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Alpha GPC vs Citicoline (CDP-Choline) Comparison, Similarities & Differences between Alpha GPC vs. Citicoline (CDP-Choline)

Alpha GPC

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Citicoline (CDP-Choline)

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Also known as L-Alpha glycerylphosphorylcholine or choline alfoscerate, is a natural compound of choline that is present within the brain. It is regarded as having a potential to treat age-related memory loss, such as Alzheimer's disease, dementia, and stroke, and has neuroprotective properties that may be used as an anxiolytic. This nootropic is able to deliver choline to the brain bypassing the blood-brain barrier easily. It is available as a non-prescription supplement in most countries and is thought to be generally safe for consumption.

Citicoline, also known as CDP Choline, Cytidine diphosphate-choline, is a popular nootropic known to improve cognitive function and brain health. It mainly increases the levels of Acetylcholine in the brain thus, improving memory and communication between neurons. Also, it is thought to increase the density of dopamine receptors in the brain. Researches also suggest that Citicoline has been used to treat stroke, head trauma, and a number of cognitive disorders like dementia and age related cognitive decline. Some have gone as far as to suggest it may be helpful in treating symptoms of ADHD. It is available as a supplement in most established countries and is believed to have significant neuroprotective properties.


Alpha-glycerylphosphorylcholine, L-alpha-glycerophosphocholin, glycerophosphocholine, L-alpha-glyceryl-phosphorylcholine, Choline Alphoscerate


Citicholine, Cytidine Diphosphocholine


250mg to 1,200 mg
Daily Dosage # Stacks
300.00 mg 70
400.00 mg 36
600.00 mg 13
250.00 mg 12
500.00 mg 7
150.00 mg 6
100.00 mg 6
40.00 mg 4
200.00 mg 4
1000.00 mg 3


2,000 mg
Daily Dosage # Stacks
250.00 mg 9
500.00 mg 6
400.00 mg 5
300.00 mg 5
1000.00 mg 4
200.00 mg 4
100.00 mg 2
750.00 mg 1
60.00 mg 1
4800.00 mg 1

Side Effects

This supplement appears to be safe for healthy adults.


A few reported side effects of Citicoline use are generally mild and includes headaches, diarrhea, nausea, insomnia, and other gastrointestinal problems.



Total Users

There are over 160 users currently taking this supplement.


There are over 41 users currently taking this supplement.


4.39/5 based on 8 user votes


4.33/5 based on 3 user votes

Evidence-Based Effects

  • Cognition - Improved
  • Cognitive Decline - Decreases
  • Growth Hormone - Improved
  • Power Output - Improved
  • Symptoms of Alzheimers - Decreases


  • Attention - Improved
  • Blood Pressure - Decreases
  • Cognition - Improved
  • Memory - Improved
  • Cocaine Addiction - Decreases

Similar Comparisons


Compare Citicoline (CDP-Choline) vs Choline Citrate
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Compare Citicoline (CDP-Choline) vs Phosphatidylcholine



No data available

Medical Conditions


Medical Symptoms

Medical Symptoms # Stacks
Fatigue 1

Medical Symptoms # Stacks
Brain fog 1



No data available

Commonly Paired With

Commonly Paired With # Stacks
Noopept 111
L-Theanine 109
Fish Oil 78
AcetyLcarnitine 55
Aniracetam 49
Magnesium 46

Commonly Paired With # Stacks
Noopept 24
Fish Oil 18
L-Theanine 18
Piracetam 15
AcetyLcarnitine 15
Uridine 13

Price & Brand

Editors RecommendationCertified Pick:
Alpha GPC
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