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Alpha GPC vs DMAE

Alpha GPC vs DMAE Comparison, Similarities & Differences

Alpha GPC

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Also known as L-Alpha glycerylphosphorylcholine or choline alfoscerate, is a natural compound of choline that is present within the brain. It is regarded as having a potential to treat age-related memory loss, such as Alzheimer's disease, dementia, and stroke, and has neuroprotective properties that may be used as an anxiolytic. This nootropic is able to deliver choline to the brain bypassing the blood-brain barrier easily. It is available as a non-prescription supplement in most countries and is thought to be generally safe for consumption.

DMAE, also known as dimethylaminoethanol or Deanol is an alcohol produced inside the human brain. It could also be obtained from food sources like fish. It's believed that DMAE is needed for building choline thus enhancing cognitive function through improved communication between neurons. In many studies, DMAE has improved alertness, vigilance and also improved mood in people with emotional issues such as ADHD, Alzheimer's disease, Autism, and Tardive Dyskinesia.


Alpha-glycerylphosphorylcholine, L-alpha-glycerophosphocholin, glycerophosphocholine, L-alpha-glyceryl-phosphorylcholine, Choline Alphoscerate

Dimethylaminoethanol, dimethylethanolamine, Deanol cream


250mg to 1,200 mg

No dosage data available

300mg to 2000mg daily. Taken 1-3 times.

No dosage data available

Side Effects

This supplement appears to be safe for healthy adults.

Generally safe for use when it is used orally or topically.


Total Users

There are no users taking this supplement.

There are no users taking this supplement.


4.39/5 based on 8 user votes

4.00/5 based on 2 user votes

Evidence-Based Effects

  • Cognition - Increased
  • Cognitive Decline - Decreased
  • Growth Hormone - Increased
  • Power Output - Increased
  • Symptoms of Alzheimers - Decreased


No data available

Medical Conditions

No data available

Medical Symptoms

No data available


No data available

Commonly Paired With

No data available

Price & Brand

Editors RecommendationCertified Pick:
Alpha GPC

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