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Countdown to 40

Anti Aging 407 Updated: 2017-12-13 shikonaj
Using this stack to increase energy, improve the health of my hair, skin, and nails, and as a general anti-aging regimen since I'm counting down to 40.

215 Potential Effects from this Stack

Effect OnScaleContributors
Insulin Sensitivity5 Vanadium, Green Tea Catechins, Magnesium, Vitamin K, Vitamin D, Inositol, Vitamin E, Vitamin C, Red Clover Extract, Chromium, Zinc
Blood Flow4 Green Tea Catechins, Ginkgo biloba, Vitamin E, Vitamin C
Cognition4 Green Tea Catechins, Ginkgo biloba, Choline Bitartrate, Zinc
Sleep Quality3 Magnesium, Ginkgo biloba, Red Clover Extract
HDL-C2 Astaxanthin, Green Tea Catechins, Magnesium, Inositol, Vitamin E
Memory2 Ginkgo biloba, Vitamin E, Red Clover Extract, Chromium
Free Testosterone2 Astaxanthin, Green Tea Catechins, Magnesium, Vitamin D, Vitamin E, Red Clover Extract, Saw Palmetto, Chromium, Zinc
Lean Mass1 Vitamin D, Chromium
Skin dryness1 Vitamin A
Interleukin 41 Vitamin E
Fertility1 Inositol
Ocular Blood Flow1 Ginkgo biloba
Dysmenorrhea1 Vitamin E
Interferon Gamma1 Vitamin E
Immunity (aka Immune system)1 Vitamin E
Euphoric1 Ginkgo biloba, Vitamin E
Plasma Vitamin C1 Vitamin C
Libido1 Ginkgo biloba, Chromium
Calmness1 Ginkgo biloba
Skin pigmentation1 Vitamin A
Serum Magnesium1 Magnesium
Anaerobic Exercise1 Taurine, Chromium
Leptin1 Zinc
VO2 Max1 Green Tea Catechins, Vitamin C
Sperm Quality1 Astaxanthin, Vitamin C
CreatinineNeutral Chromium
Anti-Oxidant Enzyme ProfileNeutral Chromium
Red Blood Cell CountNeutral Vitamin E
DNA DamageNeutral Vitamin E
White Blood Cell CountNeutral Vitamin E
Cell Adhesion Factors (aka sCAM-1Neutral Vitamin E
PneumoniaNeutral Zinc
Symptoms of SchizophreniaNeutral Inositol
vLDL-CNeutral Chromium
Muscular EnduranceNeutral Chromium
Serum T3Neutral Vitamin E
Food IntakeNeutral Chromium
Serum T4Neutral Vitamin E
Aerobic ExerciseNeutral Vitamin C
Bleeding TimeNeutral Vitamin E
EstrogenNeutral Red Clover Extract
Exercise-Induced Immune SuppressionNeutral Vitamin C
Bone Mineral Density (aka BMD)Neutral Red Clover Extract
Protection from SmokingNeutral Vitamin C
Follicle-Stimulating Hormone (aka FSH)Neutral Red Clover Extract
Risk of StrokeNeutral Vitamin E
Colon cancer riskNeutral Vitamin E
Apolipoprotein ANeutral Red Clover Extract
Sex Hormone Binding Globulin (aka SHBG)Neutral Red Clover Extract
Breast Cancer RiskNeutral Vitamin E
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  • 2017-12-13 02:45:10: Methionine was added.
  • 2017-12-13 02:45:10: Dose quantity of Methionine was set to 100.
  • 2017-12-13 02:45:10: Dose unit of Methionine was set to 1.
  • 2017-12-13 02:45:10: Start date of Methionine was set to 2017-12-13.
  • 2017-12-13 02:45:10: Effectiveness of Methionine was set to Can't tell.
  • 2017-12-13 02:43:57: Dose quantity of Zinc was changed from 35.00 to 50.
  • 2017-12-13 02:43:36: Dose quantity of NOW Pantothenic Acid 250 Capsules was changed from 50050.00 to 60050.
  • 2017-12-13 02:42:52: Dose quantity of Biotin was changed from 10800.00 to 11100.
  • 2017-12-13 02:42:31: Dose quantity of Folic Acid was changed from 800.00 to 2200.
