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Piracetam vs Vinpocetine

Piracetam vs Vinpocetine Comparison, Similarities & Differences

Piracetam

Read full Piracetam Review

Vinpocetine

Read our Piracetam Review

Piracetam is the first compound developed under the racetam class and was synthetically created by Belgium lab UCB Pharma. Of the racetam class, this is perhaps the most discussed and utilized nootropic. Its mechanism of action is poorly understood, but many speculate that it improves cognition without stimulating or sedating properties. In other words, it doesn't seem to affect a person's arousal. It is a modulator of the AMPA receptor and may work on various ion channels within the brain to excite neurons. Additionally, it improves acetylcholine functioning and may influence NMDA glutamate receptors. There is some evidence that it increases the amount of blood flow and oxygen to the brain. It is not approved in the United States for any condition, but is approved in the United Kingdom. In recent years it has gained popularity among students as a way to increase academic performance.



Vinpocetine is a semisynthetic drug that contains Vinca minor extracts from the periwinkle plant. It is a vasodilator, meaning it increases the amount of blood flow within the cerebral cotrex thus, improving memory and cognition. Some suggest that it may have neuroprotective properties and improve memory impairment associated with aging. It also has anti-inflammatory effects, which may make it useful in combating symptoms of neurodegenerative disorders. Several clinical trials have been conducted with this drug on those with neurodegenerative disorders, but results are controversial. It works via the inhibition of voltage-sensitive sodium channels, thus preventing damage to neurons. It is considered tolerable in humans, but the tolerability over the long-term is unknown.

Tradenames

Pyracetam, Pyrrolidone acetamide, 2-Oxo-1-pyrrolidine, Memotopril, Fezam with cinnarizine, UCB6215





Vincamine, Vinca Minor, Periwinkle Extract, Cavinton Brand Name, ethyl apovincaminate

Dose

4.8 g daily/2x dose. 40-100mg/kg.

No dosage data available





15-60mg

No dosage data available

Side Effects

Like all the other racetams, Piracetam may be strongly associated with headaches. However, it can be eliminated easily with the addition of Choline.





Vinpocetine may cause gastrointestinal problems, nausea, headache, dizziness, nervousness, and sleep disturbances.

Classification









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Rated


3.00/5 based on 3 user votes








4.00/5 based on 3 user votes

Evidence-Based Effects


  • Cognitive Decline - Decreased
  • Memory - Increased







  • Memory - Increased

Duration




No data available

Medical Conditions




No data available

Medical Symptoms




No data available

Purpose




No data available

Commonly Paired With




No data available

Price & Brand


Editors RecommendationCertified Pick:
Piracetam

Buy Piracetam Supplement
Cost: Too low to display Buy Piracetam



Editors RecommendationCertified Pick:
Vinpocetine

Buy Vinpocetine Supplement
Cost: $17.95
Buy Vinpocetine

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