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SAMe vs Agmatine

SAMe vs Agmatine Comparison, Similarities & Differences

SAMe

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Agmatine

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SAMe, also known as S-Adenosyl Methionine, is a supplement made from Adenosine Triphosphate and Methionine and is used as a treatment for mild depression, boosting mood and nergy levels. Nootropic benefit is thought to be derived from the fact that SAMe may reduce brain inflammation, which preserves optimal brain functioning. This substance is believed to help the brain to produce and break down Serotonin, Melatonin, and Dopamine. Moreover, some studies show that it has the ability to inhibit the growth and development of cancer tumor cells and may be helpful in improving mood for patients with Parkinson's disease.



This is a natural compound that was discovered in the early 1900s when scientists decarboxylated the amino acid arginine meaning to say, the carboxylic acid group was removed from Arginine. From a nootropic perspective, agmatine is known to aid in neurotransmission within the brain. It accomplishes this by influencing ion channels, membrane transportation, modulation of nitric oxide, and metabolic processing of polyamine. It is able to cross the blood-brain barrier and functions to improve mood and reduce anxiety. It is also known to influence the Alpha-2 receptor in the adrenergic system and can inhibit some NMDA receptors.

Tradenames

S-Adenosyl-L-Methionine





Agmatine sulfate, Clonidine-displacing substance, 4-aminobutylguanidine, Decarboxylated arginine

Dose



No dosage data available





1300-2670mg

No dosage data available

Side Effects

Some side effects associated with SAMe usage include headaches, nausea, diarrhea, anxiety, restlessness, insomnia, and heart palpitations.






Classification









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There are no users taking this supplement.


Rated


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Evidence-Based Effects









  • Pain - Decreased

Duration




No data available

Medical Conditions




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Medical Symptoms




No data available

Purpose




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Commonly Paired With




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Price & Brand





Editors RecommendationCertified Pick:
Agmatine

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Cost: $16.95
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