  • 2017-12-13 02:42:17: Dose quantity of Vitamin B6 was changed from 60.00 to 62.
  • 2017-12-13 02:41:58: Dose quantity of Niacinamide was changed from 80.00 to 100.
  • 2017-12-13 02:41:38: Dose quantity of Vitamin B1 was changed from 80.00 to 82.
  • 2017-12-13 02:40:24: Dose quantity of Vitamin E was changed from 45.00 to 75.
  • 2017-12-13 02:33:20: Dose quantity of Green Tea Catechins was changed from 10.00 to 170.
  • 2017-12-13 02:33:20: Dose status of Green Tea Catechins was cleared. Previous value was Under
  • 2017-12-13 02:32:42: Acai was added.
  • 2017-12-13 02:32:42: Dose quantity of Acai was set to 500.
  • 2017-12-13 02:32:42: Dose unit of Acai was set to 1.
  • 2017-12-13 02:32:42: Start date of Acai was set to 2017-12-13.
  • 2017-12-13 02:32:42: Effectiveness of Acai was set to Can't tell.
  • 2017-12-13 02:32:04: End date was set to 2017-12-13.
  • 2017-12-12 18:22:42: Vanadium was added.
  • 2017-12-12 18:22:42: Dose quantity of Vanadium was set to 10.
  • 2017-12-12 18:22:42: Dose unit of Vanadium was set to 3.
  • 2017-12-12 18:22:42: Dose status of Vanadium was set to Under.
  • 2017-12-12 18:22:42: Start date of Vanadium was set to 2017-12-12.
  • 2017-12-12 18:22:42: Effectiveness of Vanadium was set to Can't tell.
  • 2017-12-12 18:22:18: Astaxanthin was added.
  • 2017-12-12 18:22:18: Dose quantity of Astaxanthin was set to 50.
  • 2017-12-12 18:22:18: Dose unit of Astaxanthin was set to 3.
  • 2017-12-12 18:22:18: Dose status of Astaxanthin was set to Under.
  • 2017-12-12 18:22:18: Start date of Astaxanthin was set to 2017-12-12.
  • 2017-12-12 18:22:18: Effectiveness of Astaxanthin was set to Can't tell.
  • 2017-12-12 18:21:49: Dose quantity of Lycopene was changed from 950.00 to 1900.
  • 2017-12-12 18:21:13: Boron was added.
  • 2017-12-12 18:21:13: Dose quantity of Boron was set to 2.
  • 2017-12-12 18:21:13: Dose unit of Boron was set to 1.
  • 2017-12-12 18:21:13: Dose status of Boron was set to Under.
  • 2017-12-12 18:21:13: Start date of Boron was set to 2017-12-12.
  • 2017-12-12 18:21:13: Effectiveness of Boron was set to Can't tell.
  • 2017-12-12 18:20:32: Cranberry was added.
  • 2017-12-12 18:20:32: Dose quantity of Cranberry was set to 10.
  • 2017-12-12 18:20:32: Dose unit of Cranberry was set to 1.
  • 2017-12-12 18:20:32: Start date of Cranberry was set to 2017-12-12.
  • 2017-12-12 18:20:32: Effectiveness of Cranberry was set to Can't tell.
  • 2017-12-12 18:20:16: Green Tea Catechins was added.
  • 2017-12-12 18:20:16: Dose quantity of Green Tea Catechins was set to 10.
  • 2017-12-12 18:20:16: Dose unit of Green Tea Catechins was set to 1.
  • 2017-12-12 18:20:16: Dose status of Green Tea Catechins was set to Under.
  • 2017-12-12 18:20:16: Start date of Green Tea Catechins was set to 2017-12-12.
  • 2017-12-12 18:20:16: Effectiveness of Green Tea Catechins was set to Can't tell.
  • 2017-12-12 18:19:54: Dose quantity of Inositol was changed from 200.00 to 210.
  • 2017-12-12 18:19:54: Dose status of Inositol was cleared. Previous value was Recommended
  • 2017-12-12 18:19:41: Dose quantity of Choline Bitartrate was changed from 100.00 to 110.
