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Vitex agnus castus vs Lions Mane

Vitex agnus castus vs Lions Mane Comparison, Similarities & Differences

Vitex Agnus Castus

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Lions Mane

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Vitex agnus castus refers to the fruit of the chaste tree and has been used to make medicine. It is sometimes called "the women's herb" since it has been used to treat menstrual cycle irregularities, premenstrual syndrome, symptoms of menopause, and premenstrual dysphoric disorder, which is a more severe form of PMS. Moreover, it has also been used to treat female infertility and "lumpy" breasts, in preventing miscarriage, in controlling bleeding, and also in increasing breast milk. These health benefits particularly in women may be attributed to Vitex agnus castus affecting many hormones that regulate women's reproductive cycles. On the other hand, Vitex agnus castus is also used for headaches, migraine, eye pain, inflammation, colds, upset stomach, dementia, acne, nervousness, and joint conditions.

Lion's Mane is a mushroom (Yamabushitake) that has been used in Chinese traditional medicine for hundreds of years now. It is believed that various properties of the mushroom act a antioxidant. Moreover, it is now recognized as one of the best natural nootropics available as it increases Nerve Growth Factor levels in the brain, increasing neuronal growth rates and improving synaptic plasticity. Some researchers have suggested that this mushroom is able to improve mental functioning in those with impaired cognition. However, the long-term effects of this mushroom aren't well documented.


Chaste Tree, VAC, Chasteberry

Hericium erinaceus, Yamabushitake, Lion's Mane Mushroom, Monkey's Head, Igelstachelbart, Pom Pom Blanc, Hedgehog Mushroom, Satyr’s Beard


The appropriate dosage of Vitex agnus castus greatly depends on several factors such as the individual's age, health, and condition. It would be best to consult your healthcare provider first for the proper dosage of Vitex agnus castus.

No dosage data available


No dosage data available

Side Effects

Vitex agnus castus is likely safe to use however, it may produce some side effects such as headaches, nausea, itching, rashes, acne, trouble sleeping, and weight gain.

Possibly itchy skin.


Total Users

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There are no users taking this supplement.



4.17/5 based on 5 user votes

Evidence-Based Effects

  • Anxiety - Decreased
  • Breast Tenderness - Decreased
  • Depression - Decreased
  • Sleep Quality - Decreased
  • Symptoms of PMS - Decreased

  • Anxiety - Decreased
  • Cognitive Decline - Decreased
  • Depression - Decreased


No data available

Medical Conditions

No data available

Medical Symptoms

No data available


No data available

Commonly Paired With

No data available

Price & Brand

Editors RecommendationCertified Pick:
Vitex agnus castus

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