonly employed for use in the form of Nootropics: Piracetam, Oxiracetam, Aniracetam and Pramiracetam.

These four are discussed below to let you learn about which Racetam may be best for you:

Piracetam

Piracetam (known also as Nootropil) is the most commonly used Racetam supplement. It also possesses the privilege of being known as the very first Nootropic ever invented. Piracetam imposes its action via the stimulation of Acetylcholine receptor system leading to the release of neurotransmitters in the brain. Taking piracetam long term will improve brain health and also poses many other benefits in the short term.

Piracetam is more devoid of side effects than a cup of coffee owing to it astonishingly low toxicity profile.

Effects: Piracetam boosted cognitive ability on many metrics immediately. Improved learning and higher memory retention were experienced because of upgraded neuroplasticity. You will readily start to experience higher sensory perception and enhanced awareness. Piracetam also aids in studying and focusing because it heightens motivation and energizes you strongly.

Dosage: About 1.2 to 4.8 grams for 4 times a day is recommended for Piracetam to have noticeable effects according to our users. You can buy 500 g of Piracetam in $39.99, thereby making it affordable compared to other Racetams.

How to Take: Piracetam can be taken in form of powder by making a solution in water and can be combined with any other Nootropics you may want to stack together. Considering stacking with: CDP Choline, Alpha GPC or with any other source of choline as recommended by a physician. Piracetam depletes choline, and that is why having an adequate quantity of choline as part of your diet will help increase neurotransmitter formation.

Centrophenoxine when stacked with Piracetam is known to boost or increase your recall speed – making your mind sharper, highly focused, rather more instantaneous and reflexive when it comes to fact-recall abilities. You can additionally see piracetam alternatives here.

Aniracetam

aniracetamAniracetam is a stronger and longer lasting cousin of Piracetam. It is fat soluble and takes a longer time to kick-in. This means you should take it with fish oil or another fatty food source and also realize that it may take longer for the effects to diminish. Aniracetam is a better stimulator of AMPA receptors than Piracetam.

Effects: Aniracetam improves focus along with concentration as it is an AMPA receptor agonist. Aniracetam emerges as one of the best Racetams as well as Nootropics prescribed for studying.

Aniracetam also boosts perception of sound and recognition of colors. It hastens the communication between two brain hemispheres, lessens social anxiety and increases creativity.

Aniracetam Dosage: About 600 to 3000 mg are recommended per day. Most people ought to take Aniracetam  every 4 hours or as required to make sure that the effects last throughout the day. You may get a headache using this Racetam lest you supplement it with choline.

How to Take Aniracetam: The optimal method to take Aniracetam powder is to make a solution in milk for it does not properly dissolve in water. Pure Aniracetam powder can be purchased for $17.99 for every 50 grams. Additionally you buy aniracetam in pill form as well which may make everything easier and as stated can be taken with any fatty food. You can see what other’s are stacking with aniracetam here.

Oxiracetam

oxiracetamA very potent analog of Piracetam which has swifter mode of action than both Piracetam and Aniracetam. It is in a class of its own as it is more expensive yet, has a smaller dose, yet more expensive than Piracetam.

Oxiracetam is very often used to improve motivation levels and to dismiss the symptoms of mental lethargy and fatigue, but it also comes out to be a cognitive enhancer apart from being a brain booster as many Racetams are popular for.

Effects:  Spatial memory is boosted with Oxiracetam use and learning abstract concepts is improved greatly. Oxiracetam increases choline acetylcholinetranferase levels which is responsible for the acetylcholine neurotransmitter.

ATP levels are increased with Oxiracetam, which provides added energy for harder cognitive tasks. Oxiracetam’s side effects are almost nonexistent, however some individuals report fatigue following longer periods of studying or work during the use of this Nootropic. It is best to consult a physician before starting Oxiracetam.

Dosage:  Oxiracetam dose is suggested at 750 – 1,600 mg a day. Most people should take their dose every 6 to 8 hours during studying or when performing any type of mentally tiring work.

How to Take: Oxiracetam is soluble in water. For ideal results, stack Alpha GPC and Oxiracetam together. You can buy oxiracetam in bulk for the lowest price online here.

Pramiracetam

pramiracetamPramiracetam has 30x more potency than Piracetam. It is found to be the strongest among all Racetams and has the longest half life as well. These qualities are attributable to the fact that it is soluble in fat and has a greater bio-availability.

Pramiracetam is stacked with other types of Nootropics and Racetams because it is known to greatly enhance the effectiveness of other compounds. More so it’s side effects anecdotally are said to be mild and equivalent to that of table salt.

Effects: Pramiracetam is particularly recognized for boosting mental energy levels and increasing alertness for up to 8 hours following its intake. It makes learning easier by enhancing memory and boosting neuroplasticity.

Dosage: Daily dosage for Pramiracetam is recommended at a much smaller amount for it is highly concentrated. In a 24 hour period between 100 – 1,200 mg of the compound should be taken. Most people will ingest one dose in the morning and a second one early in the afternoon to have the full effectiveness.

How to Take: Pramiracetam is found in white powder form and is soluble in fat. Like many fat soluble Racetams, you should make a solution with milk, not with water or with fish oil or krill oil. Click here to buy pramiracetam in powder or pill form.