  • 2017-12-12 18:19:41: Dose status of Choline Bitartrate was cleared. Previous value was Under
  • 2017-12-12 18:19:22: Alpha Lipoic Acid was added.
  • 2017-12-12 18:19:22: Dose quantity of Alpha Lipoic Acid was set to 25.
  • 2017-12-12 18:19:22: Dose unit of Alpha Lipoic Acid was set to 1.
  • 2017-12-12 18:19:22: Dose status of Alpha Lipoic Acid was set to Under.
  • 2017-12-12 18:19:22: Start date of Alpha Lipoic Acid was set to 2017-12-12.
  • 2017-12-12 18:19:22: Effectiveness of Alpha Lipoic Acid was set to Can't tell.
  • 2017-12-12 18:18:16: Lycopene was added.
  • 2017-12-12 18:18:16: Dose quantity of Lycopene was set to 950.
  • 2017-12-12 18:18:16: Dose unit of Lycopene was set to 3.
  • 2017-12-12 18:18:16: Start date of Lycopene was set to 2017-12-12.
  • 2017-12-12 18:18:16: Effectiveness of Lycopene was set to Can't tell.
  • 2017-12-12 18:17:22: Sodium Molybdate was added.
  • 2017-12-12 18:17:22: Dose quantity of Sodium Molybdate was set to 75.
  • 2017-12-12 18:17:22: Dose unit of Sodium Molybdate was set to 3.
  • 2017-12-12 18:17:22: Start date of Sodium Molybdate was set to 2017-12-12.
  • 2017-12-12 18:17:22: Effectiveness of Sodium Molybdate was set to Can't tell.
  • 2017-12-12 18:16:45: Dose quantity of Chromium was changed from 500.00 to 620.
  • 2017-12-12 18:16:45: Dose status of Chromium was cleared. Previous value was Under
  • 2017-12-12 18:16:05: Manganese was added.
  • 2017-12-12 18:16:05: Dose quantity of Manganese was set to 2.
  • 2017-12-12 18:16:05: Dose unit of Manganese was set to 1.
  • 2017-12-12 18:16:05: Start date of Manganese was set to 2017-12-12.
  • 2017-12-12 18:16:05: Effectiveness of Manganese was set to Can't tell.
  • 2017-12-12 18:15:35: Copper was added.
  • 2017-12-12 18:15:35: Dose quantity of Copper was set to 2.
  • 2017-12-12 18:15:35: Dose unit of Copper was set to 1.
  • 2017-12-12 18:15:35: Start date of Copper was set to 2017-12-12.
  • 2017-12-12 18:15:35: Effectiveness of Copper was set to Can't tell.
  • 2017-12-12 18:15:13: Selenium was added.
  • 2017-12-12 18:15:13: Dose quantity of Selenium was set to 200.
  • 2017-12-12 18:15:13: Dose unit of Selenium was set to 3.
  • 2017-12-12 18:15:13: Start date of Selenium was set to 2017-12-12.
  • 2017-12-12 18:15:13: Effectiveness of Selenium was set to Can't tell.
  • 2017-12-12 18:14:34: Dose quantity of Zinc was changed from 20.00 to 35.
  • 2017-12-12 18:14:11: Magnesium was added.
  • 2017-12-12 18:14:11: Dose quantity of Magnesium was set to 250.
  • 2017-12-12 18:14:11: Dose unit of Magnesium was set to 1.
  • 2017-12-12 18:14:11: Dose status of Magnesium was set to Recommended.
  • 2017-12-12 18:14:11: Start date of Magnesium was set to 2017-12-12.
  • 2017-12-12 18:14:11: Effectiveness of Magnesium was set to Can't tell.
  • 2017-12-12 18:13:48: Calcium was added.
  • 2017-12-12 18:13:48: Dose quantity of Calcium was set to 1000.
  • 2017-12-12 18:13:48: Dose unit of Calcium was set to 1.
  • 2017-12-12 18:13:48: Start date of Calcium was set to 2017-12-12.
  • 2017-12-12 18:13:48: Effectiveness of Calcium was set to Can't tell.

