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Saffron vs Vitex agnus castus

Saffron vs Vitex agnus castus Comparison, Similarities & Differences


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Vitex Agnus Castus

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Saffron is a spice that is derived from the flower of Saffron crocus or Crocus sativus and is considered to be one of the world's most expensive spices. It has been used for the treatment of various conditions such as asthma, cough, pertussis, and is used as an expectorant. Moreover, Saffron is also used for menstrual cramps, premenstrual syndrome, insomnia, cancer, atherosclerosis, flatulence, depression, Alzheimer's disease, hemoptysis, pain, heartburn, dry skin, fright, and shock. On the other hand, it has also shown to have aphrodisiac properties as well as having the ability to induce sweating.

Vitex agnus castus refers to the fruit of the chaste tree and has been used to make medicine. It is sometimes called "the women's herb" since it has been used to treat menstrual cycle irregularities, premenstrual syndrome, symptoms of menopause, and premenstrual dysphoric disorder, which is a more severe form of PMS. Moreover, it has also been used to treat female infertility and "lumpy" breasts, in preventing miscarriage, in controlling bleeding, and also in increasing breast milk. These health benefits particularly in women may be attributed to Vitex agnus castus affecting many hormones that regulate women's reproductive cycles. On the other hand, Vitex agnus castus is also used for headaches, migraine, eye pain, inflammation, colds, upset stomach, dementia, acne, nervousness, and joint conditions.


Crocus sativus

Chaste Tree, VAC, Chasteberry


According to studies, the recommended dosage for Saffron includes the following: For depression, 30mg/day single dose or a dose of 15mg taken twice daily. For premenstrual syndrome, a dose of 15mg taken twice daily may be used.

No dosage data available

The appropriate dosage of Vitex agnus castus greatly depends on several factors such as the individual's age, health, and condition. It would be best to consult your healthcare provider first for the proper dosage of Vitex agnus castus.

No dosage data available

Side Effects

Saffron has been associated with some side effects including headaches, nausea, anxiety, dizziness, dry mouth, drowsiness, changes in appetite, and allergic reactions may also occur.

Vitex agnus castus is likely safe to use however, it may produce some side effects such as headaches, nausea, itching, rashes, acne, trouble sleeping, and weight gain.


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Evidence-Based Effects

  • Anxiety - Decreased
  • Blood Pressure - Decreased
  • Cortisol - Decreased
  • Depression - Decreased
  • Symptoms of Alzheimers - Decreased

  • Anxiety - Decreased
  • Breast Tenderness - Decreased
  • Depression - Decreased
  • Sleep Quality - Decreased
  • Symptoms of PMS - Decreased


No data available

Medical Conditions

No data available

Medical Symptoms

No data available


No data available

Commonly Paired With

No data available

Price & Brand

Editors RecommendationCertified Pick:
Vitex agnus castus

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