The Real Limitless Drug
The film Limitless, which stars Bradley Cooper, Arbie Cornish, and Robert Deniro, has made a huge impact on society. This is mainly because it revolves around mental capabilities and how we could unlock our full potential just by taking a single pill- the NZT 48 drug.
What is NZT?
In the film, NZT-48 is such a powerful drug that it makes Bradley Cooper, known as Eddie Mora in the movie, unlock his full potential. He is superhuman when he takes the pill; not only is he able to use 20% of his brain’s capacity, but he is able to go much beyond that.
In reality, we use 100% of our brain, not all the time, but we use different parts of our brain for different things, the 20% of our brain usage is a urban myth. Anyways Bradley becomes the smartest living creature, doesn’t run out of energy, is able to learn languages and make a lot of money in the stock market. Would this be something you would take?
Does NZT48 really exist? The truth is, NZT-48 is just a creation of fiction and it was created to sell the movie. So the question is, why do we have the need to talk about this topic? Does it only give us a dream, or a false hope of using our brain’s potential 100% of the time? Even though NZT-48 is not real, there’s supplements and drugs referred to as Nootropics and they are starting to appear promising.
What are Nootropics and are they close to NZT?
By definition, nootropics are drugs that can protect your brain, enhance memory and/or other cognitive functions. They serve to promote enhancement in memory and facilitation of learning (1). Among the most famous nootropics today is the Racetam family and the first nootropic drug to be used widely was Piracetam, a synthetic derivative of GABA, also known as aminobutyric acid. You don’t need to remember this, although if you were on it, it wouldn’t be hard..would it?
Although its mechanism of action is still not fully understood, studies show that Piracetam positively affects the release of neurotransmitters in our brain and their receptor-binding capabilities. This improves cell functioning and leads to cognitive enhancements such as more efficient and easier memory formation, and memory recall. Also, Piracetam is involved in the activation of Acetylcholine, an important neurotransmitter in the brain related to memory processes and development (2). It is fairly easy to buy online as well and is considered safer than table salt (when you look at the LD50).
At present, various nootropics have already been discovered; these are much more potent than the parent compound Pireacetam. These smart drugs have a wider array of cognitive benefits and improve other areas like mood, behaviour, energy, and others. One such smart drug is Noopept — it is believed to be 1000x more potent than its derivative Piracetam. Other familiar nootropics also include Phenylpiracetam– also a derivative of Piracetam and is believed to be 30-60x more potent than its parent compound Piracetam.
One notable feature is that it has a phenyl ring added to the original structure, giving it a higher affinity for Norepinephrine and Dopamine, and making it easier to cross the Blood-Brain Barrier or BBB. Moreover, it enhances physical performance and gives stimulating and energizing effects through an increase in Noradrenaline levels.
Although athletes find this very useful, it is banned in the Olympics due to its psychostimulatory and cold resistance properties. Phenylpiracetam also has the ability to motivate and reduce the effects of anxiety and stress. Finally, other various smart drugs known in the market today include Pramiracetam, Aniracetam, Alpha GPC, Citicoline, Phenibut, and many more.
Through gradual research and experiment, a lot of smart drugs today show a large resemblance to NZT-48. The above are marketed as supplements but the FDA would not classify them as supplements. There are some drugs that are approved by the FDA (in America, it is the regulatory agency, and we will talk about that below).
Is Modafinil the original limitless pill?
Is modafinil really the original nzt48 pill? Consider Adrafinil, as the legal limitless pill and is available for sale online. Is it also a fictional drug like the NZT-48? Well here is the good news, Modafinil in contrast with NZT48, is a real-life drug. Yes you heard it right, Modafinil is not just available on our television screens, but we can actually buy it. But how is Modafinil related to the limitless pill NZT-48? Modafinil was actually the inspiration for NZT-48. It is used as a wakefulness-promoting agent primarily used to treat Narcolepsy (a condition causing excessive daytime sleepiness), shift work sleep disorder, and other sleep disorders.
Its wakefulness-promoting properties and increase in energy levels may be attributed its role as an adrenergic receptor agonist. It activates orexins/hypocretins (these are brain peptides) thus, increasing dopamine, norepinephrine and histamine levels. Moreover, Modafinil serves to improve memory and brain function through enhanced neuronal stimulation; more specifically, positive stimulation of Glutamate receptors and inhibition of Glutamate breakdown.
Because of Modafinil’s mechanism of action, it is the drug that is the closest thing to limitless pill NZT 48. Soon we will also review Donepezil which many now consider a limitless like pill as well. Modafinil is obviously a prescription drug and there can be many side effects, however with a good diet and proper nootropic supplementation you can ‘generally’ always feel noticeably smarter than your baseline, it is like body building, you can take supplements to go from your baseline to your absolute genetic potential but then as bodybuilders take steroids, drugs like modafinil can be used to push the brain to it’s capacity and thus we don’t recommend anyone try it right off the bat, especially not without consulting a physician.
Although NZT-48 may just be a fictional drug–the idea is real, there are a lot of promising smart drugs in the market that offer similar benefits. One supplement may provide benefits in one facet, but when stacked with others may be the complete regimen you need to feel more intelligent. We urge you to browse different stacks and see the results people are getting. A popular example of stacking is the combination of Racetams with Cholinergics.
For instance, the actions of racetams are attenuated due to an increased level of neurotransmitters that are essential for brain functioning. Be sure to track your results over time to see how the changes are affecting you. If you would like to skip nootropics and go straight to a nzt like smart drug consider buying adrafinil (modafinil precursor) here.