Dosage Compound Form Frequency Dates Notes
100 mg 1X1,1,1,1,1,1,12017-12-13
500 mg 1X1,1,1,1,1,1,12017-12-13
10 mcg 1X1,1,1,1,1,1,12017-12-12
50 mcg 1X1,1,1,1,1,1,12017-12-12
2 mg 1X1,1,1,1,1,1,12017-12-12
10 mg 1X1,1,1,1,1,1,12017-12-12
170 mg ,,,,,,2017-12-12
25 mg 1X1,1,1,1,1,1,12017-12-12
1900 mcg ,,,,,,2017-12-12
75 mcgSodium Molybdate 1X1,1,1,1,1,1,12017-12-12
2 mgManganese 1X1,1,1,1,1,1,12017-12-12
2 mg 1X1,1,1,1,1,1,12017-12-12
200 mcg 1X1,1,1,1,1,1,12017-12-12
250 mg 1X1,1,1,1,1,1,12017-12-12
1000 mg 1X1,1,1,1,1,1,12017-12-12
50 mcg 1X1,1,1,1,1,1,12017-12-12
80 mcg 1X1,1,1,1,1,1,12017-12-12
2000 iu 1X1,1,1,1,1,1,12017-12-12
50 mg 1X1,1,1,1,1,1,12017-12-12
100 mg 1X1,1,1,1,1,1,12017-12-12
100 mg 1X1,1,1,1,1,1,12017-12-12
110 mg ,,,,,,2017-12-12
210 mg ,,,,,,2017-12-12
60050 mcg ,,,,,,2017-12-12
100 mg ,,,,,,2017-12-12
2200 mcg ,,,,,,2017-12-12
62 mg ,,,,,,2017-12-12
82 mg ,,,,,,2017-12-12
15000 iu ,,,,,,2017-12-12
10 mg 1X1,1,1,1,1,1,12017-12-12
75 iu ,,,,,,2017-12-12
715 mg ,,,,,,2017-12-12
7 mg 1X1,1,1,1,1,1,12017-12-12
10 mg 1X1,1,1,1,1,1,12017-12-12
25 mg 1X1,1,1,1,1,1,12017-12-12
25 mgNOW Stinging Nettle Root Extract 250mg90 Vcaps 1X1,1,1,1,1,1,12017-12-12
25 mg 1X1,1,1,1,1,1,12017-12-12
25 mg 1X1,1,1,1,1,1,12017-12-12
30 mg 1X1,1,1,1,1,1,12017-12-12
50 mg 1X1,1,1,1,1,1,12017-12-12
150 mg ,,,,,,2017-12-12
50 mg 1X1,1,1,1,1,1,12017-12-12
75 mg 1X1,1,1,1,1,1,12017-12-12
100 mg 1X1,1,1,1,1,1,12017-12-12
240 mg ,,,,,,2017-12-12
800 mg ,,,,,,2017-12-12
620 mcgChromium ,,,,,,2017-12-12
50 mg ,,,,,,2017-12-12
11100 mcg ,,,,,,2017-12-12