To see other nootropic stacks, click here.

Piracetam Headache? How To Avoid this Side Effect

piracetam headachePiracetam is one of the most well researched and original cognitive enhancers. It is a supplement of the Racetam class. It is known to be a very modest neuroprotective and memory-improving agent which offers solid cognitive and neurological benefits, consolidated with essentially non-existing toxicity (less than that of table salt).

A very small percentage of those that use Racetams may experience unpleasant headaches. The headaches caused by Piracetam may last many hours after the initial intake or sometimes it can be very short-lived. Using Piracetam may also intensify migraines and headaches that are caused by some other stimuli.

So, what causes this adverse side effect to occur and what can you could do to avert it from happening to you? Before getting started, let’s see why people take Piracetam:

 

PROS of Piracetam*

  • Improves Reasoning and Cognition
  • Helps to Support Memory
  • Improves Perception and Alertness
  • Improves Mental Fatigue and Concentration

CONS*

  • Low Potency Compared to Other Racetams
  • May Cause Headaches in Some Users
  • Long Onset Period of Effects

 

Why Does Piracetam Cause Headaches?

piracetam headache cureAniracetam, Oxiracetam, Pramiracetam along with Piracetam stimulate the Acetylcholine receptors in the brain. Acetylcholine is possibly the most significant Neurotransmitter responsible for many brain related functions and is also responsible for functions in relation to learning, concentration and reasoning.

Acetylcholine is produced from the food we eat that contains choline, but in so many cases, humans do not get adequate amounts from just food alone. Evidence suggests that taking enough choline with Piracetam, may cause headaches to subside and or be prevented (reference). This is because Piracetam demands a high level of choline be present in our brain when supplemented, without it, your brain will give you a headache. You can think of it as similar to getting a headache from being dehydrated after running, with Piracetam your brain is “running” and choline is the source it needs to keep you going.

The liver makes very little amounts of choline, thus it may be beneficial to buy a choline supplement. Numerous foods contain choline, such as: egg yolks (250mg per egg roughly) and liver meat, regardless of its wide accessibility, scientists think many individuals don’t get sufficient levels of choline.

As per a popular anecdotal evidence, the use of Piracetam can often times overly tax an individual’s cholinergic system. If enough choline is not present in your food, then there is a chance that you might be choline deficient.  This can be evidenced from any of the racetam nootropics being consumed on our platform, most are “commonly paired or stacked with” one choline source or another, see aniracetam with AlphaGPC, phenylpiracetam with the same, and pramiracetam here.

How to Cure a Piracetam Headache?

If an individual is suffering from a consistent headache while using Piracetam, they should first try adding choline to their diet (food). Secondly consider stacking your choline powder of choice with Piracetam, see alpha gpc dosage amount, and choline bitartrate dosage amount here or you can also try Centrophenoxine.

You should start by adding a small dose initially (250mg if alpha gpc for example) and then can slowly increase the dosage until your headaches are gone. If you did not notice any effects from adding additional choline at up to ~750mg, continuing to add more may not help. Again see the Piracetam page to determine what the most ‘common’ ratios are to get an idea as to where to draw your limit and call it quits. E.g. If you consume 4.8g of Piracetam with 250mg of Alpha-GPC you may not notice the helpful effects of adding choline to your stack, however if you consume 1.8g to 500mg of AlphaGPC–you might just notice that you don’t have a headache.  Generally consuming choline is also a good habit in and of itself and can act as a cognitive enhancer as well, see choline+inositol stack.

Choline stacks and Headaches

Taking Piracetam alone can cause headaches among some people and with the addition of choline, the headaches may stop, however for a few people the opposite is true. Taking Choline with Piracetam can cause headaches while taking Piracetam alone does not. In this case you could be “choline dominant” and your best course of action could be to cease supplementing choline. Many people read and feel as if it is absolutely essential to take a choline source with the Racetams and that’s just not true. If you don’t need it and your body is telling you it doesn’t need it via headaches, stop or take half the dose and observe the results.

Many users when adding choline experience depression, brain fog, lethargy or fatigue. Some research demonstrates a relationship between depression and large amounts of choline in the brain. Having said that, the opposite research is also available, so as of now, you may need to test what works and doesn’t for you. You can search for many supplement stacks which contain choline here, add a choline source you have and Piracetam on the compound search bar in the textbox on the left menu of the page and see what other’s are doing.

What to Do If the Headaches Persist

Additionally, the problem can be caused be something totally unrelated to Choline as well, are you hydrated enough?, are you getting enough restful-sleep?, do you have any chronic conditions?, stress? could it be the result of a interaction with other drugs or supplements?

Tracking these variables is key, and if you do have a condition and or are on other drugs, you can see if other’s on TrackMyStack have had the same symptoms as you — which can help in determining the cause of the problem. You can spend time researching and learning/biohacking yourself but don’t forget to visit a professional who may be able to diagnose the issue much quicker.

Generally, Piracetam is not common drug to supplement in the Western part of the world, chances are your health care professional will not know anything about it and ask you to get off of it right of the bat — as it is the safest thing for them to recommend. Consider taking another ‘supplement’ (Piracetam is a synthetic drug) for cognitive enhancement (if that is your goal). Another option is to utilize a Nootropic with a alternate mechanism of action such as Adrafinil.