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Creatine vs Leucic Acid

Creatine vs Leucic Acid Comparison, Similarities & Differences


Read full Creatine Review

Leucic Acid

Read our Creatine Review

Creatine is a nitrogeous organic acid present in all vertebrates, including humans and is more commonly used by bodybuilders due to the energizing effects it provides to the working muscles. It has gained its popularity since it provides better neuronal health and improved mental energy. Moreover, taking creatine has been shown to boost cognitive function among those who eat primarily a vegetarian diet. Double blind, placebo-controlled studies have verified this finding, but it is unknown to what degree meat eaters would experience benefit because meat provides omnivores with a significant supply of dietary creatine.

Leucic Acid is a metabolite of leucine, a branched-chain amino acid. At the present, it is commonly sold as a purported muscle building supplement while having fungicidal properties. Leucic Acid has been used by athletes and body builders because it has shown to increase protein synthesis and muscle mass in clinical studies with rat subjects who ere recovering from a period of induced atrophy. However, further studies and clinical trials should still be conducted with Leucic Acid for its more potential benefits to the human health.


a-methylguanidinoacetic acid, creatine monohydrate, creatine 2-oxopropanoate

Alpha-Hydroxy-isocaproic acid, DL-alpha-Hydroxy-isocaproic acid, HICA



No dosage data available

No dosage data available

Side Effects

It is considered to be relatively safe to use although not yet confirmed, some potential side effects may include kidney damage, muscle cramps, dehydration, heart problems, and gastrointestinal problems.

There is liited information about the side effects that Leucic Acid may bring.


Total Users

There are no users taking this supplement.

There are no users taking this supplement.


5.00/5 based on 3 user votes


Evidence-Based Effects

  • Anaerobic Exercise - Increased
  • Blood Glucose - Decreased
  • Bone Mineral Density (aka BMD) - Increased
  • Depression - Decreased
  • Fatigue - Decreased
  • Fatigue Resistance - Increased
  • Free Testosterone - Increased
  • Growth Hormone - Increased
  • Homocysteine - Decreased
  • Hydration - Increased
  • Lean Mass - Increased
  • Lipid Peroxidation - Decreased
  • Muscle Damage - Decreased
  • Muscular Endurance - Increased
  • Power Output - Increased
  • Euphoric - Increased
  • VO2 Max - Increased
  • Treatment of Myotonic Dystrophy - Increased

  • Lean Mass - Increased


No data available

Medical Conditions

No data available

Medical Symptoms

No data available


No data available

Commonly Paired With

No data available

Price & Brand

Editors RecommendationCertified Pick:

Buy Creatine Supplement
Cost: $17.46 Buy Creatine

Editors RecommendationCertified Pick:
Leucic Acid

Buy Leucic Acid Supplement
Cost: $22.99
Buy Leucic Acid

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