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Countdown to 40



Potential Interactions
Boron may conserve the body’s use of calcium, magnesium, and vitamin D. In one study, the ability of boron to reduce urinary loss of calcium disappeared when subjects were also given magnesium. Therefore, boron may provide no special benefit in maintaining bone mass in the presence of adequate amounts of dietary magnesium.
Refrences
  • Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.
Intake of large amounts of vitamin C can deplete the body of copper—an essential nutrient. People should be sure to maintain adequate copper intake at higher intakes of vitamin C. Copper is found in many multivitamin-mineral supplements.
Refrences
  • Sandstead HH. Copper bioavailability and requirements. Am J Clin Nutr 1982;35:809-14 [review].
  • Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553-6.
Long-term supplementation with vitamin B6 alone might reduce blood folic acid levels. Therefore, people with elevated blood homocysteine levels should supplement with both folic acid and vitamin B6.
Refrences
  • Mansoor MA, Kristensen O, Hervig T, et al. Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate. Scand J Clin Lab Invest 1999;59:139-46.
There is some evidence that magnesium may enhance calcium absorption.
Refrences
  • Briscoe AM, Ragan C. Effect of magnesium on calcium metabolism in man. Am J Clin Nutr 1966;19:296-306.
Vitamin B1 (thiamine) and magnesium work together in several different biochemical processes in the body. In patients who are deficient in both thiamine and magnesium, symptoms of thiamine deficiency may not respond to thiamine supplementation unless magnesium deficiency is also corrected. In addition, administration of large doses of thiamine can worsen magnesium deficiency. Magnesium supplementation should therefore be considered by people who are supplementing with thiamine.
Refrences
  • Gaby AR. Magnesium. In Gaby AR, Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 27
Vitamin B6 increases the amount of magnesium that can enter cells. As a result, these two nutrients are often taken together.
Refrences
  • Abraham GE, Schwartz UD, Lubran MM. Effect of vitamin B-6 on plasma and red blood cell magnesium levels in premenopausal women. Ann Clin Lab Sci 1981;11:333-6.
Vitamin D’s most important role is maintaining blood levels of calcium. Therefore, many doctors recommend that those supplementing with calcium also supplement with 400–1,200 IU of vitamin D per day.
Refrences
  • Norman AW. Intestinal calcium absorption: a vitamin D-hormone-mediated adaptive response. Am J Clin Nutr 1990;51:290-300.
Vitamin E appears to increase intestinal absorption and tissue uptake of vitamin A. Because of this effect, some doctors have used the combination of vitamin E and vitamin A for various skin conditions that are usually treated with vitamin A alone. The addition of vitamin E improved outcomes, while allowing for lower (and safer) doses of vitamin A.
Refrences
  • Oaks L, Russell R, Jacob RA. Decreased serum vitamin A levels during vitamin E supplementation. Am J Clin Nutr 1978;31:716.
  • Ames SR. Factors affecting absorption, transport, and storage of vitamin A. The American journal of clinical nutrition. 1969 Jul;22(7):934-5
  • Gaby AR. Vitamin A. In Gaby AR. Nutritional Medicine. Concord, NH, www.doctorgaby.com, 2011; chapter 11.
Studies in animals and humans suggest that supplementation with large amounts of either vitamin C or vitamin E increases the requirement for the other nutrient.
Refrences
  • Chen LH. An increase in vitamin E requirement induced by high supplementation of vitamin C in rats. The American journal of clinical nutrition. 1981 Jun;34(6):1036-41
  • Brown KM,Morrice PC,Duthie GG. Erythrocyte vitamin E and plasma ascorbate concentrations in relation to erythrocyte peroxidation in smokers and nonsmokers: dose response to vitamin E supplementation. The American journal of clinical nutrition. 1997 Feb;65(2):496-502
Supplementation with zinc, iron, or the combination has been found to improve vitamin A status among children at high risk for deficiency of the three nutrients. This interaction has only been shown in a developing country with higher incidence of multiple deficiencies.
Refrences
  • Muñoz EC, Rosado JL, Lopez P, et al. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am J Clin Nutr 2000;71:789-94.
Zinc competes for absorption with calcium. A multimineral supplement will help prevent mineral imbalances.
Refrences
  • Argiratos V, Samman S. The effect of calcium carbonate and calcium citrate on the absorption of zinc in healthy female subjects. Eur J Clin Nutr 1994;48:198-204.

