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Aniracetam vs Piracetam

Aniracetam vs Piracetam Comparison, Similarities & Differences


Read full Aniracetam Review


Read our Aniracetam Review

Aniracetam is a nootropic supplement under the racetam class that is regarded as being significantly more powerful than Piracetam. In addition to the cognitive enhancement it provides, it also acts as an anxiolytic and improves mood, memory and focus. This is likely achieved through its effects on the D2 dopamine receptors, acetylcholine receptors, and 5-HT2A receptors. However, it is still under investigational usage for treating various neurodegenerative disorders. It also has an effect on the AMPA receptor and is a drug that is thought to offer benefits for individuals with neurodegenerative disorders. Throughout European countries, it can be obtained as a prescription drug, but has never received any approval by the FDA for usage in the U.S. Aniracetam is fat soluble.

Piracetam is the first compound developed under the racetam class and was synthetically created by Belgium lab UCB Pharma. Of the racetam class, this is perhaps the most discussed and utilized nootropic. Its mechanism of action is poorly understood, but many speculate that it improves cognition without stimulating or sedating properties. In other words, it doesn't seem to affect a person's arousal. It is a modulator of the AMPA receptor and may work on various ion channels within the brain to excite neurons. Additionally, it improves acetylcholine functioning and may influence NMDA glutamate receptors. There is some evidence that it increases the amount of blood flow and oxygen to the brain. It is not approved in the United States for any condition, but is approved in the United Kingdom. In recent years it has gained popularity among students as a way to increase academic performance.


1-p-anisoyl-2-pyrrilidinone, Ro 13-5057, CAS 72432-10-1, 14-methoxybenzoyl-2-pyrrolidinone, Draganon, Sarpul, Ampamet, Memodrin, Referan

Pyracetam, Pyrrolidone acetamide, 2-Oxo-1-pyrrolidine, Memotopril, Fezam with cinnarizine, UCB6215


1,500 mg/day broken into doses of two or as needed.
Daily Dosage # Stacks
750.00 mg 29
500.00 mg 14
1500.00 mg 13
1000.00 mg 4
250.00 mg 3
650.00 mg 3
325.00 mg 2
1.00 g 2
700.00 mg 2
400.00 mg 2

4.8 g daily/2x dose. 40-100mg/kg.
Daily Dosage # Stacks
800.00 mg 11
4.80 g 7
2.00 g 7
1600.00 mg 7
2.40 g 6
3.00 g 5
1200.00 mg 4
250.00 mg 4
2400.00 mg 3
2000.00 mg 2

Side Effects

The most notable side effect of Aniracetam is headaches.

Side Effects # Stacks
Fatigue 2

Like all the other racetams, Piracetam may be strongly associated with headaches. However, it can be eliminated easily with the addition of Choline.


Total Users

There are over 93 users currently taking this supplement.

There are over 101 users currently taking this supplement.


4.00/5 based on 9 user votes

3.00/5 based on 3 user votes

Evidence-Based Effects

  • Anxiety - Decreased
  • Cognition - Increased
  • Depression - Decreased
  • Memory - Increased

  • Cognitive Decline - Decreased
  • Memory - Increased

Similar Comparisons

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No data available

Medical Conditions

Medical Symptoms

Medical Symptoms # Stacks
Fatigue 2
Sweating excessive 1
Brain fog 1


Purpose # Stacks Effectiveness
Fatigue 2
Can't tell

Purpose # Stacks Effectiveness
Lack of motivation 1
Can't tell
Fatigue 1
Can't tell

Commonly Paired With

Commonly Paired With # Stacks
Alpha GPC 62
Noopept 51
L-Theanine 51
Fish Oil 32
Caffeine 32
AcetylCarnitine 26

Commonly Paired With # Stacks
Fish Oil 47
Noopept 43
L-Theanine 43
Alpha GPC 42
Citicoline (CDP-Choline) 24
Caffeine 23

Price & Brand

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