Supplementing with folic acid in amounts as little as 300 to 800 mcg per day may increase vitamin B12 requirements. Therefore, it would be prudent for people taking folic acid to supplement with vitamin B12.

Supplementation with vitamin B12, even in relatively small amounts, can increase folic acid requirements, For that reason, people taking vitamin B12 supplements should also consider taking folic acid.

In addition, supplementing with folic acid can mask the laboratory diagnosis of vitamin B12 deficiency. Failure to identify and treat vitamin B12 deficiency in a timely manner can lead to permanent neurological damage. The relatively small amount of vitamin B12 present in most supplements is not sufficient to prevent or correct vitamin B12 deficiency in people who have pernicious anemia (a condition caused by vitamin B12 malabsorption). For that reason, people should tell their doctor if they are taking folic acid supplements, so that the doctor will order alternative laboratory tests if vitamin B12 deficiency is suspected.


Refrences
  • Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5.
  • Steiner I,Melamed E. Folic acid and the nervous system. Neurology. 1983 Dec;33(12):1634
The Canadian Health Protection Branch requires supplement manufacturers to document that their products do not contain the enzyme thiaminase, found in crude horsetail, which destroys the B vitamin thiamine. Since alcohol, temperature, and alkalinity neutralize this potentially harmful enzyme, tinctures, fluid extracts, or preparations of the herb subjected to 100°C temperatures during manufacturing are preferred for medicinal use.
Refrences
  • Fabre B, Geay B, Beaufils P. Thiaminase activity in Equisetum arvense and its extracts. Plant Med Phytother 1993;26:190-7.
Vitamin C appears to convert sodium selenite (a form of selenium used for supplementation) to elemental selenium, making it unavailable for absorption. This interaction occurred when 1 g of vitamin C was taken with sodium selenite on an empty stomach, but not when these nutrients were taken together with a meal. Vitamin C does not appear to interact with selenomethionine, another commonly used form of supplemental selenium.
Refrences
  • Robinson MF,Thomson CD,Huemmer PK. Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite. The New Zealand medical journal. 1985 Aug;98(784):627-9
  • Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. Journal of the National Cancer Institute. 1986 Jul;77(1):299-303
In a study of healthy men, supplementation with a large amount of zinc (142 mg per day) decreased magnesium absorption. Magnesium supplementation should therefore be considered for people taking large amounts of zinc, and possibly for those taking lower amounts.
Refrences
  • Spencer H, Norris C, Williams D. Inhibitory effects of zinc on magnesium balance and magnesium absorption in man. J Am Coll Nutr 1994;13:479-84.
Zinc competes for absorption with copper  and inhibits copper absorption. Copper deficiency can result in anemia, lower levels of HDL (“good”) cholesterol, neurological disorders, and cardiac arrhythmias. Copper intake should be increased if zinc supplementation continues for more than a few days (except for people with Wilson’s disease). Some sources recommend a 10:1 ratio of zinc to copper. Evidence suggests that no more that 2 mg of copper per day is needed to prevent zinc-induced copper deficiency. Many zinc supplements include copper in the formulation to prevent zinc-induced copper deficiency. Zinc-induced copper deficiency has been reported to cause reversible anemia and suppression of bone marrow. In addition, there are case reports of neurologic abnormalities due to copper deficiency occurring in people who had been using large amounts of certain widely available denture creams that contained high concentrations of zinc.
Refrences
  • Dawson EB, Albers J, McGanity WJ. Serum zinc changes due to iron supplementation in teen-age pregnancy. Am J Clin Nutr 1990;50:848-52.
  • Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.
  • Reiser S, Powell A, Yang CY, Canary JJ. Effect of copper intake on blood cholesterol and its lipoprotein distribution in men. Nutr Rep Int 1987;36:641-9.
  • Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].
  • Fischer PWF, Giroux A, Labbe MR. Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr 1984;40:743-6.
  • Nations SP, Boyer PJ, Love LA, et al. Denture cream. An unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008;71:639-43.

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